Memory control by the B cell antigen receptor

Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?

(2018) Frode L. Jahnsen et al.   TRENDS IN IMMUNOLOGY

Distinct T helper cell dependence of memory B-cell proliferation versus plasma cell differentiation

(2017) Franziska Zabel et al.   IMMUNOLOGY

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

(2017) Nike J. Kräutler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Quantitative in vitro and in vivo models to assess human IgE B cell receptor crosslinking by IgE and EMPD IgE targeting antibodies

(2017) Benjamin Vigl et al.   JOURNAL OF IMMUNOLOGICAL METHODS

IgH isotype-specific B cell receptor expression influences B cell fate

(2017) Pei Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IgG1 memory B cells keep the memory of IgE responses

(2017) Jin-Shu He et al.   Nature Communications

B Cell Intrinsic Mechanisms Constraining IgE Memory

(2017) Brice Laffleur et al.   Frontiers in Immunology

Ontogeny of human IgE-expressing B cells and plasma cells

(2016) F. Ramadani et al.   ALLERGY

Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

(2016) Akshay T. Krishnamurty et al.   IMMUNITY

Fifty years later: Emerging functions of IgE antibodies in host defense, immune regulation, and allergic diseases

(2016) Hans C. Oettgen   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Autonomous membrane IgE signaling prevents IgE-memory formation

(2016) Kei Haniuda et al.   NATURE IMMUNOLOGY

Regulated selection of germinal-center cells into the memory B cell compartment

(2016) Ryo Shinnakasu et al.   NATURE IMMUNOLOGY

Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge

(2016) Pascal Blanc et al.   Nature Communications

Regulation of B cell fate by chronic activity of the IgE B cell receptor

(2016) Zhiyong Yang et al.   eLife

Responsiveness of B cells is regulated by the hinge region of IgD

(2015) Rudolf Übelhart et al.   NATURE IMMUNOLOGY

Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions

(2015) Marc Seifert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acidic phospholipids govern the enhanced activation of IgG-B cell receptor

(2015) Xiangjun Chen et al.   Nature Communications

Reactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production

(2015) Johannes Lutz et al.   Nature Communications

Self-Restrained B Cells Arise following Membrane IgE Expression

(2015) Brice Laffleur et al.   Cell Reports

The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

(2015) Zhengpeng Wan et al.   eLife

Generation of memory B cells inside and outside germinal centers

(2014) Toshitada Takemori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Viral Particles Drive Rapid Differentiation of Memory B Cells into Secondary Plasma Cells Producing Increased Levels of Antibodies

(2014) F. Zabel et al.   JOURNAL OF IMMUNOLOGY

CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype

(2014) Griselda V Zuccarino-Catania et al.   NATURE IMMUNOLOGY

The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module

(2014) Niklas Engels et al.   Nature Communications

A functional BCR in human IgA and IgM plasma cells

(2013) D. Pinto et al.   BLOOD

IgE knock-in mice suggest a role for high levels of IgE in basophil-mediated active systemic anaphylaxis

(2013) Wolger Lübben et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Repression of the Transcription Factor Bach2 Contributes to Predisposition of IgG1 Memory B Cells toward Plasma Cell Differentiation

(2013) Kohei Kometani et al.   IMMUNITY

The distinctive germinal center phase of IgE + B lymphocytes limits their contribution to the classical memory response

(2013) Jin-Shu He et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Diversity Among Memory B Cells: Origin, Consequences, and Utility

(2013) D. Tarlinton et al.   SCIENCE

Fluorescent In Vivo Detection Reveals that IgE+ B Cells Are Restrained by an Intrinsic Cell Fate Predisposition

(2012) Zhiyong Yang et al.   IMMUNITY

Deletion of the α immunoglobulin chain membrane-anchoring region reduces but does not abolish IgA secretion

(2012) Rada Amin et al.   IMMUNOLOGY

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory

(2012) Tomohiro Kaji et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A germinal center–independent pathway generates unswitched memory B cells early in the primary response

(2012) Justin J. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B Cell Receptor-ERK1/2 Signal Cancels PAX5-Dependent Repression of BLIMP1 through PAX5 Phosphorylation: A Mechanism of Antigen-Triggering Plasma Cell Differentiation

(2012) T. Yasuda et al.   JOURNAL OF IMMUNOLOGY

IgE+ memory B cells and plasma cells generated through a germinal-center pathway

(2012) Oezcan Talay et al.   NATURE IMMUNOLOGY

The signaling tool box for tyrosine-based costimulation of lymphocytes

(2011) Niklas Engels et al.   CURRENT OPINION IN IMMUNOLOGY

Grb2 regulates B-cell maturation, B-cell memory responses and inhibits B-cell Ca2+signalling

(2011) Jochen A Ackermann et al.   EMBO JOURNAL

The IgE gene in primates exhibits extraordinary evolutionary diversity

(2011) Pheidias C. Wu et al.   IMMUNOGENETICS

A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

(2011) Tanja A. Schwickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice

(2010) Hans D. Brightbill et al.   JOURNAL OF CLINICAL INVESTIGATION

Antigen affinity discrimination is an intrinsic function of the B cell receptor

(2010) Wanli Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Hierarchy of Maturity of Murine Memory B Cell Subsets

(2010) M. M. Tomayko et al.   JOURNAL OF IMMUNOLOGY

Unique Requirements for Reactivation of Virus-Specific Memory B Lymphocytes

(2010) F. J. Weisel et al.   JOURNAL OF IMMUNOLOGY

Premature replacement of   with   immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation

(2010) S. Duchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Grb2, a simple adapter with complex roles in lymphocyte development, function, and signaling

(2009) Ihn Kyung Jang et al.   IMMUNOLOGICAL REVIEWS

The B-lymphoid Grb2 interaction code

(2009) Konstantin Neumann et al.   IMMUNOLOGICAL REVIEWS

PLC-γ2 is essential for formation and maintenance of memory B cells

(2009) Masaki Hikida et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts

(2009) T. D. Chan et al.   JOURNAL OF IMMUNOLOGY

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

Recruitment of the cytoplasmic adaptor Grb2 to surface IgG and IgE provides antigen receptor–intrinsic costimulation to class-switched B cells

(2009) Niklas Engels et al.   NATURE IMMUNOLOGY

Alleles and isoforms of human membrane-bound IgA1

(2008) Alfur Fu-Hsin Hung et al.   MOLECULAR IMMUNOLOGY