Journal
INTERNAL MEDICINE
Volume 57, Issue 3, Pages 409-412Publisher
JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.8941-17
Keywords
Guillain-Barre syndrome; acute disseminated encephalomyelitis; encephalomyeloradiculoneuropathy; anti-galactocerebroside antibody; acute inflammatory; demyelinating polyneuropathy
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A 79-year-old woman with a history of Guillain-Barre syndrome (GBS) developed somnolence and tetraparesis after pneumonia. Based on clinical and laboratory findings, she was diagnosed with complications of acute inflammatory demyelinating polyneuropathy (AIDP) and acute disseminated encephalomyelitis (ADEM). Anti-galactocerebroside (Gal-C) IgG antibodies were detected in her serum. Cases of recurrent GBS in patients who are positive for this antibody are extremely rare. The anti-Gal-C IgG antibodies likely played an important role in the pathogenesis of the AIDP and ADEM.
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