SCAMP4 enhances the senescent cell secretome

Identification of senescent cell surface targetable protein DPP4

(2017) Kyoung Mi Kim et al.   GENES & DEVELOPMENT

SASP regulation by noncoding RNA

(2017) Amaresh C. Panda et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Senescent cells: an emerging target for diseases of ageing

(2017) Bennett G. Childs et al.   NATURE REVIEWS DRUG DISCOVERY

Overexpression of the Cytokine BAFF and Autoimmunity Risk

(2017) Maristella Steri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mesenchymal Stem Cells Secretory Responses: Senescence Messaging Secretome and Immunomodulation Perspective

(2017) Victoria V. Lunyak et al.   Frontiers in Genetics

HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNARMRP

(2016) Ji Heon Noh et al.   GENES & DEVELOPMENT

NF90 coordinately represses the senescence-associated secretory phenotype

(2016) Kumiko Tominaga-Yamanaka et al.   Aging-US

Suberoylanilide Hydroxamic Acid Treatment Reveals Crosstalks among Proteome, Ubiquitylome and Acetylome in Non-Small Cell Lung Cancer A549 Cell Line

(2015) Quan Wu et al.   Scientific Reports

Senescent cells: SASPected drivers of age-related pathologies

(2014) Yossi Ovadya et al.   BIOGERONTOLOGY

An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

(2014) Marco Demaria et al.   DEVELOPMENTAL CELL

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning

(2013) Mekayla Storer et al.   CELL

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The essence of senescence

(2010) T. Kuilman et al.   GENES & DEVELOPMENT

Pathways for Cytokine Secretion

(2010) Amanda C. Stanley et al.   PHYSIOLOGY

Human SCAMP5, a Novel Secretory Carrier Membrane Protein, Facilitates Calcium-Triggered Cytokine Secretion by Interaction with SNARE Machinery

(2009) C. Han et al.   JOURNAL OF IMMUNOLOGY

Cell surface-bound IL-1  is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network

(2009) A. V. Orjalo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular senescence in vivo: a barrier to tumorigenesis

(2008) Alexandre Prieur et al.   CURRENT OPINION IN CELL BIOLOGY

Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

(2008) Darren J. Baker et al.   NATURE CELL BIOLOGY

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY