Article
Biochemistry & Molecular Biology
Elif Kaval Oguz
Summary: This study investigated the effects of cypermethrin on the gills of Lake Van fish, revealing that cypermethrin caused stress, deterioration of osmoregulation, DNA damage, and histopathological damage in the gills.
CHEMISTRY AND ECOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Zehra Alkan, Ahmet R. Oguz
Summary: Lake Van in Turkey is the largest lake with brackish and soda water, limiting biodiversity. Lake Van fish are anadromous, migrating to spawn in freshwater pouring into the lake. Research shows that the mucus cells in the gills of Lake Van fish undergo significant changes in different aquatic environments, playing a crucial role in their aquatic adaptation.
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2021)
Article
Fisheries
Ayse Yesilbas, Ahmet Regaib Oguz
Summary: Lake Van fish is the only vertebrate species adapted to the extreme characteristics of Lake Van, migrating to freshwater for breeding annually before returning to the lake. Water ion levels decreased in freshwater areas during reproductive migration, while hormone levels varied in different regions, indicating direct and indirect effects on osmoregulation in the fish species.
AQUACULTURE RESEARCH
(2022)
Article
Chemistry, Applied
Ataman Altug Atici, Ahmet Sepil, Fazil Sen
Summary: This study revealed the presence of microplastic pollution in the gastrointestinal tracts of Alburnus tarichi in Lake Van, with an average of 34 microplastic particles per individual. The majority of the ingested particles were fibers, and blue colored material was the most commonly consumed microplastic. Polyethylene and polypropylene were the main polymers identified in the samples.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
(2021)
Article
Environmental Sciences
Elif Kaval Oguz, Kerem Ozdemir, Guler Unal, Ahmet R. Oguz
Summary: A developed ELISA method was used to determine pollution in Lake Van caused by estrogens and estrogen-like chemicals. Polyclonal antibodies against vitellogenin in male fish plasma were successfully obtained and used in the experiment. The method showed good sensitivity, specificity, and stability with a low detection limit.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Elif Kaval Oguz, Burcu Ergoz, Ahmet R. Oguz
Summary: The study found that exposure to sublethal concentrations of TEB resulted in histopathological changes in the gill, liver, and kidney tissues of Van fish.
CHEMISTRY AND ECOLOGY
(2022)
Article
Fisheries
Semra Saygin, Nazmi Polat, Malte Willmes, Levi S. Lewis, James A. Hobbs, Ataman Altug Atici, Mahmut Elp
Summary: Understanding the contributions of different spawning habitats to fish populations is crucial for fisheries management and species conservation. This study analyzed otoliths and isotope ratios to determine the age structure, natal origins, and contributions of different tributaries to the Tarek population in Lake Van, Turkey. The findings highlight the importance of protecting all watersheds to maintain population stability.
FISHERIES RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Elif Kaval Oguz, Zehra Alkan, Ahmet Regaib Oguz, Burcu Ergoz Azizoglu, Elif Orgi
Summary: This study found that esfenvalerate, a pyrethroid insecticide, caused damage to the gills, liver, and kidneys of Lake Van fish. The observed lesions in these organs can be used as bioindicators of esfenvalerate contamination in Lake Van.
CHEMISTRY AND ECOLOGY
(2023)
Article
Anatomy & Morphology
Burak Kaptaner, Guler Unal, Emine Dogan, Handan Aykut
Summary: In this study, the location, histology, and number of Stannius glands associated with the kidneys of teleost fish were investigated for the first time in Lake Van fish. The findings revealed variations in the number of glands and the presence of two types of cells within the gland parenchyma, with type-I cells being predominant and larger than type-II cells. Additionally, type-II cells were characterized by their darkly stained spherical nucleus and lack of cytoplasmic staining with the mentioned stains.
ANATOMIA HISTOLOGIA EMBRYOLOGIA
(2021)
Article
Anatomy & Morphology
Burak Kaptaner, Handan Aykut, Emine Dogan, Muserref Bostanci
Summary: The teleostean immune system shows morphological variability within and between taxa. This study investigated the histology of thymus, kidney, and spleen in Lake Van fish, revealing characteristics such as predominant lymphoid cells in the thymus, presence of mitotic figures in the kidney, and composition of red and white pulp in the spleen.
ANATOMIA HISTOLOGIA EMBRYOLOGIA
(2021)
Article
Agriculture, Multidisciplinary
Veysi Kizmaz
Summary: This study investigated the distribution of fatty acids in pearl mullet fish, highlighting their importance for health. The analysis revealed changes in phospholipids in both male and female individuals. The findings are significant for the fisheries industry, nutritionists, and researchers.
COGENT FOOD & AGRICULTURE
(2022)
Article
Anatomy & Morphology
Elif Orgi, Ahmet Regaib Oguz
Summary: The pineal gland and melatonin play significant roles in regulating the biological clock, adaptation to seasonal changes, glucose balance, nutrition, and locomotor activities. This study examined the anatomical and histological characteristics of the pineal gland in Lake Van fish. It was found that the plasma melatonin level increased during reproductive migration from lake to stream.
ANATOMIA HISTOLOGIA EMBRYOLOGIA
(2022)
Article
Biochemistry & Molecular Biology
Zehra Alkan, Elif Kaval Oguz, Ahmet Regaib Oguz
Summary: In this study, the effects of sublethal exposure to fluvalinate on mucous cells in the gill tissue of Van fish were investigated. It was found that fluvalinate exposure caused an increase in the number and secretion of mucous cells in the gills, which may have detrimental effects on the fish.
CHEMISTRY AND ECOLOGY
(2023)
Review
Agriculture, Dairy & Animal Science
Malgorzata Witeska, Elzbieta Kondera, Bartosz Bojarski
Summary: Hematological analysis is a commonly used method to assess the physiological state of fish, and it includes various parameters related to blood cells and thrombocytes. It is an important tool in evaluating the impact of substances on fish in ecotoxicology and pharmacotoxicology, together with biochemical and histopathological analyses. The advantages of hematological analysis include its simplicity and cost-effectiveness, while the limitations lie in the requirement of experienced personnel. There is a need for more research on the effects of xenobiotics on the cellular structure of fish head kidney hematopoietic tissue, and we recommend conducting research using both hematological and hematopoietic analysis to assess the impact of toxic substances on fish.
Article
Biochemistry & Molecular Biology
Shanmugam Sudhabose, Balakrishnan Sooryakanth, Muthuswami Ruby Rajan
Summary: This study analyzed the acute toxicity (LC50) of MgO nanoparticles and the hematological and histopathological changes in Cirrhinus mrigala. The results showed that the lethal concentration for 50% of MgO nanoparticles was 4.2321 mg/L. Hematological parameters and histopathological abnormalities were observed on the 7th and 14th days of exposure. The study found that MgO nanoparticles caused damage in gills, muscle, and liver tissues, with more significant effects observed at a concentration of 3.6 mg/L compared to 12 mg/L on the 7th and 14th days of exposure.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Fisheries
Ayse Yesilbas, Ahmet Regaib Oguz
Summary: Lake Van fish is the only vertebrate species adapted to the extreme characteristics of Lake Van, migrating to freshwater for breeding annually before returning to the lake. Water ion levels decreased in freshwater areas during reproductive migration, while hormone levels varied in different regions, indicating direct and indirect effects on osmoregulation in the fish species.
AQUACULTURE RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Elif Kaval Oguz, Burcu Ergoz, Ahmet R. Oguz
Summary: The study found that exposure to sublethal concentrations of TEB resulted in histopathological changes in the gill, liver, and kidney tissues of Van fish.
CHEMISTRY AND ECOLOGY
(2022)
Article
Anatomy & Morphology
Elif Orgi, Ahmet Regaib Oguz
Summary: The pineal gland and melatonin play significant roles in regulating the biological clock, adaptation to seasonal changes, glucose balance, nutrition, and locomotor activities. This study examined the anatomical and histological characteristics of the pineal gland in Lake Van fish. It was found that the plasma melatonin level increased during reproductive migration from lake to stream.
ANATOMIA HISTOLOGIA EMBRYOLOGIA
(2022)
Article
Biology
A. Cilingir Yeltekin
Summary: This study investigated the physiological changes in rainbow trout exposed to different bacterial DNA damage. The results showed that bacterial infection led to a decrease in antioxidant enzymes and cholinergic system enzymes in the gill and intestinal tissues, while 8-OHdG levels increased.
Article
Environmental Sciences
Arzu Ucar, Fatma Betul Ozgeris, Veysel Parlak, Asli Cilingir Yeltekin, Hasan Turkez, Gonca Alak, Muhammed Atamanalp
Summary: This study aimed to investigate the neuroprotective effect of ulexite against acetylferrocene-induced neurotoxicity in brain tissues of Oncorhynchus mykiss. The results showed that acetylferrocene caused neurotoxicity and altered the antioxidant system, inflammatory response, and DNA damage in brain tissues. However, ulexite mitigated these adverse effects and exerted neuroprotective effects by activating the Nrf2 signaling pathway.
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
(2022)
Article
Biochemistry & Molecular Biology
Ash Cilingir Yeltekin, Arzu Ucar, Veysel Parlak, Fatma Betul Ozgeris, Hasan Turkez, Nurinisa Esenbuga, Muhammed Atamanalp, Gonca Alak
Summary: This study investigated the neurotoxic damage potential of ferrocene (FcH) in aquaculture and its related mechanism, while evaluating the protective potential of borax (BX). The results showed that FcH caused oxidative damage and borax was able to mitigate its neurotoxicity.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Muhammed Atamanalp, Hasan Turkez, Asli cilingir Yeltekin, Fatma Betuel Ozgeris, Arzu Ucar, Ozge caglar, Veysel Parlak, Sena Oner, Gonca Alak
Summary: The compound acrylamide (AA) is widely used in industries such as paper, dyes, and plastics, but its water solubility suggests it could pose environmental problems. AA has been found to be neurotoxic, immunotoxic, reproductive toxic, and carcinogenic in animals. This study investigated the potential of boron compounds, such as borax (BX), to ameliorate AA-induced toxicities in rainbow trout. The results showed that AA exposure led to oxidative stress and DNA damage in both blood and liver tissues of the fish. However, co-exposure of BX with AA also elicited oxidative stress and cell death. Overall, BX was suggested as a useful and effective natural agent for preventing and treating AA toxicity in fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2022)
Article
Environmental Sciences
Arzu Ucar, Veysel Parlak, Fatma Betul Ozgeris, Asli Cilingir Yeltekin, Mehmet Enes Arslan, Gonca Alak, Hasan Turkez, Esat Mahmut Kocaman, Muhammed Atamanalp
Summary: This study investigated the effects of exposure to magnetic nanoparticles on Oncorhynchus mykiss and found that ulexite can mitigate neurotoxicity and inflammation. The impact on the antioxidant system and DNA damage was also analyzed. The results showed that magnetic nanoparticles induced stress in O. mykiss, while ulexite exhibited a positive regulatory effect on this stress response.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Applied
Gonca Alak, Asli Cilingir Yeltekin, Mine Kokturk, Mehmet Salih Nas, Veysel Parlak, Mehmet Harbi Calimli, Arzu Ucar, Muhammed Atamanalp
Summary: This study explores the interactions between PdCu@f-MWCNT nanoparticles and zebrafish, and assesses their ecotoxicological risk. The chemical and morphological structures of the nanomaterials are analyzed, and their effects on zebrafish are investigated through biochemical analyses and examination of malformation defects. The results show that the nanoparticles have dose-dependent adverse effects on embryonic development, survival rate, and incidence of malformation in zebrafish.
APPLIED ORGANOMETALLIC CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Arzu Ucar, Asli Cilingir Yeltekin, Mine Kokturk, Mehmet Harbi Calimli, Mehmet Salih Nas, Veysel Parlak, Gonca Alak, Muhammed Atamanalp
Summary: This study investigated the developmental toxicity of zebrafish treated with different concentrations of PdCu@GO. It was found that PdCu@GO administration decreased hatchability and survival rate, and caused dose-dependent cardiac malformation. Furthermore, reactive oxygen species (ROS) and apoptosis were also affected by nano-Pd exposure.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Public, Environmental & Occupational Health
Cigdem Oter, Asli Cilingir Yeltekin, Sama Ammer Abbas El-Tekreti
Summary: By studying the biological parameters of brain tissue in Carassius auratus, it was found that high dose lithium exposure caused oxidative stress, DNA damage, and apoptosis. It was also found that lithium exposure led to a decrease in acetylcholinesterase activity. The solid phase extraction method using sawdust loaded with magnetite nanoparticles showed a high removal yield of about 96% for lithium.
TOXICOLOGY AND INDUSTRIAL HEALTH
(2023)
Article
Fisheries
Ahmet R. Oguz, Ahmet Sepil, Zehra Alkan, Burcu Ergoz Azizoglu, Fazil Sen, Elif Kaval Oguz
Summary: The study examined the histological and immunohistochemical changes in the gills of sailfin velifera acclimated to different salinity levels. Results showed that histological alterations in the gill tissue increased with higher salinity, mainly due to cell hyperplasia and an increase in specific cell types. Different types of cells, such as mucus cells and heat shock protein cells, were observed in the gill tissue under different salinity levels, indicating their important role in regulating ion and salt balance.
AQUACULTURE INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Zehra Alkan, Elif Kaval Oguz, Ahmet Regaib Oguz
Summary: In this study, the effects of sublethal exposure to fluvalinate on mucous cells in the gill tissue of Van fish were investigated. It was found that fluvalinate exposure caused an increase in the number and secretion of mucous cells in the gills, which may have detrimental effects on the fish.
CHEMISTRY AND ECOLOGY
(2023)
Article
Toxicology
Hasan Sac, Asli C. Yeltekin
Summary: The study found that exposure to high concentrations of arsenic in the water caused changes in multiple indicators in the brain tissues of fish, indicating that arsenic can induce oxidative stress.
TOXICOLOGY RESEARCH
(2023)
Article
Veterinary Sciences
Asli C. Yeltekin, Ahmet R. Oguz
Summary: Synthetic detergents contribute to environmental pollution and have a particularly significant impact on Van fish. This study found that different concentrations of sodium lauryl sulphate (SLS) affected the antioxidant levels in Van fish hepatocyte cells and caused an increase in malondialdehyde (MDA) and 8-OHdG levels.
MACEDONIAN VETERINARY REVIEW
(2022)
