Article
Cardiac & Cardiovascular Systems
Pietro Palmisano, Domenico Facchin, Matteo Ziacchi, Gerardo Nigro, Antonino Nicosia, Maria Grazia Bongiorni, Luca Tomasi, Andrea Rossi, Paolo De Filippo, Giuseppe Sgarito, Roberto Verlato, Michele Di Silvestro, Saverio Iacopino
Summary: This study compared the rate and nature of device-related complications in patients undergoing leadless intracardiac-permanent pacemaker (L-PM) or conventional transvenous-permanent pacemaker (T-PM) implantation. The results showed that the risk of device-related complications was generally lower in the L-PM group compared to the T-PM group, with significantly lower risk of late complications in the L-PM group.
Article
Cardiac & Cardiovascular Systems
Alexandre Bodin, Nicolas Clementy, Arnaud Bisson, Bertrand Pierre, Julien Herbert, Dominique Babuty, Laurent Fauchier
Summary: Patients treated with leadless ventricular permanent pacemakers had better clinical outcomes within the first month compared to those treated with conventional VVI pacemakers. However, during a midterm follow-up, the risk of all-cause death, cardiovascular death, and endocarditis in patients with leadless VVI pacemakers was not statistically different after propensity score matching.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
George H. Crossley, Jonathan P. Piccini, Colleen Longacre, Lucas Higuera, Kurt Stromberg, Mikhael F. El-Chami
Summary: The Micra CED Study compared the outcomes of Micra pacemakers and transvenous VVI pacemakers using administrative claims data. It found that after 3 years of follow-up, patients with Micra had lower rates of complications, reinterventions, heart failure hospitalizations, and infections compared to patients with transvenous VVI.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2023)
Review
Medicine, General & Internal
Mahesh Gangannapalle, Obinna Monday, Anurag Rawat, Ugonna A. Nwoko, Arun Kumar Mandal, Maham Babur, Tayyaba J. Khan, Sujith K. Palleti
Summary: This meta-analysis compares the safety of leadless pacemakers to transvenous pacemakers. The findings indicate that patients with leadless pacemakers have a lower risk of total complications, device-related complications, pneumothorax, and endocarditis. The risk of reintervention is significantly lower in the leadless pacemaker group. However, the risk of pericardial effusion is significantly higher in the leadless pacemaker group compared to transvenous pacemakers.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Mikhael F. El-Chami, Lindsay Bockstedt, Colleen Longacre, Lucas Higuera, Kurt Stromberg, George Crossley, Robert C. Kowal, Jonathan P. Piccini
Summary: The Micra leadless VVI pacemaker showed lower rates of reinterventions and chronic complications compared to transvenous VVI pacing in a real-world study of US Medicare patients, with no difference in all-cause mortality at 2 years.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Mikhael F. El-Chami, Anand D. Shah
Summary: Leadless pacemakers (LPs) have been used in clinical practice since 2016, with the Micra LP receiving FDA approval. Over 150,000 Micra LPs have been implanted worldwide. In April 2022, the Aveir LP was also approved by the FDA. The implantation of LPs requires a specific set of skills different from traditional pacemakers, and this article focuses on detailing the steps and mitigating major complications.
Article
Cardiac & Cardiovascular Systems
Daniel J. Cantillon, Alok Gambhir, Rajesh Banker, Mayer Rashtian, Rahul Doshi, Nima Badie, Daniel Booth, Weiqun Yang, Peter Nee, Matthew Fishler, David Ligon, Petr Neuzil, Reinoud E. Knops
Summary: This preclinical study demonstrates the chronic performance of implant-to-implant communication that achieves synchronous, dual-chamber pacing with 2 leadless pacemakers, achieving a success rate of 99.2%.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Jonathan P. Piccini, Mikhael El-Chami, Kael Wherry, George H. Crossley, Robert C. Kowal, Kurt Stromberg, Colleen Longacre, Jennifer Hinnenthal, Lindsay Bockstedt
Summary: This study compared patient characteristics and complications between patients implanted with leadless VVI and transvenous VVI pacemakers. Despite significant differences in patient characteristics, patients with leadless VVI pacemakers had higher rates of pericardial effusion and/or perforation but lower rates of other device-related complications and revisions at 6 months.
Article
Cardiac & Cardiovascular Systems
Karel T. N. Breeman, Erik F. J. Oosterwerff, Michiel A. de Graaf, Albert Juffer, Shmaila Saleem-Talib, Alexander H. Maass, Arthur A. M. Wilde, Lucas V. A. Boersma, Hemanth Ramanna, Vincent F. van Dijk, Lieselot van Erven, Peter-Paul H. M. Delnoy, Fleur V. Y. Tjong, Reinoud E. Knops
Summary: This study evaluated the long-term safety and efficacy of leadless pacemakers in a real-world cohort. The results showed a low rate of major complications, with no complications occurring after the acute phase.
Article
Medicine, General & Internal
Michele Bertelli, Sebastiano Toniolo, Matteo Ziacchi, Alessio Gasperetti, Marco Schiavone, Roberto Arosio, Claudio Capobianco, Gianfranco Mitacchione, Giovanni Statuto, Andrea Angeletti, Cristian Martignani, Igor Diemberger, Giovanni Battista Forleo, Mauro Biffi
Summary: The study compared survival and complication rates between leadless and transvenous VVIR pacemakers, finding no significant difference in overall acute and long-term complication rates but higher mortality in the transvenous group due to older patient selection.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Engineering, Electrical & Electronic
Reza Noormohammadi, Ali Khaleghi, Jacob Bergsland, Ilangko Balasingham
Summary: Dual-chamber and multichamber leadless pacemakers (PMs) are emerging solutions for reducing the limitations of conventional wire-based PMs. This article proposes a one-way backscatter communication based on conductive coupling for leadless PMs, enabling communication between the implant capsules and an on-body device without an active transmitter.
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES
(2022)
Article
Cardiac & Cardiovascular Systems
Serge Boveda, Lucas Higuera, Colleen Longacre, Claudia Wolff, Kael Wherry, Kurt Stromberg, Mikhael F. El-Chami
Summary: This study compares the clinical outcomes between leadless pacemakers and transvenous ventricular pacemakers in subgroups of patients at higher risk of pacemaker complications. The results show that leadless pacemakers have lower rates of complications and reinterventions in several high-risk subgroups compared to transvenous ventricular pacemakers.
Review
Cardiac & Cardiovascular Systems
Jurgen Shtembari, Dhan Bahadur Shrestha, Shila Awal, Anuradha Raut, Pratik Gyawali, Temidayo Abe, Nimesh K. Patel, Abhishek Deshmukh, Dinesh Voruganti, Prashant Dattatraya Bhave, Patrick Whalen, Naga Venkata K. Pothineni, Ghanshyam Shantha
Summary: This meta-analysis found that leadless pacemakers were significantly safer than transvenous pacemakers in terms of re-intervention, device dislodgment, pneumothorax, and overall complications. However, there were higher rates of pericardial effusion in the leadless pacemaker group. Due to the limited number of patients included in the studies and the observational nature of all studies, randomized trials are needed to validate these findings.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Reynaldo Sanchez, Anish Nadkarni, Benjamin Buck, Georges Daoud, Tanner Koppert, Toshimasa Okabe, Mahmoud Houmsse, Raul Weiss, Ralph Augostini, John D. Hummel, Steven Kalbfleisch, Emile G. Daoud, Muhammad R. Afzal
Summary: This study demonstrates that the incidence of pacing-induced cardiomyopathy is significantly lower in patients with leadless pacemakers compared to those with transvenous pacemakers. Age and the use of transvenous pacemakers as pacing modality were identified as predictors for pacing-induced cardiomyopathy.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Article
Medicine, General & Internal
Reinoud E. Knops, Vivek Y. Reddy, James E. Ip, Rahul Doshi, Derek V. Exner, Pascal Defaye, Robert Canby, Maria Grazia Bongiorni, Morio Shoda, Gerhard Hindricks, Petr Neuzil, Mayer Rashtian, Karel T. N. Breeman, Jordan R. Nevo, Leonard Ganz, Chris Hubbard, Daniel J. Cantillon
Summary: The study evaluated the safety and performance of a dual-chamber leadless pacemaker system, which demonstrated the ability to provide atrial pacing and reliable atrioventricular synchrony for 3 months after implantation. This technology is of significant importance for the broad application of dual-chamber pacing therapy.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Bharath Yarlagadda, Thomas Deneke, Mohit Turagam, Tawseef Dar, Swathi Paleti, Valay Parikh, Luigi DiBiase, Philipp Halfbass, Pasquale Santangeli, Srijoy Mahapatra, Jie Cheng, Andrea Russo, James Edgerton, Moussa Mansour, Jeremy Ruskin, Srinivas Dukkipati, David Wilber, Vivek Reddy, Douglas Packer, Andrea Natale, Dhanunjaya Lakkireddy
Article
Cardiac & Cardiovascular Systems
Marc A. Miller, Jalaj Garg, Benjamin Salter, Thomas F. Brouwer, Alex J. Mittnacht, Morgan L. Montgomery, Rafael Honikman, Derya E. Arkonac, Subbarao Choudry, Srinivas R. Dukkipati, Vivek Y. Reddy, Menachem M. Weiner
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
William G. Stevenson, Usha B. Tedrow, Vivek Reddy, Amir AbdelWahab, Srinivas Dukkipati, Roy M. John, Akira Fujii, Benjamin Schaeffer, Shinichi Tanigawa, Ihab Elsokkari, Jacob Koruth, Tomofumi Nakamura, Aditi Naniwadekar, Daniele Ghidoli, Christine Pellegrini, John L. Sapp
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Vivek Y. Reddy, Petr Neuzil, Tom de Potter, Jan van der Heyden, Selma C. Tromp, Benno Rensing, Eva Jiresova, Libor Dujka, Veronika Lekesova
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Review
Medicine, General & Internal
David R. Holmes, Mohamad Alkhouli, Vivek Reddy
MAYO CLINIC PROCEEDINGS
(2019)
Review
Cardiac & Cardiovascular Systems
Bhupesh Pathik, Srinivas Dukkipati, Geroge Syros, Vivek Y. Reddy, Jacob Koruth
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2019)
Review
Cardiac & Cardiovascular Systems
Nabeela Karim, Siew Yen Ho, Edward Nicol, Wei Li, Filip Zemrak, Vias Markides, Vivek Reddy, Tom Wong
Article
Cardiac & Cardiovascular Systems
Jin Iwasawa, Jacob S. Koruth, Alexander J. Mittnacht, Van N. Tran, Chandrasekar Palaniswamy, Dinesh Sharma, Rahul Bhardwaj, Aditi Naniwadekar, Kamal Joshi, Aamir Sofi, Georgios Syros, Subbarao Choudry, Marc A. Miller, Srinivas R. Dukkipati, Vivek Y. Reddy
Article
Cardiac & Cardiovascular Systems
Subbarao Choudry, Moussa Mansour, Sri Sundaram, Duy T Nguyen, Srinivas R. Dukkipati, William Whang, Paul Kessman, Vivek Y. Reddy
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Vivek Y. Reddy, Richard Schilling, Massimo Grimaldi, Rodney Horton, Andrea Natale, Stefania Riva, Claudio Tondo, Karl-Heinz Kuck, Petr Neuzil, Kendra McInnis, Moe Bishara, Baohui Zhang, Assaf Govari, Ahmed Abdelaal, Moussa Mansour
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2019)
Letter
Cardiac & Cardiovascular Systems
Vivek Y. Reddy
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
David R. Holmes, Vivek Y. Reddy, Nicole T. Gordon, David Delurgio, Shephal K. Doshi, Amish J. Desai, James E. Stone, Saibal Kar
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2019)
Article
Oncology
Ana Gonzalez-Suarez, Andre d'Avila, Juan J. Perez, Vivek Y. Reddy, Oscar Camara, Enrique Berjano
INTERNATIONAL JOURNAL OF HYPERTHERMIA
(2019)
Article
Cardiac & Cardiovascular Systems
Vivek Y. Reddy, Massimo Grimaldi, Tom De Potter, Johan M. Vijgen, Alan Bulava, Mattias Francis Duytschaever, Martin Martinek, Andrea Natale, Sebastien Knecht, Petr Neuzil, Helmut Puererfellner
JACC-CLINICAL ELECTROPHYSIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Andrea Natale, Sanghamitra Mohanty, P. Y. Liu, Suneet Mittal, Amin Al-Ahmad, David B. De Lurgio, Rodney Horton, William Spear, Shane Bailey, Jared Bunch, Dan Musat, Padraig O'Neill, Steven Compton, Mintu P. Turakhia
JACC-CLINICAL ELECTROPHYSIOLOGY
(2020)