Laboratory testing for factor VIII and IX inhibitors in haemophilia: A review

Effects of pre-analytical heat treatment in factor VIII (FVIII) inhibitor assays on FVIII antibody levels

(2018) B. Boylan et al.   HAEMOPHILIA

Limit of detection and threshold for positivity of the Centers for Disease Control and Prevention assay for factor VIII inhibitors

(2017) C. H. Miller et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The use of enhanced half-life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO

(2016) P. Collins et al.   HAEMOPHILIA

Lupus anticoagulants associated inhibitor against factor IX in a young patient with haemophilia B

(2016) A. Barnbrock et al.   HAEMOPHILIA

Quality laboratory issues in bleeding disorders

(2016) D. M. Adcock et al.   HAEMOPHILIA

A variation of the Nijmegen-Bethesda assay using heat or a novel heat/cold pretreatment for the detection of FIX inhibitors in the presence of residual FIX activity

(2016) A. H. Millner et al.   International Journal of Laboratory Hematology

A computer-based model to assess costs associated with the use of factor VIII and factor IX one-stage and chromogenic activity assays

(2016) S. Kitchen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Survey of the anti-factor IX immunoglobulin profiles in patients with hemophilia B using a fluorescence-based immunoassay

(2016) B. Boylan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A critical appraisal of one-stage and chromogenic assays of factor VIII activity

(2016) F. Peyvandi et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Factor VIII–Mimetic Function of Humanized Bispecific Antibody in Hemophilia A

(2016) Midori Shima et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of inhibitors on hemophilia a mortality in the United States

(2015) Christopher E. Walsh et al.   AMERICAN JOURNAL OF HEMATOLOGY

A longitudinal evaluation of anti-FVIII antibodies demonstrated IgG4 subclass is mainly correlated with high-titre inhibitor in haemophilia A patients

(2015) S. A. L. Montalvão et al.   HAEMOPHILIA

The EPIC study: a lesson to learn

(2015) G. Auerswald et al.   HAEMOPHILIA

Longer-acting clotting factor concentrates for hemophilia

(2015) J. S. Powell   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Heat treatment of samples improve the performance of the Nijmegen–Bethesda assay in hemophilia A patients undergoing immune tolerance induction

(2015) Silmara Aparecida de Lima Montalvão et al.   THROMBOSIS RESEARCH

A Public Health Approach to the Prevention of Inhibitors in Hemophilia

(2014) J. Michael Soucie et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Affinity of FVIII-specific antibodies reveals major differences between neutralizing and nonneutralizing antibodies in humans

(2014) C. J. Hofbauer et al.   BLOOD

Toward optimal therapy for inhibitors in hemophilia

(2014) C. L. Kempton et al.   BLOOD

Pre-analytical heat treatment and a FVIII ELISA improve Factor VIII antibody detection in acquired haemophilia A

(2014) Paul Batty et al.   BRITISH JOURNAL OF HAEMATOLOGY

Laboratory testing for factor inhibitors

(2014) E. J. Favaloro et al.   HAEMOPHILIA

Native plasma-derived FVIII/VWF complex has lower sensitivity to FVIII inhibitors than the combination of isolated FVIII and VWF proteins. Impact on Bethesda assay titration of FVIII inhibitors

(2014) M. I. Bravo et al.   HAEMOPHILIA

Does the presence of von Willebrand factor in FVIII-deficient plasma influences the measurement of FVIII inhibitor titres in haemophilia A patients?

(2014) C. Pouplard et al.   International Journal of Laboratory Hematology

Characterization of the anti-factor VIII immunoglobulin profile in patients with hemophilia A by use of a fluorescence-based immunoassay

(2014) B. Boylan et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Definitions in hemophilia: communication from the SSC of the ISTH

(2014) V. S. Blanchette et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Laboratory Diagnosis of Acquired Hemophilia A: Limitations, Consequences, and Challenges

(2014) Sonja Werwitzke et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Comparison of clot-based, chromogenic and fluorescence assays for measurement of factor VIII inhibitors in the US Hemophilia Inhibitor Research Study

(2013) C. H. Miller et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Phenotypes of Allo- and Autoimmune Antibody Responses to FVIII Characterized by Surface Plasmon Resonance

(2013) Kenneth B. Lewis et al.   PLoS One

FEIBA versus NovoSeven in Hemophilia Patients with Inhibitors

(2013) Antonio Coppola et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Acquired haemophilia A: A 2013 update

(2013) Massimo Franchini et al.   THROMBOSIS AND HAEMOSTASIS

Validation of 4% albumin as a diluent in the Bethesda Assay for FVIII inhibitors

(2013) Geoffrey W. Kershaw et al.   THROMBOSIS RESEARCH

Distinct characteristics of antibody responses against factor VIII in healthy individuals and in different cohorts of hemophilia A patients

(2012) S. F. J. Whelan et al.   BLOOD

Diagnosis and treatment of factor VIII and IX inhibitors in congenital haemophilia: (4th edition)

(2012) Peter W. Collins et al.   BRITISH JOURNAL OF HAEMATOLOGY

How I treat inhibitors in haemophilia

(2012) M. MAKRIS et al.   HAEMOPHILIA

Pharmacokinetics and safety of OBI-1, a recombinant B domain-deleted porcine factor VIII, in subjects with haemophilia A

(2012) C. L. KEMPTON et al.   HAEMOPHILIA

False-positive results in ELISA-based anti FVIII antibody assay may occur with lupus anticoagulant and phospholipid antibodies

(2012) M. SAHUD et al.   HAEMOPHILIA

Validation of Nijmegen-Bethesda assay modifications to allow inhibitor measurement during replacement therapy and facilitate inhibitor surveillance

(2012) C. H. MILLER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Low-titre inhibitors, undetectable by the Nijmegen assay, reduce factor VIII half-life after immune tolerance induction

(2012) M. DARDIKH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Physical Functioning in Boys with Hemophilia in the U.S.

(2011) Paul E. Monahan et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

The factor VIII inhibitor assays can be standardized: results of a workshop

(2011) B. VERBRUGGEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Prevalence and epitope specificity of non-neutralising antibodies in a large cohort of haemophilia A patients without inhibitors

(2011) Hervé Chambost et al.   THROMBOSIS AND HAEMOSTASIS

Laboratory Identification of Factor Inhibitors: The Perspective of a Large Tertiary Hemophilia Center

(2010) Geoffrey Kershaw et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Laboratory Assessment of Factor VIII Inhibitor Titer

(2009) Ellinor I.B. Peerschke et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Quantitation of anti-factor VIII antibodies in human plasma

(2009) J. Krudysz-Amblo et al.   BLOOD

Diagnosis and quantification of factor VIII inhibitors

(2009) B. VERBRUGGEN   HAEMOPHILIA

Inhibitors in factor IX deficiency a report of the ISTH-SSC international FIX inhibitor registry (1997-2006)

(2009) M. CHITLUR et al.   HAEMOPHILIA

Functional roles of the factor VIII B domain

(2009) S. W. PIPE   HAEMOPHILIA

The Prevalence of Bleeding Disorders Among Healthy Pediatric Patients With Abnormal Preprocedural Coagulation Studies

(2009) Peter H. Shaw et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

IgG subclasses of anti-FVIII antibodies during immune tolerance induction in patients with hemophilia A

(2008) Pauline M. W. van Helden et al.   BRITISH JOURNAL OF HAEMATOLOGY

Simultaneous detection and epitope mapping of anti-factor VIII antibodies

(2008) Priscilla Lapalud et al.   THROMBOSIS AND HAEMOSTASIS