Ruxolitinib for the treatment of patients with steroid-refractory GVHD: an introduction to the REACH  trials

MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation

(2017) N Stickel et al.   LEUKEMIA

Topical Ruxolitinib Protects LGR5+ Stem Cells in the Hair Follicle and Ameliorates Skin Graft-Versus-Host Disease

(2016) Shuichiro Takahashi et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium

(2016) Andrew C. Harris et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Risk Factors for Acute and Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation with Umbilical Cord Blood and Matched Sibling Donors

(2016) Aleksandr Lazaryan et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Analysis of non-relapse mortality and causes of death over 15 years following allogeneic hematopoietic stem cell transplantation

(2016) Y Tanaka et al.   BONE MARROW TRANSPLANTATION

Ruxolitinib treatment for GvHD in patients with myelofibrosis

(2016) Y Mori et al.   BONE MARROW TRANSPLANTATION

Advances in understanding the pathogenesis of graft-versus-host disease

(2016) John Magenau et al.   BRITISH JOURNAL OF HAEMATOLOGY

B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6

(2016) Shaun W. Jackson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ruxolitinib in steroid refractory graft-vs.-host disease: a case report

(2016) Enrico Maffini et al.   Journal of Hematology & Oncology

Measuring Therapeutic Response in Chronic Graft-versus-Host Disease. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2014 Response Criteria Working Group Report

(2015) Stephanie J. Lee et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: I. The 2014 Diagnosis and Staging Working Group Report

(2015) Madan H. Jagasia et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Pharmacologic Inhibition of JAK1/JAK2 Signaling Reduces Experimental Murine Acute GVHD While Preserving GVT Effects

(2015) C. Carniti et al.   CLINICAL CANCER RESEARCH

Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey

(2015) R Zeiser et al.   LEUKEMIA

Type I/II cytokines, JAKs and new strategies for treating autoimmune diseases

(2015) Daniella M. Schwartz et al.   Nature Reviews Rheumatology

Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease

(2014) S. Spoerl et al.   BLOOD

CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease

(2014) Kylie A. Alexander et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacologic Blockade of JAK1/JAK2 Reduces GvHD and Preserves the Graft-Versus-Leukemia Effect

(2014) Jaebok Choi et al.   PLoS One

The JAK-inhibitor ruxolitinib impairs dendritic cell function in vitro and in vivo

(2013) A. Heine et al.   BLOOD

Prophylaxis and treatment of GVHD: EBMT–ELN working group recommendations for a standardized practice

(2013) T Ruutu et al.   BONE MARROW TRANSPLANTATION

Hematopoietic stem cell transplantation: clinical use and perspectives

(2012) Francisco Barriga et al.   BIOLOGICAL RESEARCH

First- and Second-Line Systemic Treatment of Acute Graft-versus-Host Disease: Recommendations of the American Society of Blood and Marrow Transplantation

(2012) Paul J. Martin et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

IFN R signaling mediates alloreactive T-cell trafficking and GVHD

(2012) J. Choi et al.   BLOOD

Diagnosis and management of acute graft-versus-host disease

(2012) Fiona L. Dignan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Diagnosis and management of chronic graft-versus-host disease

(2012) Fiona L. Dignan et al.   BRITISH JOURNAL OF HAEMATOLOGY

Janus kinase-2 inhibition induces durable tolerance to alloantigen by human dendritic cell-stimulated T cells yet preserves immunity to recall antigen

(2011) B. C. Betts et al.   BLOOD

Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria

(2011) M. E. D. Flowers et al.   BLOOD

Risk factors for acute GVHD and survival after hematopoietic cell transplantation

(2011) M. Jagasia et al.   BLOOD

Sequential activation of inflammatory signaling pathways during graft-versus-host disease (GVHD): Early role for STAT1 and STAT3

(2011) Hui-Hui Ma et al.   CELLULAR IMMUNOLOGY

Graft-versus-Host Disease Treatment: Predictors of Survival

(2010) John E. Levine et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

(2010) A. Quintas-Cardama et al.   BLOOD

Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease

(2009) X. Chen et al.   BLOOD

Graft-versus-host disease

(2009) James LM Ferrara et al.   LANCET