Integration of T-cell receptor, Notch and cytokine signals programs mouse γδ T-cell effector differentiation

Role of a selecting ligand in shaping the murine γδ-TCR repertoire

(2018) Shawn P. Fahl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HEB is required for the specification of fetal IL-17-producing γδ T cells

(2017) Tracy S. H. In et al.   Nature Communications

Strong TCRγδ Signaling Prohibits Thymic Development of IL-17A-Secreting γδ T Cells

(2017) Nital Sumaria et al.   Cell Reports

Precocious Interleukin 21 Expression in Naive Mice Identifies a Natural Helper Cell Population in Autoimmune Disease

(2017) Elisabeth A. Marnik et al.   Cell Reports

Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells

(2016) Judith F. Ashouri et al.   JOURNAL OF IMMUNOLOGY

TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets

(2016) Miguel Muñoz-Ruiz et al.   NATURE IMMUNOLOGY

Chronic skin inflammation leads to bone loss by IL-17–mediated inhibition of Wnt signaling in osteoblasts

(2016) Özge Uluçkan et al.   Science Translational Medicine

RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression

(2016) Gerd Meyer zu Horste et al.   Cell Reports

Notch Signaling Contributes to Liver Inflammation by Regulation of Interleukin-22-Producing Cells in Hepatitis B Virus Infection

(2016) Xin Wei et al.   Frontiers in Cellular and Infection Microbiology

The Emerging Roles of Gamma–Delta T Cells in Tissue Inflammation in Experimental Autoimmune Encephalomyelitis

(2016) Sakshi Malik et al.   Frontiers in Immunology

Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner

(2016) Manuel Coutaz et al.   Scientific Reports

The Emerging Protumor Role of    T Lymphocytes: Implications for Cancer Immunotherapy

(2015) M. Rei et al.   CANCER RESEARCH

Gamma delta T-cell differentiation and effector function programming, TCR signal strength, when and how much?

(2015) Payam Zarin et al.   CELLULAR IMMUNOLOGY

IL-17-producing γδT cells are regulated by estrogen during development of experimental arthritis

(2015) Annica Andersson et al.   CLINICAL IMMUNOLOGY

Adaptive Immune-like γ/δ T Lymphocytes Share Many Common Features with Their α/β T Cell Counterparts

(2015) Amélie Lombes et al.   JOURNAL OF IMMUNOLOGY

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

(2015) Seth B. Coffelt et al.   NATURE

Inflammation induces dermal Vγ4+γδT17 memory-like cells that travel to distant skin and accelerate secondary IL-17–driven responses

(2015) Francisco Ramírez-Valle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TCR ligand-inducible expression of CD73 marks γδ lineage commitment and a metastable intermediate in effector specification

(2014) Francis Coffey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Genome-Wide Analysis Identifies a Notch–RBP-Jκ–IL-7Rα Axis That Controls IL-17–Producing γδ T Cell Homeostasis in Mice

(2014) Masataka Nakamura et al.   JOURNAL OF IMMUNOLOGY

Abrogation of Rbpj Attenuates Experimental Autoimmune Uveoretinitis by Inhibiting IL-22-Producing CD4+ T Cells

(2014) Zaied Ahmed Bhuyan et al.   PLoS One

Enforcement of   -lineage commitment by the pre-T-cell receptor in precursors with weak   -TCR signals

(2014) P. Zarin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential developmental requirement and peripheral regulation for dermal Vγ4 and Vγ6T17 cells in health and inflammation

(2014) Yihua Cai et al.   Nature Communications

IL-21 induces IL-22 production in CD4+ T cells

(2014) Ada Yeste et al.   Nature Communications

Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling

(2013) E. Csaszar et al.   BLOOD

Functional development of γδ T cells

(2013) Immo Prinz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of T-cell development by Delta-like 4-expressing fibroblasts

(2013) Mahmood Mohtashami et al.   INTERNATIONAL IMMUNOLOGY

Gammadelta T Cells: Innately Adaptive Immune Cells?

(2013) Leonardo M. R. Ferreira   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Innate-like T cells straddle innate and adaptive immunity by altering antigen-receptor responsiveness

(2013) Melanie Wencker et al.   NATURE IMMUNOLOGY

IL-17-producing γδ T cells and innate lymphoid cells

(2012) Caroline E. Sutton et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The natural and the inducible: interleukin (IL)-17-producing γδ T cells

(2012) Yueh-hsiu Chien et al.   TRENDS IN IMMUNOLOGY

Notch-Hes1 pathway is required for the development of IL-17-producing    T cells

(2011) K. Shibata et al.   BLOOD

Differentiation, phenotype, and function of interleukin-17-producing human V 9V 2 T cells

(2011) N. Caccamo et al.   BLOOD

Skint-1 Identifies a Common Molecular Mechanism for the Development of Interferon-γ-Secreting versus Interleukin-17-Secreting γδ T Cells

(2011) Gleb Turchinovich et al.   IMMUNITY

Caspase-1-Processed Cytokines IL-1  and IL-18 Promote IL-17 Production by    and CD4 T Cells That Mediate Autoimmunity

(2011) S. J. Lalor et al.   JOURNAL OF IMMUNOLOGY

Skint-1 is a highly specific, unique selecting component for epidermal T cells

(2011) S. D. Barbee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid publication: Impairment of macrophage colony-stimulating factor production and lack of resident bone marrow macrophages in the osteopetrotic op/op Mouse

(2010) R. Felix et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cutting Edge: Spontaneous Development of IL-17–Producing γδ T Cells in the Thymus Occurs via a TGF-β1–Dependent Mechanism

(2010) Jeong-su Do et al.   JOURNAL OF IMMUNOLOGY

Direct Comparison of Dll1- and Dll4-Mediated Notch Activation Levels Shows Differential Lymphomyeloid Lineage Commitment Outcomes

(2010) M. Mohtashami et al.   JOURNAL OF IMMUNOLOGY

Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor

(2010) M. S. Alam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CCR6 and NK1.1 distinguish between IL-17A and IFN-γ-producing γδ effector T cells

(2009) Jan D. Haas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Marked Induction of the Helix-Loop-Helix Protein Id3 Promotes the γδ T Cell Fate and Renders Their Functional Maturation Notch Independent

(2009) Jens Peter Holst Lauritsen et al.   IMMUNITY

Spatial Mapping of Thymic Stromal Microenvironments Reveals Unique Features Influencing T Lymphoid Differentiation

(2009) Ann V. Griffith et al.   IMMUNITY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

Regulation of T Cell Activation by Notch Ligand, DLL4, Promotes IL-17 Production and Rorc Activation

(2009) S. Mukherjee et al.   JOURNAL OF IMMUNOLOGY

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY

Thymic Selection Determines γδ T Cell Effector Fate: Antigen-Naive Cells Make Interleukin-17 and Antigen-Experienced Cells Make Interferon γ

(2008) Kirk D.C. Jensen et al.   IMMUNITY

In vivo equilibrium of proinflammatory IL-17+and regulatory IL-10+Foxp3+RORγt+T cells

(2008) Matthias Lochner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Immunological Genome Project: networks of gene expression in immune cells

(2008) Tracy S P Heng et al.   NATURE IMMUNOLOGY