Article
Polymer Science
Andreea Miron, Andrei Sarbu, Anamaria Zaharia, Teodor Sandu, Horia Iovu, Radu Claudiu Fierascu, Ana-Lorena Neagu, Anita-Laura Chiriac, Tanta-Verona Iordache
Summary: This study introduces a method for extracting calcium-carbonate-enriched chitosan from shrimp shell waste, aiming to improve its performance, and successfully provides chitosan products with high deacetylation degree and excellent thermal stability.
Article
Environmental Sciences
G. Issabayeva, S. H. Wong, C. Y. Pang, M. C. Wong, M. K. Aroua
Summary: This study evaluated the adsorption of fluoride using two low-cost adsorbents: palm shell activated carbon and chitosan of prawn shells. The highest removal efficiencies of fluoride by the adsorbents were 46% and 55% at pH 2 and 7, respectively. The contrasting behavior of the two adsorbents in relation to pH is attributed to the surface charge associated with surface functional groups identified by FTIR. Adsorption kinetics results fitted well into the pseudo-second-order kinetics model, suggesting a chemisorption mechanism of fluoride removal.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL SCIENCE AND TECHNOLOGY
(2022)
Article
Energy & Fuels
P. A. Aneesh, R. Anandan, Lekshmi R. G. Kumar, K. K. Ajeeshkumar, K. Ashok Kumar, Suseela Mathew
Summary: Management of waste generated in fish processing industries is a global concern. This study utilized biorefinery technology to convert shrimp processing waste into commercially important products such as astaxanthin-rich oil, protein, chitin, and chitosan.
BIOMASS CONVERSION AND BIOREFINERY
(2023)
Article
Agriculture, Multidisciplinary
Joanna Tkaczewska, Piotr Kulawik, Ewelina Jamroz, Martina Cagalj, Roberta Frleta Matas, Vida Simat
Summary: This study developed a technology to use waste from prawn and shrimp processing as a source of active ingredients for healthy foods. The obtained protein hydrolysates from prawn and shrimp shells were characterized for their protein content, degree of hydrolysis, and antioxidant and antimicrobial activity. The hydrolysate with the best antioxidant properties was selected and tested for its potential use in functional foods. Furthermore, the possibility of using carotenoproteins from prawn waste to form emulsions was investigated.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Chemistry, Physical
Zhanyong Wang, Tingting Su, Jingjing Zhao
Summary: The utilization of genipin-crosslinked chitosan beads as a carrier for immobilizing recombinant cutinase from Fusarium solani (FSC) resulted in improved thermal and pH stability of the enzyme, enhancing its performance for industrial applications.
Article
Chemistry, Applied
Fatima-ezzahra Ettoumi, Ruyuan Zhang, Yanqun Xu, Li Li, Hao Huang, Zisheng Luo
Summary: This study aimed to improve the thermodynamic performance of nanoliposomes (NLs) by using a second-layer coating biopolymer, fucoidan (F), along with chitosan (CS), to control the delivery and bioavailability of catechin (C) and juglone (J). The developed F/CS-conjugated JC-NL (F-CS-JC-NL) showed enhanced stability under different pH and ionic strengths, and had the highest encapsulation efficiency of juglone (95.47%) and catechin (90.88%). In vitro digestion experiments demonstrated that F-CS-JC-NL significantly reduced compound leakage in the gastrointestinal tract and provided better controlled release and bioavailability of juglone/catechin compared to other formulations. This study provides a novel nanoliposomal delivery carrier with enhanced physicochemical stability and controlled release for delivering functional ingredients.
Article
Chemistry, Multidisciplinary
Dingdong Yuan, Yu Zhang, King Hoo Lim, Stephen King Pong Leung, Xizi Yang, Yujie Liang, Wilson Chun Yu Lau, Kwan T. Chow, Jiang Xia
Summary: This study reports a peptide-guided, proximity-driven group transfer reaction for site-selective acetylation of a single lysine residue in IgG. The reaction proceeded efficiently under physiological conditions without the need for deglycosylation or catalysts, allowing further derivatization of IgG. The method was also used to synthesize antibody-lipid conjugates and antibody-conjugated liposomes for targeted cancer cell therapy. Additionally, a bispecific antibody complex showed potent in vitro cytotoxicity at nanomolar concentrations.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Engineering, Chemical
Wei Pan, Yucheng Yang, Daomao Yang, Moses Arowo, Shuai Wu, Yingjie He, Qingyou Zeng
Summary: Efficient waste management is important for society, and this study developed a two-stage circular process for the utilization of waste bittern and discarded oyster shells. The results showed high yields of MgCO3•3H2O and a high regeneration ratio of R3N. This work provides a sustainable solution to environmental pollution and suggests a promising avenue for green chemical production.
Article
Biochemistry & Molecular Biology
Gautham Devendrapandi, Deepakrajasekar Padmanaban, Rabi Thanikasalam, Anthoniammal Panneerselvam, Ragasudha Palraj, Jothi Ramalingam Rajabathar, Nagappan Rajendiran, Ranjith Balu, Tae Hwan Oh, Subramaniyan Ramasundaram
Summary: The use of marine waste-derived chitosan (CS) for the synthesis of nanomaterials is effective for bio-waste management and recovering functional products. CS capped silver nanoparticles (Ag NPs-CS) were synthesized using shrimp shell waste and exhibited potential anticancer and dye pollutants adoption properties. The CS-Ag NPs showed anticancer activity against human lung adenocarcinoma cell lines and degradation of mixed dye target solution, suggesting their potential biomedical and environmental applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Vishwapriya Saravanan, Mubarakali Davoodbasha, Arjun Rajesh, Thajuddin Nooruddin, Sang-Yul Lee, Jung-Wan Kim
Summary: This study investigated the biological activity of chitosan extracted from Borassus flabellifer fruit shells and analyzed its molecular structure using FT-IR analysis. The results showed that chitosan exhibited antibacterial activity against E. coli and S. aureus and also had potential as an antioxidant polymer.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Yan-Wei Liu, Ying Zhou, Guo-Qing Huang, Li-Ping Guo, Xiao-Dan Li, Jun-Xia Xiao
Summary: Coacervation of lipase with chitosan was a viable method to fabricate lipase-loaded particles. Optimum conditions were achieved at pH 5.5, chitosan to lipase mass ratio of 1:5, and temperature of 25 degrees C without NaCl. Coacervation increased the activity of lipase and shifted its optimum pH from 7.0 to 6.0, while maintaining the optimum temperature at 45 degrees C.
Article
Food Science & Technology
C. S. Liyanage, S. T. Gonapinuwala, C. A. N. Fernando, M. D. S. T. de Croos
Summary: A modified method of chitosan extraction from crustacean shell waste was developed using single-step alkali steeping. Yield percentages of chitosan obtained from different crustaceans were 33.26%, 11.39%, and 10.15% for whiteleg shrimp, blueswimming crab, and giant freshwater prawns, respectively. The modified method preserved physicochemical properties and showed potential for industrial implementation with energy and chemical savings of 13% and 8.10%, respectively, compared to the conventional heating method.
JOURNAL OF AQUATIC FOOD PRODUCT TECHNOLOGY
(2023)
Article
Polymer Science
Akanksha Patel, Allen C. Chang, Abigail Mastromonaco, Mauricio Acosta Diaz, Sarah Perry, Olivia Ferki, Christian Ayafor, Umer Abid, Hsi-Wu Wong, Dongming Xie, Margaret J. Sobkowicz
Summary: This study explores the complex relationship between kinetics and substrate morphology during enzymatic depolymerization of PET and analyzes the effects of competing transformations. The presence of water was found to play an important role in plasticization and crystallization of PET. It suggests that the rate of depolymerization of PET substrates is crucial for achieving high conversion to monomeric product.
Article
Engineering, Chemical
Abu Naser Md Ahsanul Haque, Maryam Naebe, Debbie Mielewski, Alper Kiziltas
Summary: This study proposes a method of converting waste wool into thermally stable micro-sized silica-modified powder through controlled chemical treatment. The chemically prepared powder showed significant improvement in thermal stability and crystalline structure compared to mechanically prepared powder. This research reveals an innovative method for transforming waste wool with potential applications in various industries.
Article
Chemistry, Physical
Fariba Malekpour Galogahi, Hongjie An, Yong Zhu, Nam-Trung Nguyen
Summary: This study investigates the behavior of core-shell microparticles with a liquid core under thermal and mechanical loads, establishing analytical models and conducting experiments to validate them. The results demonstrate that the maximum temperature and critical compression force before rupture of core-shell microparticles depend on the liquid, geometry, and material of the shell.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)