Utilization of fluoroform for difluoromethylation in continuous flow: a concise synthesis of α-difluoromethyl-amino acids

Continuous Flow Synthesis of a Key 1,4-Benzoxazinone Intermediate via a Nitration/Hydrogenation/Cyclization Sequence

(2017) David Cantillo et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Visible-Light Photocatalytic Decarboxylation of α,β-Unsaturated Carboxylic Acids: Facile Access to Stereoselective Difluoromethylated Styrenes in Batch and Flow

(2017) Xiao-Jing Wei et al.   ACS Catalysis

Continuous-flow difluoromethylation with chlorodifluoromethane under biphasic conditions

(2017) Bernhard Gutmann et al.   Journal of Flow Chemistry

Liquid phase oxidation chemistry in continuous-flow microreactors

(2016) Hannes P. L. Gemoets et al.   CHEMICAL SOCIETY REVIEWS

Taming hazardous chemistry by continuous flow technology

(2016) M. Movsisyan et al.   CHEMICAL SOCIETY REVIEWS

Siladifluoromethylation and Difluoromethylation onto C(sp3), C(sp2), and C(sp) Centers Using Ruppert–Prakash Reagent and Fluoroform

(2016) Kohsuke Aikawa et al.   ORGANIC LETTERS

Continuous-Flow Technology-A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients

(2015) Bernhard Gutmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

α-Difluoromethylation on sp3 Carbon of Nitriles Using Fluoroform and Ruppert–Prakash Reagent

(2015) Kohsuke Aikawa et al.   ORGANIC LETTERS

Difluoromethylation of Terminal Alkynes by Fluoroform

(2015) Satoshi Okusu et al.   ORGANIC LETTERS

The Use of Gases in Flow Synthesis

(2015) Carl J. Mallia et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Use of fluoroform as a source of difluorocarbene in the synthesis of N -CF 2 H heterocycles and difluoromethoxypyridines

(2014) Charles S. Thomoson et al.   JOURNAL OF FLUORINE CHEMISTRY

Single Operation Stereoselective Synthesis ofAerangisLactones: Combining Continuous Flow Hydrogenation and Biocatalysts in a Chemoenzymatic Sequence

(2013) Michael J. Fink et al.   ChemCatChem

Tube-In-Tube Reactor as a Useful Tool for Homo- and Heterogeneous Olefin Metathesis under Continuous Flow Mode

(2013) Krzysztof Skowerski et al.   ChemSusChem

Use of Fluoroform as a Source of Difluorocarbene in the Synthesis of Difluoromethoxy- and Difluorothiomethoxyarenes

(2013) Charles S. Thomoson et al.   JOURNAL OF ORGANIC CHEMISTRY

Umpolung of Fluoroform by CF Bond Activation: Direct Difluoromethylation of Lithium Enolates

(2012) Toshiaki Iida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trifluoromethylation of α-Haloketones

(2012) Petr Novák et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Taming of Fluoroform: Direct Nucleophilic Trifluoromethylation of Si, B, S, and C Centers

(2012) G. K. S. Prakash et al.   SCIENCE

Direct Cupration of Fluoroform

(2011) Alessandro Zanardi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Teflon AF-2400 mediated gas–liquid contact in continuous flow methoxycarbonylations and in-line FTIR measurement of CO concentration

(2011) Peter Koos et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas–liquid contact at elevated pressure

(2011) Matthew O'Brien et al.   Chemical Science

Synthetic strategies to α-trifluoromethyl and α-difluoromethyl substituted α-amino acids

(2008) René Smits et al.   CHEMICAL SOCIETY REVIEWS