Article
Multidisciplinary Sciences
Qian-hui Tang, Jing Chen, Zhen Long, Yu-Lin Wang, Xuan-an Su, Jian-ye Qiu, Qiu-ning Lin, Jiang-feng Zhang, Xiao Qin
Summary: This study aimed to investigate the factors influencing distal false lumen enlargement after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection. The results revealed that Marfan syndrome, chronic obstructive pulmonary disease (COPD), and the primary tear size were associated with distal false lumen dilatation.
Article
Surgery
Louis P. Parker, Benedikt Reutersberg, Maaz B. J. Syed, Bijit Munshi, Samantha Richards, Lachlan J. Kelsey, Natzi Sakalihasan, Hans-Henning Eckstein, Paul E. Norman, Barry J. Doyle
Summary: This study found that proximal false lumen thrombosis is associated with reduced false lumen pressure and a lower incidence of acute complications and adverse aortic events within the first year.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Kyle G. Miletic, Bogdan A. Kindzelski, Kevin E. Hodges, Jocelyn Beach, Michael Z. Tong, Faisal Bakaeen, Douglas R. Johnston, Milind Desai, Sean Lyden, Eric E. Roselli
Summary: Retrograde false lumen perfusion after thoracic endovascular aortic repair for chronic dissection is a mode of treatment failure, while thrombosis of the false lumen is associated with favorable reverse remodeling. Embolization strategy can promote aortic remodeling. After embolization, most patients experienced decreased aortic diameter, increased true lumen diameter, and decreased false lumen diameter.
ANNALS OF THORACIC SURGERY
(2021)
Review
Surgery
Hai -Lei Li, Yiu Che Chan, He-Yue Jia, Stephan W. Cheng
Summary: FL embolization of the distal thoracic aorta is a promising technique to promote FL thrombosis and aortic remodeling in a group of patients with thoracic aortic dissection.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Surgery
Alexander Massmann, Christian Giebels, Arno Buecker, Hans-Joachim Schafers, Peter Fries
Summary: This case report presents percutaneous endovascular rescue techniques for unintended false-lumen thoracic endovascular aortic repair. The techniques successfully restored true-lumen perfusion and preserved visceral and peripheral perfusion.
JOURNAL OF ENDOVASCULAR THERAPY
(2022)
Article
Biotechnology & Applied Microbiology
Alireza Jafarinia, Chloe H. Armour, Richard G. J. Gibbs, Xiao Yun Xu, Thomas Hochrainer
Summary: Type B aortic dissection is a dangerous condition with high mortality rates, characterized by the separation of aortic wall layers due to an intimal tear. Complete thrombosis of the false lumen is crucial for improving clinical outcomes. Local false lumen hemodynamics play an essential role in thrombus formation.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Anfeng Yu, Min Zhang, Zhiwei Wang, Zhipeng Hu, Rui Hu, Qiubei Xiao
Summary: This study investigated the clinical outcomes of elephant trunk stent fenestration in ATAAD patients, showing that this technique can reduce surgical difficulty and lead to a high postoperative survival rate.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Patrick R. Vargo, Jean-Luc Maigrot, Eric E. Roselli
Summary: This study used false lumen embolization technique to treat chronic aortic dissection, showing no mortality, stroke, spinal cord ischemia, visceral or limb ischemia after the procedure.
ANNALS OF CARDIOTHORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Heng Zhang, Jiaxuan Feng, Hongqiao Zhu, Shun Xiao, Mingyuan Liu, Yili Xu, Dongshan Yang, Junjun Liu, Mingjin Guo
Summary: This study evaluates the feasibility, efficacy, and safety of using a single-branched stent-graft with on-table fenestration for primary retrograde type A aortic dissection (RTAD) during thoracic endovascular aortic repair (TEVAR). The results show that after medical management in the acute phase, the retrograde false lumen (FL) can achieve partial or complete thrombosis, and using a single-branched stent graft with on-table fenestration in the subacute phase may be a feasible strategy for selective primary RTAD patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Surgery
Heepeel Chang, Caron B. Rockman, Neal S. Cayne, Frank J. Veith, Glenn R. Jacobowitz, Jeffrey J. Siracuse, Virendra Patel, Karan Garg
Summary: The study suggests that anticoagulation and antiplatelet medications do not negatively influence midterm outcomes such as aortic reintervention or death in patients undergoing TEVAR for type B aortic dissection. It also does not impair complete false lumen thrombosis.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Surgery
Min Zhou, Fei Liu, Xiaolong Shu, Zhenyu Shi, Daqiao Guo, Lixin Wang, Weiguo Fu
Summary: The new SS-FLEVOR technique, combining spot stenting and false lumen endovascular occlusive repair, has shown to be effective in treating post-dissection abdominal aortic aneurysms with 100% technical success in 5 patients and encouraging intermediate outcomes.
JOURNAL OF ENDOVASCULAR THERAPY
(2022)
Article
Surgery
Marek K. Kuzniar, Anders Wanhainen, Gustaf Tegler, Kevin Mani
Summary: The study reported short- and midterm outcomes of chronic aortic dissection patients treated with F/B-EVAR at a vascular center. The procedures had high success rates but some complications and reinterventions occurred.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Melissa M. Levack, Bogdan A. Kindzelski, Kyle G. Miletic, Patrick R. Vargo, Faisal G. Bakaeen, Douglas R. Johnston, Jeevanantham Rajeswaran, Eugene H. Blackstone, Eric E. Roselli
Summary: Adjunctive balloon fracture fenestration (BFF) during thoracic endovascular aortic repair (TEVAR) can improve the outcomes of chronic thoracic aortic dissection complicated by negative remodeling. The results of this study showed that BFF can effectively reduce aortic diameter, increase true lumen diameter, and promote thrombus formation.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Surgery
Dongqiao Xiang, Bin Chai, Yuxi Gui, Jia Huang, Huimin Liang, Bin Liang, Huangxuan Zhao, Fan Yang, Chuansheng Zheng
Summary: This study investigated the risk factors for distal stent graft-induced new entry (dSINE) in patients with uncomplicated type B aortic dissection (TBAD) who underwent thoracic endovascular aortic repair. It was found that a type III aortic arch, decreased angle, increased distal oversizing, and increased distal mismatch ratio were significant risk factors for dSINE. The use of a tapered stent graft with a >4-mm taper could prevent dSINE, and aggressive reintervention for dSINE led to favorable long-term outcomes.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Surgery
Diletta Loschi, Annarita Santoro, Enrico Rinaldi, Claudia Anselmi, Camilla Grignani, Roberto Chiesa, Germano Melissano
Summary: This study investigates the types and outcomes of thoracic endovascular aneurysm repair and Candy Plug (CP) implantation for type B aortic dissection. The CP technique is found to be safe and effective, but there is a significant rate of aortic-related reintervention and high rate of major complications in open repair.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Medicine, General & Internal
Zhonghua Sun, Curtise K. C. Ng
Summary: The use of an advanced artificial intelligence model to suppress blooming artifacts in computed tomography angiography can improve the diagnostic performance for calcified plaques in the coronary artery.
Article
Radiology, Nuclear Medicine & Medical Imaging
Chloe Dann, Zhonghua Sun
Summary: Medical imaging plays a crucial role in managing patients with COVID-19. The pandemic has impacted the practice and workplace of medical imaging professionals, with concerns including inadequate access to personal protective equipment, decreased imaging volume, and lack of psychological support. Efforts should be made to support staff members and ensure adequate PPE supplies.
JOURNAL OF MEDICAL RADIATION SCIENCES
(2022)
Article
Medicine, General & Internal
Chunyan Shi, Hongkai Zhang, Nan Zhang, Dongting Liu, Zhanming Fan, Zhonghua Sun, Jiayi Liu, Lei Xu
Summary: This study used 7.0T CMR to investigate the dynamic characteristics of myocardial strain and altered extracellular volume (ECV) in T2DM mice. The results showed that T2DM mice had significantly higher ECV and impaired myocardial strain. There was a significant linear correlation between myocardial strain and ECV, as well as left ventricular ejection fraction and ECV. This study provides insights into the functional abnormalities associated with ECM alterations in diabetic cardiomyopathy and the effects of diabetic therapy.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Analytical
Jade Geerlings-Batt, Carley Tillett, Ashu Gupta, Zhonghua Sun
Summary: This study developed a novel teaching tool using augmented reality and 3D printed models to accurately demonstrate normal ankle and foot anatomy. While the segmentation outcomes were sufficient, the object recognition function did not work as intended, and the reproducibility of this method is limited.
Review
Chemistry, Analytical
Zhonghua Sun, Cleo Wee
Summary: 3D printing technology has shown great potential in medical applications, particularly in the diagnosis and surgical planning of cardiovascular diseases.
Review
Chemistry, Multidisciplinary
Elizabeth Arthur, Zhonghua Sun
Summary: This review analyzed the literature on the use of eye-tracking equipment in the evaluation of radiological image interpretation. The majority of the literature focused on competency assessment of professionals, with conflicting results in terms of speed and eye-metrics. While eye-tracking as an educational tool was suggested to improve educational repertoire and interpretation technique, the literature on visual search behavior analysis and evaluation of assistive aids did not provide strong conclusions due to research limitations.
APPLIED SCIENCES-BASEL
(2022)
Article
Medicine, General & Internal
Jade Geerlings-Batt, Ashu Gupta, Zhonghua Sun
Summary: This study retrospectively reviewed the coronary computed tomography angiography datasets and CAD risk factor checklists of 250 patients, and found a relationship between narrow RCA-aorta angles and CAD, smoking, and increasing BMI.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Yan Chen, Wenjing Zhao, Nan Zhang, Jiayi Liu, Dongting Liu, Zhonghua Sun, Lei Xu, Zhaoying Wen
Summary: This retrospective study aims to assess the variation in left atrial and biventricular strain and its prognostic value in suspected myocarditis. The results showed that the left atrial total emptying fraction was the only functional index that showed a statistically significant improvement, and the initial left atrial peak's late negative strain rate was the only parameter with significant predictive power of major adverse cardiac events. Therefore, cardiac magnetic resonance strain has great potential for monitoring left atrial and ventricular function in suspected myocarditis.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Anatomy & Morphology
Morgan Titmus, Gary Whittaker, Milo Radunski, Paul Ellery, Beatriz I. R. de Oliveira, Hannah Radley, Petra Helmholz, Zhonghua Sun
Summary: This study has developed a semi-standardized photogrammetry workflow to produce photorealistic 3D models of human specimens. The described technique successfully digitized eight specimens, preserving their geometry and texture and providing novel educational experiences.
JOURNAL OF ANATOMY
(2023)
Review
Chemistry, Analytical
Zhonghua Sun, Yin How Wong, Chai Hong Yeong
Summary: This article presents the experience of using a 3D-printing facility to print patient-specific low-cost models for various medical applications. These models include personalized models of cardiovascular diseases and tumors, as well as novel 3D-printed models for simulating breast cancer MRI and calcified coronary plaques. CT scanning confirmed the high accuracy of these models in replicating anatomy and pathology in different body regions at affordable costs. The experience highlights the feasibility of utilizing 3D-printing technology in medical education and clinical practice.
Article
Medicine, General & Internal
Nan Zhang, Xin Zhao, Jie Li, Liqun Huang, Haotian Li, Haiyu Feng, Marcos A. A. Garcia, Yunshan Cao, Zhonghua Sun, Senchun Chai
Summary: A fully automatic framework based on machine learning was developed for pulmonary artery pressure assessment using CTPA images. It accurately segmented the pulmonary artery and heart, and automatically assessed the PAP parameters. It has the ability to accurately distinguish different patients with pulmonary hypertension.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Xuelian Gao, Rui Wang, Zhonghua Sun, Hongkai Zhang, Kairui Bo, Xiaofei Xue, Junjie Yang, Lei Xu
Summary: This study found that the CTP-FFR model has promising value in improving the diagnostic accuracy of CCTA in detecting coronary ischemia. The feasibility of using CTP-FFR to detect coronary artery ischemia in patients with suspected CAD was proven.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Pediatrics
Zhonghua Sun
Summary: Three-dimensional (3D) printing technology is increasingly used in the medical field, especially in the area of cardiovascular disease. It offers superior advantages over standard image visualizations and current diagnostic approaches. Patient-specific 3D printed models are particularly valuable in comprehending cardiovascular anatomy and pathology. This review provides an overview of the educational value and clinical applications of 3D-printed models in pediatric congenital heart disease, highlighting the importance of communication and future research directions.
Review
Chemistry, Multidisciplinary
Timothy Rossi, Ally Williams, Zhonghua Sun
Summary: Patient-specific 3D-printed liver models (3DPLMs) reconstructed from medical imaging data can enhance the comprehension of patient liver anatomy and provide useful tools for preoperative planning and intraoperative guidance. Current studies demonstrate that 3DPLMs can strengthen decision making for liver cancer resection (LCR) but further research and clinical trials are needed to confirm their value and assess economic factors.
APPLIED SCIENCES-BASEL
(2023)
Review
Biochemistry & Molecular Biology
Zhonghua Sun, Jack Zhao, Emily Leung, Maria Flandes-Iparraguirre, Michael Vernon, Jenna Silberstein, Elena M. De-Juan-Pardo, Shirley Jansen
Summary: Three-dimensional (3D) printing is important in cardiovascular disease for its ability to create personalized models that accurately replicate the anatomy and pathology. 3D bioprinting further advances this technology by printing cellular or biological components, functional tissues and organs for use in cardiovascular applications. This review provides an overview of the use of 3D bioprinting in cardiovascular disease, focusing on cardiac tissues, vascular constructs, grafts, heart valves, and myocardium, and highlights limitations and future research directions.