Journal
HEADACHE
Volume 58, Issue 6, Pages 873-882Publisher
WILEY
DOI: 10.1111/head.13311
Keywords
posttraumatic headache; traumatic brain injury; International Classification of Headache Disorders; secondary headache disorders
Categories
Funding
- Wadsworth Term Professorship in Headache Research and Practice at the University of Washington
- National Institute for Disability, Independent Living and Rehabilitation Research
- Amgen
- Allergan
- Impel Biosciences
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There are currently no accepted therapies for posttraumatic headache (PTH). In order to meet the urgent need for effective therapies for PTH, we must continue to address fundamental gaps in our understanding of the clinical course and impact of PTH. Here we examine the existing schema used to characterize the clinical characteristics of PTH, including the International Classification of Headache Disorders (ICHD). There remain unresolved questions about whether to classify patients based on the extent of brain injury or on clinical symptom profiles. There also remain problematic issues of definition such as continuous headache, and chronic daily headache with features of embedded migraine-type within these headaches, which will need to be studied further. We make the case that a symptom-based classification is needed to begin an examination of these unresolved questions, and to establish clinically relevant endpoints for research and clinical trials for effective therapies.
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