Article
Dermatology
Ronald P. Silverman, John Apostolides, Abhishek Chatterjee, Anthony N. Dardano, Regina M. Fearmonti, Allen Gabriel, Robert T. Grant, Owen N. Johnson, Suresh Koneru, Anna A. Kuang, Andrea A. Moreira, Steven R. Sigalove
Summary: With the increasing use of closed incision negative pressure therapy (ciNPT), new dressing designs have emerged to address implementation challenges. An expert panel has established consensus on the appropriate use of ciNPT with full-coverage dressings, and highlighted the need for further high-quality studies to better understand its benefits.
INTERNATIONAL WOUND JOURNAL
(2022)
Article
Dentistry, Oral Surgery & Medicine
Guillermo Schinini, Diego Sales, Mariel V. Gomez, Hugo J. Romanelli, Leandro Chambrone
Summary: The study found that there were no significant differences in early wound healing outcomes and patient-reported outcomes between sites with sutures and without sutures when a collagen sponge was used in palatal donor areas of SCTG harvested by means of the SIT.
JOURNAL OF PERIODONTOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Tingting Cui, Jiafei Yu, Cai-Feng Wang, Su Chen, Qing Li, Kun Guo, Renkun Qing, Gefei Wang, Jianan Ren
Summary: This work presents a microfluidic assembly technique to fabricate micro-gel ensembles that can precisely tune the pH value of wound surface and accelerate wound healing. By regulating the wound pH, the physiological processes are greatly facilitated, resulting in much accelerated healing of chronic wounds.
Article
Multidisciplinary Sciences
Christiane Fuchs, Linh Pham, Jermaine Henderson, Katherine J. Stalnaker, R. Rox Anderson, Joshua Tam
Summary: MSTC treatment has shown to improve various cellular processes involved in wound healing, including accelerating re-epithelialization, increasing collagen deposition, enhancing dermal remodeling, and attenuating the inflammatory response. This approach can enhance both epidermal and dermal wound healing.
SCIENTIFIC REPORTS
(2021)
Review
Chemistry, Multidisciplinary
Jiayi Mao, Lu Chen, Zhengwei Cai, Shutong Qian, Zhimo Liu, Binfan Zhao, Yuguang Zhang, Xiaoming Sun, Wenguo Cui
Summary: The review discusses the use of macrophage immunotherapy in promoting wound healing, as well as the importance of biomaterials in regulating macrophage signaling for tissue regeneration.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Review
Engineering, Biomedical
Mohammad Hadi Norahan, Sara Cristina Pedroza-Gonz, Monica Gabriela Sanchez-Salazar, Mario Moises Alvarez, Grissel Trujillo de Santiago
Summary: Chronic wounds have become a major problem in healthcare systems, leading to death worldwide. Engineering wound dressings with hydrogels can significantly improve healing time, reduce infections, and lower costs. Hydrogels provide a protective barrier, mimic the extracellular matrix, and create a moist environment. Different fabrication methods and properties of hydrogels have been extensively studied for wound healing applications, including the use of additives to enhance tissue regeneration. Hydrogel engineering offers smart solutions for effective wound healing, with capabilities such as inhibiting bacterial growth, promoting re-epithelialization, and improving tissue functionality.
BIOACTIVE MATERIALS
(2023)
Review
Dermatology
Ge Wang, Fang Yuan, Wanggui Ying, Jie Xu
Summary: A meta-analysis was conducted to assess the effects of different regenerative technologies and materials on wound healing in surgical endodontic therapy. The use of regenerative technologies and materials significantly reduced wound healing failures. Autologous platelet concentrations (APCs) and collagen membrane plus bovine-derived hydroxyapatite were more effective in improving wound healing failure rates than collagen membrane alone.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Biotechnology & Applied Microbiology
Jinli Zhang, Changling Liu, Xiaojian Li, Zhihe Liu, Zhi Zhang
Summary: Hydrogels play a significant role in wound nursing by promoting wound healing and tissue remodeling through reducing inflammation, facilitating vascularization, and supporting cell growth.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Physical
Bin Kong, Rui Liu, Yi Cheng, Xiaodong Cai, Junying Liu, Dagan Zhang, Hui Tan, Yuanjin Zhao
Summary: Developing a biocompatible and multifunctional adhesive hydrogel for wound healing is a highly anticipated clinical application. In this paper, a novel natural biopolymer-derived hydrogel based on aldehyde-modified oxidized guar gum (OGG) and carboxymethyl chitosan (CMCS) is presented. The hydrogel has excellent self-healing ability and shear thinning behavior, and can be injected conveniently through a needle. The physiochemical properties of the hydrogel can be controlled by regulating the concentrations of OGG. In addition, the hydrogel can adhere tightly to tissues and promote wound repair by encapsulating vascular endothelial growth factor (VEGF).
Article
Chemistry, Physical
Bin Kong, Rui Liu, Yi Cheng, Xiaodong Cai, Junying Liu, Dagan Zhang, Hui Tan, Yuanjin Zhao
Summary: This paper presents a biocompatible and multifunctional adhesive hydrogel based on oxidized guar gum and carboxymethyl chitosan for promoting wound healing. The hydrogel has self-healing ability and shear thinning behavior, allowing it to be easily injected. Its physiochemical properties can be controlled by regulating the concentrations of the hydrogel components. Additionally, the hydrogel exhibits strong adhesion to tissues at physiological temperature.
Article
Engineering, Biomedical
Yosuke Asami, Hodaka Sasaki, Atsuro Harada, Kiyotoshi Hanazawa, Takafumi Kobayashi, Gentaro Mori, Yasutomo Yajima
Summary: During wound healing, the gene expression of PIST-specific inflammatory markers was higher in PIST compared to OMT, but there were no significant differences in the expression of standard inflammatory markers. The molecule CXCL2 was locally expressed at the implant-connective tissue interface, with immune cells closely matching its expression pattern. In PIST, seven of the PIST-specific inflammatory markers were specifically and strongly expressed during wound healing and their expression continued until the end of healing, establishing a unique defense mechanism not seen in OMT or PT.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2022)
Article
Dermatology
Xinling Zhang, Xin Yang, Yujie Chen, Guanhuier Wang, Pengbing Ding, Zhenmin Zhao, Hongsen Bi
Summary: Investigated the clinical application value of different flap transfer and repair techniques in adult patients with chronic osteomyelitis, and found that early intervention, thorough debridement, and appropriate wound skin flap coverage are essential for successful wound healing.
INTERNATIONAL WOUND JOURNAL
(2022)
Review
Chemistry, Multidisciplinary
Yongping Liang, Jiahui He, Baolin Guo
Summary: Hydrogels have shown promising advantages as wound dressings due to their excellent biochemical and mechanical properties. This review summarizes the advanced functions of hydrogel dressings, such as antimicrobial, adhesion, hemostasis, anti-inflammatory, substance delivery, self-healing, stimulus response, and conductivity, as well as the emerging wound monitoring feature. The potential applications for different types of wounds, including chronic wounds and focus on infected, burn, and diabetic wounds, are discussed, along with proposed future directions for hydrogel wound dressings in wound healing.
Review
Biotechnology & Applied Microbiology
Hamed Nosrati, Reza Aramideh Khouy, Ali Nosrati, Mohammad Khodaei, Mehdi Banitalebi-Dehkordi, Korosh Ashrafi-Dehkordi, Samira Sanami, Zohreh Alizadeh
Summary: The skin serves as the body's primary barrier against external pathogens and maintaining homeostasis. Damage to the skin can have significant impacts on health and quality of life. Tissue engineering aims to enhance tissue regeneration, with improving angiogenesis being one of the most effective treatments for skin tissue regeneration.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Medicine, General & Internal
Rizwana Imran, Tarek Hassouna, Gurneet Sur, Anna Casey, Victoria Homer, Darren Barton, Kristian Brock, Khaled Altarrah, Naiem Moiemen
Summary: Despite recent advancements in burns wound management, burn wound infection (BWI) remains a major cause of mortality. Acetic acid (AA) has been used as a topical antibacterial agent for burns wounds, but there is no consensus on the optimal concentration, frequency, duration, and tolerability. This study aims to investigate the efficacy and tolerability of 0.5% and 2% AA in colonized burns wounds for 3 days after admission.
