Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia

(2017) Matthew J. Smith et al.   Nature Communications

PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity

(2016) Bo Zhou et al.   MOLECULAR CELL

The molecular mechanics of mixed lineage leukemia

(2016) R K Slany   ONCOGENE

Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential

(2015) Aravinda Kuntimaddi et al.   Cell Reports

AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes

(2014) Aniruddha J. Deshpande et al.   CANCER CELL

Characterization and inhibition of AF10-mediated interaction

(2014) Sven Hagen et al.   JOURNAL OF PEPTIDE SCIENCE

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Abrogation of MLL–AF10 and CALM–AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l

(2012) L Chen et al.   LEUKEMIA

The Pathogenesis of Mixed-Lineage Leukemia

(2011) Andrew G. Muntean et al.   Annual Review of Pathology-Mechanisms of Disease

HMMER web server: interactive sequence similarity searching

(2011) R. D. Finn et al.   NUCLEIC ACIDS RESEARCH

Mixed lineage leukemia: a structure-function perspective of the MLL1 protein

(2010) Michael S. Cosgrove et al.   FEBS Journal

Cellular zinc homeostasis is a regulator in monocyte differentiation of HL-60 cells by 1α,25-dihydroxyvitamin D3

(2010) Svenja Dubben et al.   JOURNAL OF LEUKOCYTE BIOLOGY

AF17 Competes with AF9 for Binding to Dot1a to Up-regulate Transcription of Epithelial Na+Channel α

(2009) Mary Rose Reisenauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY