Article
Gastroenterology & Hepatology
Yuto Shimamura, Haruhiro Inoue, Enrique Rodriguez de Santiago, Mary Raina Angeli Abad, Yusuke Fujiyoshi, Akiko Toshimori, Mayo Tanabe, Kazuya Sumi, Yugo Iwaya, Haruo Ikeda, Manabu Onimaru, Miki Kushima, Kenichi Goda
Summary: This study aimed to evaluate the diagnostic yield of the fourth-generation EC for esophageal squamous lesions, revealing acceptable diagnostic accuracy and reliability in both experts and non-experts, especially when diagnosing SCC lesions.
DIGESTIVE ENDOSCOPY
(2021)
Article
Veterinary Sciences
Kathe Elise Kittelsen, Ingrid Toftaker, Fernanda Tahamtani, Randi Oppermann Moe, Ida Thofner, Guro Vasdal
Summary: The aim of this study was to estimate the sensitivity and specificity of palpation relative to necropsy for detection of keel bone fractures (KBF) in broiler breeders. The study found that palpation had poor diagnostic accuracy for detection of KBF and other methods, like necropsy, must be applied for reliable assessments.
Article
Gastroenterology & Hepatology
Sergei Vosko, Neal Shahidi, Mayenaaz Sidhu, W. Arnout van Hattem, Iddo Bar-Yishay, Scott Schoeman, David J. Tate, Luke F. Hourigan, Rajvinder Singh, Alan Moss, Karen Byth, Eric Y. T. Lee, Nicholas G. Burgess, Michael J. Bourke
Summary: This study found significant differences in optical evaluation performance between flat and nodular large nonpedunculated colorectal polyps. Flat lesions can be presumed benign and managed accordingly, while nodular lesions are more likely to be missed for submucosal invasive cancer.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Astronomy & Astrophysics
Travis A. Berger, Jennifer L. van Saders, Daniel Huber, Eric Gaidos, Joshua E. Schlieder, Zachary R. Claytor
Summary: Current spectroscopic surveys are generating extensive catalogs of chemical abundances for stars of various types. This study examines whether the yttrium-to-magnesium ratio [Y/Mg] can be used as an age indicator for FGK-type planet host stars observed by Kepler. The results show that the [Y/Mg] Clock is most accurate for solar twins, with a [Y/Mg]/age slope of m = -0.0370 +/- 0.0071 dex Gyr(-1) and a standard deviation of Age of 2.6 Gyr. The study also explores the relationship between [Y/Mg] and other stellar parameters such as effective temperature, surface gravity, and metallicity.
ASTROPHYSICAL JOURNAL
(2022)
Article
Gastroenterology & Hepatology
Adrien Patenotte, Clara Yzet, Timothee Wallenhorst, Fabien Subtil, Sarah Leblanc, Marion Schaefer, Thomas Walter, Thomas Lambin, Tanguy Fenouil, Pierre Lafeuille, Jean-Baptiste Chevaux, Romain Legros, Florian Rostain, Jerome Rivory, Jeremie Jacques, Vincent Lepilliez, Mathieu Pioche
Summary: This study evaluated the feasibility and effectiveness of ESD for lesions with a suspicion of focal deep invasion. It found that ESD is feasible and safe for colorectal lesions with an FDIP <= 15 mm. It achieved high resection and en bloc resection rates, making it a potential valid option for low-risk T1 cancer patients.
Article
Biochemistry & Molecular Biology
Alessandro Gambella, Chiara Pitino, Antonella Barreca, Alberto Nocifora, Manuela Maria Giarin, Luca Bertero, Luigi Biancone, Dario Roccatello, Mauro Papotti, Paola Cassoni
Summary: DNAJB9 as a diagnostic marker of FGN has high specificity and sensitivity, and its clinical application can greatly improve the efficiency and accuracy of FGN diagnosis.
Article
Biochemistry & Molecular Biology
Lianglu Zhang, Lanlan Dong, Changming Lu, Wenxian Huang, Cuiping Yang, Qian Wang, Ruixue Lei, Rui Sun, Kangkang Wan, Tingting Li, Fan Sun, Tian Gan, Jun Lin, Lei Yin
Summary: This study aimed to improve the sensitivity of SDC2 detection by identifying a high positive target TFPI2 from false-negative samples, showing that TFPI2 was hypermethylated in SDC2 hypomethylated colorectal cancer. The combined PCR assay of SDC2/TFPI2 significantly enhanced sensitivity in both tissue and stool samples, especially in detecting left colon lesions.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2021)
Article
Clinical Neurology
Yan Wu, Renqiang Ma, Qian Zhou, Ho Yin Lau, Yongquan Wang, Jian Li, Weiping Wen
Summary: The study found that the short daytime dexmedetomidine-induced PSG had good sensitivity and specificity for diagnosing OSA in adults, with changes in sleep architecture and posture observed during the test. No significant adverse events were reported.
Review
Gastroenterology & Hepatology
Devarshi R. Ardeshna, Troy Cao, Brandon Rodgers, Chidiebere Onongaya, Dan Jones, Wei Chen, Eugene J. Koay, Somashekar G. Krishna
Summary: Pancreatic cystic lesions (PCLs) are increasingly common due to more frequent abdominal imaging and an aging population. Accurate identification and risk stratification of PCLs are crucial for guiding treatment. However, current diagnostic testing is not optimal, leading to research on new techniques for differentiating and identifying high-risk PCLs for malignancy.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Immunology
Baihong Pan, Yaozhen Li, Yu Liu, Wei Wang, Gengwen Huang, Yang Ouyang
Summary: The study revealed that CitH3 concentration significantly increased in septic acute pancreatitis patients, and was closely correlated with disease severity and clinical outcomes. CitH3 may potentially serve as a diagnostic and prognostic biomarker for septic AP.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Meteorology & Atmospheric Sciences
Peter Uhe, Dann Mitchell, Paul D. Bates, Myles R. Allen, Richard A. Betts, Chris Huntingford, Andrew D. King, Benjamin M. Sanderson, Hideo Shiogama
Summary: Precipitation events are influenced by climate change, but different modeling approaches can lead to varying future projections. There is uncertainty in climate modeling which can greatly impact estimated precipitation changes. Confidence is higher in extreme precipitation changes compared to mean precipitation, highlighting the importance of considering multiple sources of climate projections.
JOURNAL OF CLIMATE
(2021)
Review
Biochemistry & Molecular Biology
Liudmila M. Mikhaleva, Rositsa A. Vandysheva, Konstantin Yu Midiber, Olesya A. Vasyukova, Valentina V. Pechnikova, Olga Patsap, Ozal Beylerli, Siva G. Somasundaram, Cecil E. Kirkland, Gjumrakch Aliev
Summary: Serrated colorectal lesions are a group of colonic lesions with premalignant potential, the current classification and diagnostic criteria depend on morphological, immunohistochemical, and molecular features, and further research is needed to develop more definitive markers.
CURRENT MEDICINAL CHEMISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Sharon Grad-Akrish, Adi Rachmiel, Ofer Ben-Izhak
Summary: The study found that SATB2 is not a reliable diagnostic marker for oral osteosarcoma, but it can be useful in detecting cells with osteoblast differentiation in histologic samples. Strong SATB2 expression was observed in juvenile aggressive ossifying fibroma, while weak expression was seen in stromal spindle cells adjacent to reactive bone tissue.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
(2021)
Article
Medicine, General & Internal
Xiao-Lin Lin, Dong-Sheng Zhang, Zhi-Ye Ju, Xiu-Ming Li, Yao-Zhu Zhang
Summary: This study aimed to explore the diagnostic efficacy of different ultrasonic examination methods in clinical endometrial lesions. The results showed that transvaginal color ultrasound had higher diagnostic coincidence rate and image display effect compared to transabdominal color ultrasound, with significant differences in endometrial thickness and blood flow among different types of lesions.
WORLD JOURNAL OF CLINICAL CASES
(2021)
Article
Oncology
Caroline Driescher, Katharina Fuchs, Lena Haeberle, Wolfgang Goering, Lisa Frohn, Friederike V. Opitz, Dieter Haeussinger, Wolfram Trudo Knoefel, Verena Keitel, Irene Esposito
Summary: This study demonstrated the feasibility and reliability of bile-derived cfDNA in the diagnosis of pancreatobiliary cancers, showing higher sensitivity compared to plasma and offering a potential alternative when tissue sampling is not feasible.
Article
Gastroenterology & Hepatology
Shin-ei Kudo, Yasuharu Maeda, Noriyuki Ogata, Masashi Misawa, Yushi Ogawa, Kazumi Takishima, Misaki Ishiyama, Kenichi Mochizuki, Yosuke Minegishi, Yohei Ogura, Masahiro Abe, Taishi Okumura, Shingo Matsudaira, Tomoyuki Ishigaki, Seiko Sasanuma, Yuichi Mori, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Toshiyuki Baba, Fumio Ishida, Tetsuo Nemoto, Shigeharu Hamatani, Kazuo Ohtsuka
Summary: This retrospective study aimed to demonstrate the diagnostic ability of combined endocytoscopy irregularly-formed nuclei with PIT (EC-IN-PIT) diagnosis to identify ulcerative colitis-associated neoplasias (UCAN). The results showed that EC-IN-PIT diagnosis had a significantly higher specificity and accuracy compared with PIT alone, especially in predicting UCAN with Mayo endoscopic score (MES) 0-1.
DIGESTIVE ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Misaki Ishiyama, Shin-ei Kudo, Masashi Misawa, Yuichi Mori, Yasuhara Maeda, Katsuro Ichimasa, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Fumio Ishida, Hayato Itoh, Masahiro Oda, Kensaku Mori
Summary: This study found that using CADe system for colonoscopy significantly increased the adenoma detection rate in a large-scale prospective evaluation, while there was no significant increase in the detection rate of advanced neoplasia.
GASTROINTESTINAL ENDOSCOPY
(2022)
Article
Mathematics
Masashi Misawa, Nobumitsu Nakauchi
Summary: This paper presents two examples of harmonic maps and p-harmonic ones into spheres of higher dimensions with specific singularities.
ADVANCES IN GEOMETRY
(2022)
Editorial Material
Gastroenterology & Hepatology
Shin-ei Kudo, Masashi Misawa, Yuichi Mori, Yurie Kawabata, Yasuharu Maeda, Hideyuki Miyachi, Kensaku Mori
Article
Gastroenterology & Hepatology
Diba Ainechi, Masashi Misawa, Ishita Barua, Solveig Linnea Veen Larsen, Vemund Paulsen, Kjetil Kjeldstad Garborg, Lars Aabakken, Christer Julseth Tonnesen, Magnus Loberg, Mette Kalager, Shin-Ei Kudo, Kinichi Hotta, Kazuo Ohtsuka, Shoichi Saito, Hiroaki Ikematsu, Yutaka Saito, Takahisa Matsuda, Hayato Itoh, Kensaku Mori, Michael Bretthauer, Yuichi Mori
Summary: The study showed that using AI tools for polyp detection significantly increased the sensitivity of early-career endoscopists, particularly in detecting neoplastic polyps.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2022)
Editorial Material
Gastroenterology & Hepatology
Amisha Ahuja, Yuichi Mori
Article
Gastroenterology & Hepatology
Yuichi Mori, Pu Wang, Magnus Loberg, Masashi Misawa, Alessandro Repici, Marco Spadaccini, Loredana Correale, Giulio Antonelli, Honggang Yu, Dexin Gong, Misaki Ishiyama, Shin-ei Kudo, Shunsuke Kamba, Kazuki Sumiyama, Yutaka Saito, Haruo Nishino, Peixi Liu, Jeremy R. Glissen Brown, Nabil M. Mansour, Seth A. Gross, Mette Kalager, Michael Bretthauer, Douglas K. Rex, Prateek Sharma, Tyler M. Berzin, Cesare Hassan
Summary: The use of AI during colonoscopy increases the proportion of patients needing intensive surveillance by approximately 35% in the United States and 20% in Europe. This contributes to improved cancer prevention but adds significant patient burden and healthcare costs.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Michael Bretthauer, Yuichi Mori, Jasmin Zessner-Spitzenberg, Michal F. F. Kaminski, Peter D. D. Siersema, Thierry Ponchon, Helmut Messmann, Ian M. M. Gralnek, Raf Bisschops, Cesare Hassan
Summary: The European Union has introduced stricter regulations for the approval of medical devices, affecting both endoscopists and patients. The new regulations require more clinical trials and observational studies to ensure the clinical benefit and reduce patient harm. The European Society of Gastrointestinal Endoscopy (ESGE) will play an active role in establishing the new system.
Meeting Abstract
Gastroenterology & Hepatology
Hideyuki Miyachi, Shinei Kudo, Yuta Kouyama, Katsuro Ichimasa, Shingo Matsudaira, Kenichi Mochizuki, Yuki Takashina, Yushi Ogawa, Maeda Yasuharu, Hiroki Nakamura, Masashi Misawa, Yuichi Mori, Noriyuki Ogata, Tomokazu Hisayuki, Toyoki Kudo, Takemasa Hayashi, Kunihiko Wakamura, Toshiyuki Baba, Tetsuo Nemoto, Fumio Ishida
GASTROINTESTINAL ENDOSCOPY
(2022)
Meeting Abstract
Gastroenterology & Hepatology
Yuichi Mori, Pu Wang, Magnus Loberg, Masashi Misawa, Alessandro Repici, Marco Spadaccini, Loredana Correale, Giulio Antonelli, Honggang Yu, Dexin Gong, Misaki Ishiyama, Shinei Kudo, Shunsuke Kamba, Kazuki Sumiyama, Yutaka Saito, Haruo Nishino, Peixi Liu, Jeremy R. Glissen Brown, Nabil M. Mansour, Seth Gross, Mette Kalager, Michael Bretthauer, Douglas K. Rex, Prateek Sharma, Tyler M. Berzin, Cesare Hassan
GASTROINTESTINAL ENDOSCOPY
(2022)
Meeting Abstract
Gastroenterology & Hepatology
Katsuro Ichimasa, Shinei Kudo, Kenta Nakahara, Masashi Misawa, Shoji Shimada, Yusuke Takehara, Shunpei Mukai, Yuta Kouyama, Yasuharu Maeda, Hideyuki Miyachi, Naruhiko Sawada, Kensaku Mori, Fumio Ishida, Yuichi Mori
GASTROINTESTINAL ENDOSCOPY
(2022)
Meeting Abstract
Gastroenterology & Hepatology
Ishita Barua, Paulina Wieszczy, Shinei Kudo, Masashi Misawa, Oeyvind Holme, Shraddha Gulati, Sophie Williams, Kensaku Mori, Hayato Itoh, Kazumi Takishima, Kenichi Mochizuki, Yuki Miyata, Kentaro Mochida, Yoshika Akimoto, Takanori Kuroki, Yuriko Morita, Osamu Shiina, Shun Kato, Tetsuo Nemoto, Bu Hayee, Mehul Patel, Nishmi Gunasingam, Alexandra J. Kent, Andrew Emmanuel, Carl Munck, Jens Aksel Nilsen, Stine Astrup Hvattum, Svein Oskar Frigstad, Petter Tandberg, Magnus Loberg, Mette Kalager, Amyn Haji, Michael Bretthauer, Yuichi Mori
GASTROINTESTINAL ENDOSCOPY
(2022)
Review
Gastroenterology & Hepatology
Solveig Linnea Veen Larsen, Yuichi Mori
Summary: Artificial intelligence has gained attention in the medical field, particularly in gastroenterology and colonoscopy. The use of novel technologies like deep neural networks allows for real-time computer-aided polyp detection and diagnosis, improving endoscopist performance and reducing unnecessary polypectomy costs. Prospective trials have shown that AI assistance significantly increases polyp and non-advanced adenoma detection, while reducing the adenoma miss rate.