4.2 Article

Bilateral Tuberculous Pleurisy with Subsequent Upper Lobe Predominant Pulmonary Fibrosis Mimicking Pleuroparenchymal Fibroelastosis

Journal

INTERNAL MEDICINE
Volume 57, Issue 1, Pages 85-89

Publisher

JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.9187-17

Keywords

tuberculous pleurisy; respiratory failure; pleuroparenchymal fibroelastosis; pleural effusion

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Although the majority of patients with Mycobacterium tuberculosis have pulmonary involvement, some cases have pleural involvement as extra-pulmonary sites of infection. We herein report a case of upper lobepredominant pulmonary fibrosis that developed in a 47-year-old male with a history of bilateral tuberculous pleurisy. Based on his chest radiological findings, pleuroparenchymal fibroelastosis (PPFE) was most strongly suspected, and a surgical lung biopsy (SLB) was performed to obtain a pathological diagnosis. The SLB specimens showed interstitial pneumonia with pleural involvement without any characteristic findings of PPFE. Careful discretion in obtaining a precise diagnosis of this condition should be practiced in such cases.

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