Neural functions of bisecting GlcNAc

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Glyco-redox, a link between oxidative stress and changes of glycans: Lessons from research on glutathione, reactive oxygen and nitrogen species to glycobiology

(2016) Naoyuki Taniguchi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Biological roles of glycans

(2016) Ajit Varki   GLYCOBIOLOGY

Expression ofN-Acetylglucosaminyltransferase III Suppresses α2,3-Sialylation, and Its Distinctive Functions in Cell Migration Are Attributed to α2,6-Sialylation Levels

(2016) Jishun Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Disease-associated glycans on cell surface proteins

(2016) Motoko Takahashi et al.   MOLECULAR ASPECTS OF MEDICINE

Epigenetic regulation of neuralN-glycomics

(2016) Yasuhiko Kizuka et al.   PROTEOMICS

Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins

(2016) Masamichi Nagae et al.   Scientific Reports

Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions

(2015) Y. Kizuka et al.   BIOCHEMICAL JOURNAL

An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease

(2015) Y. Kizuka et al.   EMBO Molecular Medicine

Clec4g (LSECtin) interacts with BACE1 and suppresses Aβ generation

(2015) Yasuhiko Kizuka et al.   FEBS LETTERS

Symbol Nomenclature for Graphical Representations of Glycans

(2015) Ajit Varki et al.   GLYCOBIOLOGY

The Absence of Core Fucose Up-regulates GnT-III and Wnt Target Genes

(2014) Ayako Kurimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

(2014) Robert Vassar et al.   JOURNAL OF NEUROCHEMISTRY

Single App knock-in mouse models of Alzheimer's disease

(2014) Takashi Saito et al.   NATURE NEUROSCIENCE

Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

(2013) Cyril Cheret et al.   EMBO JOURNAL

Animal Models of Alzheimer Disease

(2013) F. M. LaFerla et al.   Cold Spring Harbor Perspectives in Medicine

Trafficking and Proteolytic Processing of APP

(2013) C. Haass et al.   Cold Spring Harbor Perspectives in Medicine

Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons

(2012) Peer-Hendrik Kuhn et al.   EMBO JOURNAL

The Neural Cell Adhesion Molecules L1 and CHL1 Are Cleaved by BACE1 Proteasein Vivo

(2012) Lujia Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural Diversity and Changes in Conformational Equilibria of Biantennary Complex-Type N-Glycans in Water Revealed by Replica-Exchange Molecular Dynamics Simulation

(2011) Suyong Re et al.   BIOPHYSICAL JOURNAL

Dementia: A problem for our age

(2011) Alison Abbott   NATURE

Resolving controversies on the path to Alzheimer's therapeutics

(2011) Dennis J Selkoe   NATURE MEDICINE

Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport

(2011) Kazuaki Ohtsubo et al.   NATURE MEDICINE

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

The Bisecting GlcNAc on N-Glycans Inhibits Growth Factor Signaling and Retards Mammary Tumor Progression

(2010) Y. Song et al.   CANCER RESEARCH

Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: their functions and target proteins

(2009) Motoko Takahashi et al.   CARBOHYDRATE RESEARCH

Protective effect of N-glycan bisecting GlcNAc residues on  -amyloid production in Alzheimer's disease

(2009) K. Akasaka-Manya et al.   GLYCOBIOLOGY

From the γ-Glutamyl Cycle to the Glycan Cycle: A Road with Many Turns and Pleasant Surprises

(2009) Naoyuki Taniguchi   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased bisecting and core-fucosylated N-glycans on mutant human amyloid precursor proteins

(2008) Keiko Akasaka-Manya et al.   GLYCOCONJUGATE JOURNAL

Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice

(2008) A. V. Savonenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA