Article
Biochemistry & Molecular Biology
Xiang Zhao, Yuan Zhang, Tianxiang Gao, Na Song
Summary: This study investigated the regulation pathways and genes involved in the immune response of the yellow drum to infection with lipopolysaccharide (LPS) and polyinosinic-polycytidylic acid (poly (I:C)). The results showed that the yellow drum exhibited a stronger response to poly (I:C) infection, and the key functional genes in immune response pathways were significantly affected. This study provides significant information for further understanding the immune system of the yellow drum.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Qianqian Tian, Wanbo Li, Jiacheng Li, Yao Xiao, Baolan Wu, Zhiyong Wang, Fang Han
Summary: The PRPS1 gene in yellow drum plays a key role in immune response to Vibrio harveyi infection. NaPRPS1 is highly expressed in the head-kidney and brain, and its transcription and translation are activated by V. harveyi infection. NaPRPS1 interacts with MyD88 protein to coordinate immune signaling in response to pathogenic infection in yellow drum.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Xiang Zhao, Zhicheng Sun, Tianxiang Gao, Na Song
Summary: This study aimed to investigate the functional genes and pathways in response to salinity stress in the yellow drum. The results showed that genes under salinity stress in the yellow drum exhibited three expression trends, and key pathways for salinity adaptive regulation were identified.
Article
Fisheries
Xiao Xie, Yunyan Jiang, Rujiang Miao, Jiashuang Huang, Liyao Zhou, Jindong Kong, Fei Yin
Summary: Cryptocaryonosis poses a significant threat to marine aquaculture, with yellow drum being highly resistant to Cryptocaryon irritans infection. Transcriptome analysis of yellow drum gill revealed rapid activation of innate and adaptive immune responses post infection, suggesting potential for future therapy development.
JOURNAL OF FISH DISEASES
(2021)
Article
Fisheries
Peng Tan, Wenliang Zhu, Pian Zhang, Ligai Wang, Ruiyi Chen, Dongdong Xu
Summary: This study found that dietary soybean lecithin inclusion can promote the growth and development of yellow drum larvae and improve their intestinal morphology. By increasing fatty acid beta-oxidation and energy production, soybean lecithin can enhance the energy supply to intestinal cells. Meanwhile, feeding on live prey delays body-color transition and increases fecal adhesion in the larvae.
Article
Fisheries
Shihao Zhou, Oianqian Tian, Wanbo Li, Jiacheng Li, Wenjing Li, Fang Han
Summary: This study reports the role of Cygb in the immune response of teleost fish for the first time. Quantitative RT-PCR analysis showed that Cygb was highly expressed in the liver and intestine of yellow drum and its expression can be upregulated by pathogenic attack. Comparative transcriptome analysis identified differentially expressed genes that may play important regulatory roles to Cygb in fish.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Genetics & Heredity
Qihui Zhu, Zeqian Qin, Ruiyi Chen, Ligai Wang, Peng Tan, Dongdong Xu
Summary: This study investigated the gene expression profiles in the yellow drum using comparative transcriptome analyses. The results showed that artificial gynogenesis or hormonal sex reversal had minimal effects on normal female or male life function. Pathways related to oocyte meiosis, cell cycle, riboflavin metabolism, prolactin signaling, PPAR signaling, cholesterol metabolism, and Jak-STAT signaling were found to play important roles in maintaining the regular proliferation and differentiation of females and males in yellow drum.
FRONTIERS IN GENETICS
(2022)
Article
Biochemistry & Molecular Biology
Jia Peng, Jiacheng Li, Jingjie Liang, Wanbo Li, Yao Yang, Yukai Yang, Sen Zhang, Xiaolin Huang, Fang Han
Summary: A C-type lectin-like receptor cluster of differentiation CD302 (YdCD302) in yellow drum was found to be involved in disease resistance against Vibrio harveyi infection. YdCD302 showed high expression in liver and exhibited agglutination and antibacterial activity against V. harveyi cells. The interaction between YdCD302 and V. harveyi cells activated reactive oxygen species production and induced cell death. Up-regulation of YdCD302 expression in immune organs after V. harveyi infection suggests its involvement in innate immunity. This study provides insights into the genetic basis and functional role of YdCD302 in disease resistance.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Baolan Wu, Qing Song, Wanbo Li, Yangjie Xie, Shuai Luo, Qianqian Tian, Ruixiang Zhao, Tong Liu, Zhiyong Wang, Fang Han
Summary: Galectins, including YdGal-3, play a crucial role in immune responses during pathogenic infections. The study found that YdGal-3 expression increased significantly in liver, spleen, and head kidney after infection with Vibrio harveyi. Additionally, YdGal-3 protein showed agglutinating and antibacterial activity against several gram-negative bacteria, indicating its importance in the innate immunity of Nibea albiflora.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Baolan Wu, Qiaoying Li, Wanbo Li, Shuai Luo, Fang Han, Zhiyong Wang
Summary: Galectins, including NaGal-1, play an important role in the innate immune response against bacterial attack in N. albiflora. They are highly expressed in the swim-bladder and their expression can be upregulated by pathogenic attack. NaGal-1 protein can agglutinate and kill certain gram-negative bacteria. These findings provide a basis for further research on the innate immunity of N. albiflora.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Fisheries
Shuai Luo, Baolan Wu, Qiaoying Li, Wanbo Li, Zhiyong Wang, Qing Song, Fang Han
Summary: In this study, a galectin-9 gene named YdGal-9 was identified from Nibea albiflora and its role in fighting bacterial infections was examined. The gene was found to be expressed in various tissues, with the highest level in the kidney. The YdGal-9 protein showed agglutination activity on red blood cells and had the ability to kill gram-negative bacteria. These findings suggest that YdGal-9 plays a vital role in the immune response against bacterial infections.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Multidisciplinary Sciences
Dongdong Xu, Wanchang Zhang, Ruiyi Chen, Hongbin Song, Lu Tian, Peng Tan, Ligai Wang, Qihui Zhu, Bin Wu, Bao Lou, Jiumeng Min, Juhong Zhou
Summary: The study sequenced a near-complete gynogenetic yellow drum genome, predicted 27,069 protein-coding genes, and built a high-density genetic linkage map, providing significant insights into the genetic architecture of economic traits in the yellow drum.
Article
Horticulture
Xingbo Wu, Amanda M. Hulse-Kemp, Phillip A. Wadl, Zach Smith, Keithanne Mockaitis, Margaret E. Staton, Timothy A. Rinehart, Lisa W. Alexander
Summary: Hydrangea, an important ornamental crop cultivated for over 300 years, has been limited in genetic studies due to lack of genetic resources. However, a recent transcriptomic study and large-scale marker development have greatly expanded the genetic resources available for hydrangea, including high-density genetic linkage maps.
Article
Microbiology
Haidong Li, Lei Lu, Ruiyi Chen, Shanshan Li, Dongdong Xu
Summary: Sexual dimorphism is observed in the growth and intestinal microbiota of yellow drums, with significant differences in diversity and community structure between females and males. However, the main composition and functional pathways of the intestinal microbiota show no significant sex differences. The interactions between sex, growth, and intestinal microbiota in yellow drums are comprehensively examined.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Fisheries
Ying Huang, Baolan Wu, Yao Yang, Wanbo Li, Fang Han
Summary: The antimicrobial peptide NKlysin plays a crucial role in N. albiflora's resistance against V. harveyi infection. This study provides new insights into the critical role of NKlysin in the innate immunity of teleost fishes.
FISH & SHELLFISH IMMUNOLOGY
(2023)