Article
Biotechnology & Applied Microbiology
Guanting Liu, Takumi Ito, Yusuke Kijima, Kazutoshi Yoshitake, Shuichi Asakawa, Shugo Watabe, Shigeharu Kinoshita
Summary: This study applied spatial transcriptomics to examine the muscle structure and growth characteristics of zebrafish myotomal muscle. The results revealed distinct regions with different gene expression patterns in adult muscles, which were similar to those found in larval muscles.
Article
Biochemistry & Molecular Biology
Chiara Maria Motta, Emanuela Califano, Rosaria Scudiero, Bice Avallone, Chiara Fogliano, Salvatore De Bonis, Anja Raggio, Palma Simoniello
Summary: The present study investigated the effects of cadmium on the gut mucosa and goblet cells of Danio rerio. The results showed that cadmium altered the distribution of glycans and affected the expression and localization of metallothionein. This interference can impair the mucosal efficiency and pose a health risk to organisms in direct contact with contamination and the trophic chain.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Fisheries
Fan Lin, Jiali Lin, Xin Liu, Yuying Yuan, Guoquan Liu, Xiaokang Ye
Summary: Collagen plays a crucial role in maintaining muscle growth and texture in fish, with temperature affecting collagen metabolism and muscle growth significantly. Lower temperatures enhance collagen deposition but decrease growth performance, while the transcription of collagen genes and protein processing in the endoplasmic reticulum pathway are affected by temperature.
AQUACULTURE REPORTS
(2022)
Article
Multidisciplinary Sciences
A. Printzi, D. Mazurais, P. E. Witten, L. Madec, A-A Gonzalez, X. Mialhe, J-L Zambonino-Infante, G. Koumoundouros
Summary: This study examines the recovery of juvenile zebrafish from haemal lordosis and identifies the musculoskeletal mechanisms involved. The results show that 80% of the affected fish can recover within a week and several processes related to chromosome organization, DNA replication, circadian clock and transcription regulation play key roles in this recovery procedure.
SCIENTIFIC REPORTS
(2022)
Article
Environmental Sciences
Petek Piner Benli, Mehmet Celik
Summary: This study found that acute exposure to sulfoxaflor significantly increased AChE enzyme activity in the brain and muscle tissues of zebrafish, with induction percentages ranging from 10% to 83% and 19% to 79%, respectively.
Article
Engineering, Marine
Hugo C. Vieira, Andreia C. M. Rodrigues, Amadeu M. V. M. Soares, Sizenando Abreu, Fernando Morgado
Summary: The study found that mercury accumulation in the liver of zebrafish exposed to mercury-contaminated food was faster compared to other tissues, while the gills exhibited the fastest depuration rate. The bioaccumulation factor values of mercury in the liver and muscle increased linearly during the uptake period, indicating that zebrafish needed more than 4 weeks to depurate mercury effectively. The distribution of mercury in the water column also showed differences between the accumulation and depuration periods.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2021)
Article
Genetics & Heredity
Xiangqi Zhong, Jiaze Gu, Siying Zhang, Xiangning Chen, Jingjing Zhang, Jintao Miao, Zhujin Ding, Jianhe Xu, Hanliang Cheng
Summary: In this study, a diet-induced obesity model was developed in zebrafish to investigate the impact of peripheral 5-HT on muscle tissue transcription characteristics. The results demonstrated that peripheral 5-HT affected body weight and gene expression in metabolic pathways related to muscle metabolism in zebrafish.
Article
Marine & Freshwater Biology
Kaden K. Fujita, Zhe Xia, Gregg Tomy, Tony Montina, Steve Wiseman
Summary: Studies have shown that exposure to sediment derived water-soluble fraction of dilbit can have adverse effects on zebrafish embryos, leading to increased prevalence of pericardial edema, yolk sac edema, and swim bladder malformations. Analysis of altered metabolites revealed potential impacts on four metabolic pathways, providing insights into the mechanisms underlying the developmental effects observed in embryos. Future research should further investigate the specific role of these perturbed metabolites and pathways in the adverse effects of dilbit exposure.
AQUATIC TOXICOLOGY
(2021)
Article
Environmental Sciences
Larissa Lechinovski, Mayomie Bados, Jonathan Rosa, Deise Borchhardt Moda, Ana Carolina de Deus Bueno Krawczyk
Summary: The contamination of aquatic environments has increased over time, affecting both the environment and human health. This study compared the ecotoxicological effects of conventional herbicides (Atrazine and Glyphosate) and a natural herbicide on Zebrafish. The results showed that the conventional herbicides caused more nuclear abnormalities in the fish and had a higher mutagenic potential, while the natural herbicide had lower toxicity and was less harmful to the fish. Therefore, natural herbicides could be a better option for environmental preservation.
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES
(2022)
Article
Behavioral Sciences
Jonathan J. Carver, Skyler C. Carrell, Matthew W. Chilton, Julia N. Brown, Lengxob Yong, Yong Zhu, Fadi A. Issa
Summary: Aggression is a fundamental behavior in animal species, but excessive or insufficient aggression can have negative consequences for individuals and group members. Research has shown the importance of nuclear steroid hormone receptors in regulating aggressive behaviors in male zebrafish.
HORMONES AND BEHAVIOR
(2021)
Article
Environmental Sciences
Huiyuan Xue, Yefeng Zhang, Na Chen, Han Gao, Qixuan Zhang, Shengri Li, Wentao Yu, Tianzi Wang, Fajian Luo, Fengmei Cui, Jun Wan, Yu Tu, Liang Sun
Summary: The release of liquid effluent from nuclear power plants into aquatic systems has been increasing, prompting the need for studying its effects on aquatic organisms. Zebrafish were used to create models to investigate radiation damage and dose rates, with the study finding differences in internal and external dose coefficients of various organs, and highlighting Sr-90 as a significant contributor. Male and female zebrafish showed varying levels of external dose coefficients in their hearts and gonads compared to the whole body, emphasizing the importance of refined modeling for assessing radiation effects on non-human species.
JOURNAL OF ENVIRONMENTAL RADIOACTIVITY
(2021)
Article
Endocrinology & Metabolism
Sheridan J. C. Baker, Emily Corrigan, Nicholas Melnyk, Renee Hilker, Glen Van der Kraak
Summary: This study investigates the expression of Pgr in zebrafish ovarian follicles and its downstream targets, revealing that Pgr plays a critical role in ovulation by controlling the expression of genes like ptger4a, ptger4b, and pla2g4a. Results suggest that Pgr is involved in prostaglandin production and function by regulating PLA2G4A and receptor EP4b expression, which are influenced by the actions of 17,20-beta-P.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2021)
Article
Physiology
Rosa M. Keller, Laura M. Beaver, Patrick N. Reardon, Mary C. Prater, Lisa Truong, Matthew M. Robinson, Robyn L. Tanguay, Jan F. Stevens, Norman G. Hord
Summary: Dietary nitrate supplementation can improve exercise performance by reducing the oxygen cost of exercise and enhancing skeletal muscle function. The study showed that nitrate exposure in zebrafish model upregulated key nutrient-sensing genes, leading to greater availability of energy-producing metabolites. Overall, nitrate supplementation may lower the oxygen cost of exercise through metabolic programming of muscle prior to exercise.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Cell Biology
Nilay Taneja, Sophie M. Baillargeon, Dylan T. Burnette
Summary: MLCK promotes turnover of MII at the mitotic cortex, leading to altered phosphorylation levels of RLC and increased cortex tension, which drives membrane bleb formation and growth, but reduces bleb retraction during mitosis.
MOLECULAR BIOLOGY OF THE CELL
(2021)
Article
Fisheries
Honghui Li, Niyokwizera Isaac, Shuwen He, Xiaohui Ou, Jing Xiang, Xing Tian, Haojie Zhu, Li Liu, Li Wen, Wuying Chu
Summary: The study demonstrates that dietary supplementation with P. clarkii shell protein hydrolysates can significantly improve growth performance and muscle health of zebrafish, enhance antioxidant capacity, and regulate the expression of circadian clock genes.
AQUACULTURE REPORTS
(2022)
Article
Developmental Biology
Roberto Moreno-Ayala, Denhi Schnabel, Enrique Salas-Vidal, Hilda Lomeli
DEVELOPMENTAL BIOLOGY
(2015)
Review
Biochemistry & Molecular Biology
Hilda Lomeli, Jorge Castillo-Robles
Meeting Abstract
Developmental Biology
Mario Mendieta-Serrano, Francisco Javier Mendez-Cruz, Luis Cardenas, Mayra Antunez-Mojica, Laura Alvarez, Denhi Schnabel-Peraza, Hilda Lomeli, Enrique Salas-Vidal
MECHANISMS OF DEVELOPMENT
(2017)
Article
Anatomy & Morphology
Mario A. Mendieta-Serrano, Denhi Schnabel, Hilda Lomeli, Enrique Salas-Vidal
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY
(2013)
Article
Multidisciplinary Sciences
Jorge Castillo-Robles, Laura Ramirez, Herman P. Spaink, Hilda Lomeli
SCIENTIFIC REPORTS
(2018)
Article
Biochemistry & Molecular Biology
Mario A. Mendieta-Serrano, Francisco J. Mendez-Cruz, Mayra Antunez-Mojica, Denhi Schnabel, Laura Alvarez, Luis Cardenas, Hilda Lomeli, Juan A. Ruiz-Santiesteban, Enrique Salas-Vidal
FREE RADICAL BIOLOGY AND MEDICINE
(2019)
Article
Developmental Biology
Denhi Schnabel, Jorge Castillo-Robles, Hilda Lomeli
Review
Anatomy & Morphology
Hilda Lomeli, Francisco Castillo-Castellanos
DEVELOPMENTAL DYNAMICS
(2020)
Article
Developmental Biology
Palacios-Martinez Janet, Caballero-Perez Juan, Espinal-Centeno Annie, Marquez-Chavoya Gilberto, Lomeli Hilda, Salas-Vidal Enrique, Schnabel Denhi, Chimal-Monroy Jesus, Cruz-Ramirez Alfredo
DEVELOPMENTAL BIOLOGY
(2020)
Article
Cell Biology
Rachna Narayanan, Mario A. Mendieta-Serrano, Timothy E. Saunders
Summary: Tissue remodelling and organ shaping during morphogenesis are influenced by mechanical forces generated at the cellular level, which can be coordinated through biochemical and mechanical cues across the tissue. This coordination leads to the generation of complex tissue shape during morphogenesis, as demonstrated in vertebrate axis morphogenesis, using examples from post gastrulation development of the zebrafish embryo.
CURRENT OPINION IN CELL BIOLOGY
(2021)
Review
Genetics & Heredity
Hilda Lomeli
Summary: ZMIZ1 and ZMIZ2 are coregulator proteins that interact with transcription factors and play important roles in embryonic development and human diseases. They have diverse functions and can stimulate the activity of various signaling pathways, as well as interact with chromatin remodeling complexes. Understanding the associations between the function of ZMIZ coregulators and human pathologies could lead to the development of new drug targets for diseases such as hormone-dependent cancers.
JOURNAL OF MOLECULAR MEDICINE-JMM
(2022)
Article
Cell Biology
Mario A. Mendieta-Serrano, Sunandan Dhar, Boon Heng Ng, Rachna Narayanan, Jorge J. Y. Lee, Hui Ting Ong, Pearlyn Jia Ying Toh, Adrian Rollin, Sudipto Roy, Timothy E. Saunders
Summary: The process of skeletal myogenesis involves dynamic changes in cell shape, fusion, and rearrangement, leading to the organized structure of striated fibers. Through live imaging and quantitative analysis in zebrafish, the fusion of fast-twitch myocytes within the myotome was studied. It was found that fusion timing had a strong medial-lateral bias, while at the cellular scale, there was heterogeneity in cell shape and the relationship between initial position and fusion partners. The study suggests that slow muscle rearrangement guides the fusion of fast myocytes, enhancing fusion probability and contributing to the emergence of a robust myotome structure.
DEVELOPMENTAL CELL
(2022)
Article
Developmental Biology
Jeronimo Roberto Miranda-Rodriguez, Enrique Salas-Vidal, Hilda Lomeli, Mario Zurita, Denhi Schnabel
DEVELOPMENTAL BIOLOGY
(2017)
Article
Developmental Biology
Sanjana Srinivasan, Xinjian He, Sarah Mirza, Jesse Mager
Summary: Exosome Complex Components 1 and 2 (EXOSC1 and 2) are essential proteins in the RNA Exosome complex that play important roles in early mammalian development. Their absence results in developmental delay and morphological abnormalities in embryos.
GENE EXPRESSION PATTERNS
(2024)