Paeoniflorin ameliorates collagen-induced arthritis via suppressing nuclear factor-κ B signalling pathway in osteoclast differentiation

Immunometabolism in early and late stages of rheumatoid arthritis

(2017) Cornelia M. Weyand et al.   Nature Reviews Rheumatology

Macrophages and skeletal health

(2017) Megan N. Michalski et al.   PHARMACOLOGY & THERAPEUTICS

T Regulatory Cells in Bone Remodelling

(2017) Aline Bozec et al.   Current Osteoporosis Reports

Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation

(2017) Han Zhang et al.   Scientific Reports

Critical Role of LTB4/BLT1 in IL-23–Induced Synovial Inflammation and Osteoclastogenesis via NF-κB

(2016) Laura Bouchareychas et al.   JOURNAL OF IMMUNOLOGY

Unique immunomodulatory effect of paeoniflorin on type I and II macrophages activities

(2016) Tianhang Zhai et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Enhanced osteoclastogenesis by mitochondrial retrograde signaling through transcriptional activation of the cathepsin K gene

(2015) Manti Guha et al.   Annals of the New York Academy of Sciences

Total glucosides of paeony can reduce the hepatotoxicity caused by Methotrexate and Leflunomide combination treatment of active rheumatoid arthritis

(2015) Nan Xiang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Paeoniflorin inhibits skin lesions in imiquimod-induced psoriasis-like mice by downregulating inflammation

(2015) Yue Sun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Total glucosides of peony attenuates experimental autoimmune encephalomyelitis in C57BL/6 mice

(2015) Qiling Huang et al.   JOURNAL OF NEUROIMMUNOLOGY

Paeoniflorin selectively inhibits LPS-provoked B-cell function

(2015) Jie Zhang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Cytokines in rheumatoid arthritis — shaping the immunological landscape

(2015) Iain B. McInnes et al.   Nature Reviews Rheumatology

Novel therapeutic targets in rheumatoid arthritis

(2015) Marije I. Koenders et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Hypericin suppresses osteoclast formation and wear particle-induced osteolysis via modulating ERK signalling pathway

(2014) Zhengxiao Ouyang et al.   BIOCHEMICAL PHARMACOLOGY

Regulation of matrix metalloproteinase-9 protein expression by 1α,25-(OH)2D3during osteoclast differentiation

(2014) Jian-Hong Gu et al.   Journal of Veterinary Science

Total glucosides of paeony inhibits Th1/Th17 cells via decreasing dendritic cells activation in rheumatoid arthritis

(2013) Jinpiao Lin et al.   CELLULAR IMMUNOLOGY

Paeoniflorin inhibits inflammatory responses in mice with allergic contact dermatitis by regulating the balance between inflammatory and anti-inflammatory cytokines

(2013) Chun Wang et al.   INFLAMMATION RESEARCH

Reduced hepatotoxicity by total glucosides of paeony in combination treatment with leflunomide and methotrexate for patients with active rheumatoid arthritis

(2013) Zhu Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Total glucosides of paeony inhibit the proliferation of fibroblast-like synoviocytes through the regulation of G proteins in rats with collagen-induced arthritis

(2013) Xiao-Yi Jia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Paired-box Homeodomain Transcription Factor Pax6 Binds to the Upstream Region of theTRAPGene Promoter and Suppresses Receptor Activator of NF-κB Ligand (RANKL)-induced Osteoclast Differentiation

(2013) Masakazu Kogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Total glucosides of paeony induces regulatory CD4+CD25+ T cells by increasing Foxp3 demethylation in lupus CD4+ T cells

(2012) Ming Zhao et al.   CLINICAL IMMUNOLOGY

Mechanisms involved in the therapeutic effects of Paeonia lactiflora Pallas in rheumatoid arthritis

(2012) Wei Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Regulation of bone by the adaptive immune system in arthritis

(2011) Kazuo Okamoto et al.   ARTHRITIS RESEARCH & THERAPY

Functions of nuclear factor κB in bone

(2010) Brendan F. Boyce et al.   Annals of the New York Academy of Sciences

Interleukin-1 is essential for systemic inflammatory bone loss

(2009) K Polzer et al.   ANNALS OF THE RHEUMATIC DISEASES