Three molecular pathways model colorectal carcinogenesis in Lynch syndrome

Mismatch repair deficiency commonly precedes adenoma formation in Lynch Syndrome-Associated colorectal tumorigenesis

(2017) Shigeki Sekine et al.   MODERN PATHOLOGY

Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas

(2017) Moritz Jesinghaus et al.   MODERN PATHOLOGY

CTNNB1-mutant colorectal carcinomas with immediate invasive growth: a model of interval cancers in Lynch syndrome

(2016) Aysel Ahadova et al.   Familial Cancer

Copy number changes of clinically actionable genes in melanoma, non-small cell lung cancer and colorectal cancer-A survey across 822 routine diagnostic cases

(2016) Nicole Pfarr et al.   GENES CHROMOSOMES & CANCER

Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology

(2016) Moritz Jesinghaus et al.   GENES CHROMOSOMES & CANCER

Mismatch repair deficiency in Lynch syndrome-associated colorectal adenomas is more prevalent in older patients

(2016) Masahiro Tanaka et al.   HISTOPATHOLOGY

Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma

(2016) Marios Giannakis et al.   Cell Reports

E-cadherin can limit the transforming properties of activating  -catenin mutations

(2015) D. J. Huels et al.   EMBO JOURNAL

Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer

(2015) Michael Kloth et al.   GUT

Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database

(2015) Pål Møller et al.   GUT

Association Between Specific Mutations inKRASCodon 12 and Colorectal Liver Metastasis

(2015) Georgios Antonios Margonis et al.   JAMA Surgery

Mismatch repair deficient-crypts in non-neoplastic colonic mucosa in Lynch syndrome: insights from an illustrative case

(2014) Jinru Shia et al.   Familial Cancer

RNF43 is frequently mutated in colorectal and endometrial cancers

(2014) Marios Giannakis et al.   NATURE GENETICS

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

(2013) Tomer Cooks et al.   CANCER CELL

Somatic Mutations in MLH1 and MSH2 Are a Frequent Cause of Mismatch-Repair Deficiency in Lynch Syndrome-Like Tumors

(2013) Arjen R. Mensenkamp et al.   GASTROENTEROLOGY

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

(2013) Hans F A Vasen et al.   GUT

Colorectal cancer

(2013) Hermann Brenner et al.   LANCET

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Microsatellite Instability and DNA Mismatch Repair Protein Deficiency in Lynch Syndrome Colorectal Polyps

(2012) M. B. Yurgelun et al.   Cancer Prevention Research

Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study

(2012) Matthias Kloor et al.   LANCET ONCOLOGY

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry

(2012) Michael D Walsh et al.   MODERN PATHOLOGY

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Molecular Genetics of Colorectal Cancer

(2011) Eric R. Fearon   Annual Review of Pathology-Mechanisms of Disease

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Hereditary and Familial Colon Cancer

(2010) Kory W. Jasperson et al.   GASTROENTEROLOGY

Microsatellite Instability in Colorectal Cancer

(2010) C. Richard Boland et al.   GASTROENTEROLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

In Lynch syndrome adenomas, loss of mismatch repair proteins is related to an enhanced lymphocytic response

(2009) Tineke W H Meijer et al.   HISTOPATHOLOGY

Familial adenomatous polyposis

(2009) Elizabeth Half et al.   Orphanet Journal of Rare Diseases

Prevalence of Adenomas and Hyperplastic Polyps in Mismatch Repair Mutation Carriers Among CAPP2 Participants: Report by the Colorectal Adenoma/Carcinoma Prevention Programme 2

(2008) Annelie Liljegren et al.   JOURNAL OF CLINICAL ONCOLOGY