Review
Cardiac & Cardiovascular Systems
Saed Alnaimat, Mark Doyle, Kousik Krishnan, Robert W. W. Biederman
Summary: Worsening tricuspid regurgitation (TR) after permanent pacemaker (PPM) or implantable cardioverterdefibrillator (ICD) implantation is a clinical challenge. This meta-analysis found that the overall incidence of TR worsening post-device implantation was 24%, and this worsening significantly increased mortality. Larger right atrial area and female patients were identified as risk factors for TR worsening.
Review
Cardiac & Cardiovascular Systems
Davide Margonato, Francesco Ancona, Giacomo Ingallina, Francesco Melillo, Stefano Stella, Federico Biondi, Antonio Boccellino, Cosmo Godino, Alberto Margonato, Eustachio Agricola
Summary: Tricuspid regurgitation (TR), historically not considered a primary healthcare problem, has recently gained attention from the scientific community. TR can complicate heart failure, most commonly as a functional disease, and its independent prognostic role is still debated. The relationship between TR and LVSD, as well as the potential therapeutic target of TR, remains unclear.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Filippos-Paschalis Rorris, Christos Charitos
Summary: There is conflicting data on the use of implantable cardioverter-defibrillators (ICD) in left ventricular assist device (LVAD) patients. Major guidelines disagree on routine implantation of permanent defibrillators in LVAD recipients, with alternative strategies such as subcutaneous ICDs having disappointing eligibility rates. Wearable cardioverter defibrillators may serve as a bridge to decision for the implantation of a permanent defibrillator in LVAD recipients.
HEART FAILURE REVIEWS
(2021)
Article
Cardiac & Cardiovascular Systems
Xuerong Sun, Bin Zhou, Keping Chen, Wei Hua, Yangang Su, Wei Xu, Fang Wang, Xiaohan Fan, Hongxia Niu, Yan Dai, Zhimin Liu, Shuang Zhao, Shu Zhang
Summary: The study found apparent non-linear associations between night-time heart rate and ventricular tachyarrhythmias (VTAs) and ICD shocks. An increasing incidence of VTAs and ICD shocks was observed at both low and high levels of night-time heart rate, with a night-time heart rate of 50-70 bpm potentially being the optimal therapeutic target for the management of ICD/CRT-D recipients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Daniel J. Friedman, Li Qin, James Freeman, Jagmeet P. Singh, Jeptha P. Curtis, Jonathan P. Piccini, Sana M. Al-Khatib, Kevin P. Jackson
Summary: This study aimed to analyze the rates, reasons, and independent factors associated with left ventricular lead implant failure. The results showed that 3.6% of patients undergoing planned CRT procedures experienced LV lead implant failure. The main reasons for implant failure included venous access issues, coronary sinus access issues, tributary vein access issues, coronary sinus dissection, unacceptable threshold, and diaphragmatic stimulation.
Article
Cardiac & Cardiovascular Systems
Jonas Pausch, Julian Mersmann, Oliver D. Bhadra, Markus J. Barten, Tobias Toennis, Yalin Yildirim, Simon Pecha, Hermann Reichenspurner, Alexander M. Bernhardt
Summary: The prognostic impact of ICD therapy in LVAD recipients remains controversial. ICD therapy in LVAD recipients was not associated with a survival benefit or reduced morbidity after LVAD implantation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Zhengqin Zhai, Shuang Zhao, Xiaoyao Li, Keping Chen, Wei Xu, Wei Hua, Yangang Su, Min Tang, Zeyi Li, Shu Zhang
Summary: The interaction of electrical storm (ES) and impaired left ventricular ejection fraction (LVEF) significantly amplifies the deleterious effects of each other in patients with implantable cardioverter defibrillator (ICD).
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Shengwen Yang, Junhan Zhao, Xi Liu, Jing Wang, Min Gu, Chi Cai, Hongxia Niu, Liang Chen, Wei Hua
Summary: Metabolomics analysis identified dysregulated metabolites associated with life-threatening ventricular arrhythmias and potential biomarkers. Implantable cardioverter defibrillators reduce sudden cardiac death, but current strategies for patient selection and risk stratification are inefficient.
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
James E. Ip, Udhay Krishnan, Leonard N. Girardi, Bruce B. Lerman
Summary: In order to reduce lead-related complications, the development of pacing and defibrillator systems that do not involve hardware traversing the tricuspid annulus is desirable. In some cases where transvenous leads cannot be used, alternative strategies are needed, such as a hybrid system involving endocardial and epicardial components for implanting a biventricular implantable cardioverter defibrillator.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Fabian Barbieri, Isabel Mattig, Niklas Beyhoff, Tharusan Thevathasan, Elena Romero Dorta, Carsten Skurk, Karl Stangl, Ulf Landmesser, Mario Kasner, Henryk Dreger, Markus Reinthaler
Summary: This observational cohort study suggests that transcatheter annuloplasty with the Cardioband(R) device can effectively reduce tricuspid regurgitation in both VFTR and AFTR patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Tanyanan Tanawuttiwat, Mithilesh K. Das, John M. Miller, Maya E. Guglin
Summary: The design of an innovative left ventricular assist device (LVAD) utilizes magnetic levitation technology to suspend the device's rotors, reducing friction and damage to blood or plasma. However, this magnetic field can cause electromagnetic interference (EMI) with other cardiac implantable electronic devices (CIEDs), particularly implantable cardioverter-defibrillators (ICDs). EMI-induced interactions have been reported, leading to inappropriate shocks, connection issues, premature battery depletion, undersensing, and other malfunctions. This article addresses the impact of LVAD-induced EMI on CIED functionality and provides management options for different types of CIEDs.
Review
Cardiac & Cardiovascular Systems
Johanna B. Tonko, Christopher A. Rinaldi
Summary: Implantable cardioverter-defibrillators (ICDs) have revolutionized the treatment of cardiac diseases. However, there is a need for alternative ICD configurations due to expanding patient groups and increasing complications associated with traditional devices.
Article
Cardiac & Cardiovascular Systems
Wolfram Grimm, Kathrin Grimm, Brandon Greene, Mariana Parahuleva
Summary: The study showed that pacing-dependency in patients with CIEDs is significantly associated with factors such as second or third-degree AV block, atrial fibrillation at implant, low LVEF, elevated BNP, chronic kidney disease, and follow-up duration after implantation exceeding 5 years. Other clinical variables like age, gender, diabetes mellitus, underlying heart disease, prior cardiac surgery, and medication during follow-up did not predict pacing-dependency.
CARDIOLOGY JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Hiroto Utsunomiya, Kanako Izumi, Akane Tsuchiya, Atsuo Mogami, Kosuke Takahari, Hajime Takemoto, Erasta Ramandika, Yusuke Ueda, Kiho Itakura, Yukiko Nakano
Summary: This study proposed a novel risk stratification system for severe tricuspid regurgitation and validated its prognostic significance. The findings showed that a large 3D-AROA and reduced right ventricular contractile reserve during exercise were independently associated with poor prognosis.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Medicine, General & Internal
Alwin B. P. Noordman, Michiel Rienstra, Yuri Blaauw, Bart A. Mulder, Alexander H. Maass
Summary: This study investigates the occurrence of appropriate ICD therapies and inappropriate shocks in secondary prevention ICD recipients with ventricular arrhythmia of unclear cause and underlying heart disease. It found that ventricular arrhythmia of unclear cause was significantly associated with fewer appropriate ICD therapies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Sam R. Orde, Sheng-Ying Chung, Juan N. Pulido, Rakesh M. Suri, John M. Stulak, Jae K. Oh, Sorin Pislaru, Hector M. Michelena, Richard C. Daly, Garvan C. Kane
HEART LUNG AND CIRCULATION
(2020)
Article
Cardiac & Cardiovascular Systems
Hongju Zhang, Edward A. El-Am, Jeremy J. Thaden, Sorin V. Pislaru, Christopher G. Scott, Chayakrit Krittanawong, Anwar A. Chahal, Thomas J. Breen, Mackram F. Eleid, Rowlens M. Melduni, Kevin L. Greason, Robert B. McCully, Maurice Enriquez-Sarano, Jae K. Oh, Patricia A. Pellikka, Vuyisile T. Nkomo
Article
Cardiac & Cardiovascular Systems
Parvathi Balachandran, Hartzell Schaff, Brian D. Lahr, Anita Nguyen, Richard C. Daly, Simon Maltais, Sorin Pislaru, Joseph A. Dearani
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2020)
Article
Cardiac & Cardiovascular Systems
Vidhu Anand, Garvan C. Kane, Christopher G. Scott, Sorin Pislaru, Rosalyn O. Adigun, Robert B. McCully, Patricia A. Pellikka, Cristina Pislaru
Summary: This study aimed to evaluate the prognostic significance of peak exercise cardiac power and power reserve in patients with normal left ventricular ejection fraction. The results showed that both peak stress power/mass and power reserve were independently associated with mortality and heart failure at follow-up.
EUROPEAN HEART JOURNAL
(2021)
Editorial Material
Medicine, General & Internal
Jwan A. Naser, John M. Stulak, Ioana Petrescu, Sorin V. Pislaru
MAYO CLINIC PROCEEDINGS
(2022)
Article
Medicine, General & Internal
Nahoko Kato, Mayra Guerrero, Ratnasari Padang, Jennifer M. Amadio, Mackram F. Eleid, Christopher G. Scott, Alexander T. Lee, Sorin Pislaru, Vuyisile T. Nkomo, Patricia A. Pellikka
Summary: This study aimed to evaluate the prevalence and natural history of mitral annulus calcification (MAC) and associated mitral valve dysfunction (MVD) in patients undergoing clinically indicated echocardiography. The results showed that the prevalence of MAC was 23% among the evaluated adult patients, and the prevalence of MVD was more than twice as high in patients with MAC compared to those without MAC. Patients with both MAC and MVD had a higher mortality rate.
MAYO CLINIC PROCEEDINGS
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Sorin Pislaru, Vuyisile T. Nkomo
Editorial Material
Cardiac & Cardiovascular Systems
Sidhartha G. Senapati, Michael S. Sabbah, Sorin Pislaru, Arashk Motiei
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Conor J. Kane, Kyla M. Lara-Breitinger, Mohamad S. Alabdaljabar, Vuyisile T. Nkomo, Ratnasari Padang, Cristina Pislaru, Garvan C. Kane, Christopher Scott, Sorin Pislaru, Grace Lin
Summary: This study aimed to investigate the interaction between pulmonary artery circulation and the right ventricle in patients with tricuspid valve regurgitation (TR) and its association with outcomes. The study found that the pulmonary artery pulsatility index (PAPi) can predict the risk in patients with moderate or severe TR, and low PAPi is associated with right ventricular dysfunction, right heart failure, and worse prognosis.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Letter
Cardiac & Cardiovascular Systems
Jwan A. Naser, Eunjung Lee, Hector I. Michelena, Grace Lin, Patricia A. Pellikka, Vuyisile T. Nkomo, Peter A. Noseworthy, Paul A. Friedman, Zachi I. Attia, Sorin V. Pislaru
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Jwan A. Naser, Eunjung Lee, Christopher G. Scott, Austin M. Kennedy, Patricia A. Pellikka, Grace Lin, Sorin Pislaru, Barry A. Borlaug
Summary: This study aimed to investigate the prevalence and incidence of DD in patients with new-onset AF compared with SR. The results showed that patients with new-onset AF have high-risk features for HFpEF at diagnosis and accelerated progression in DD over time.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Li-Tan Yang, Zi Ye, Muhammad Wajih Ullah, Joseph J. Maleszewski, Christopher G. Scott, Ratnasari Padang, Sorin Pislaru, Vuyisile T. Nkomo, Sunil Mankad, Patricia A. Pellikka, Jae K. Oh, Veronique L. Roger, Maurice Enriquez-Sarano, Hector Michelena
Summary: This study aimed to assess lifetime morbidity and long-term survival in patients with bicuspid aortic valve (BAV) in the community. The results showed that BAV patients have a high lifetime morbidity burden, with a high incidence of complications such as aortic stenosis or regurgitation, aortic surgery, aortic aneurysm, infective endocarditis, and aortic dissection. Compared to patients with typical valvulo-aortopathy, patients with complex valvulo-aortopathy have lower survival rates.
EUROPEAN HEART JOURNAL
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Sorin V. Pislaru
JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
(2023)
Article
Cardiac & Cardiovascular Systems
Jwan A. Naser, Hector Michelena, Grace Lin, Christopher G. Scott, Eunjung Lee, Austin M. Kennedy, Peter A. Noseworthy, Patricia A. Pellikka, Vuyisile T. Nkomo, Sorin Pislaru
Summary: The aim of this study was to investigate the incidence, risk factors, and clinical significance of atrial functional mitral regurgitation (AFMR) in patients with atrial fibrillation (AF) or sinus rhythm (SR). The results showed that the incidence rate of >mild AFMR was 2.6 per 100 person-year in new-onset AF and 0.7 per 100 person-year in SR. Age, sex, left atrial volume index (LAVI), and diastolic dysfunction (DD) were independent risk factors for incident AFMR. AFMR was associated with increased risk of all-cause death.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Jwan A. Naser, Arman Arghami, Mackram F. Eleid, Sorin Pislaru
Summary: This case highlights the importance of recognizing and properly diagnosing bioprosthetic tricuspid valve stenosis in patients with prosthetic valve replacements. Despite the patient having undergone echocardiography, the severity of stenosis was initially underestimated, emphasizing the need for a comprehensive evaluation in patients with a history of valve replacement.
EUROPEAN HEART JOURNAL-CASE REPORTS
(2021)