Article
Surgery
Yeongkeun Kwon, Jin-Won Kwon, Dohyang Kim, Jane Ha, Shin-Hoo Park, Jinseub Hwang, Yoonseok Heo, Sungsoo Park
Summary: Preoperative clinical parameters predict diabetes remission and relapse, while greater postoperative weight decrease may increase the likelihood of diabetes remission.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2021)
Article
Endocrinology & Metabolism
Ted D. Adams, Huong Meeks, Alison Fraser, Lance E. Davidson, John Holmen, Michael Newman, Anna R. Ibele, Mary Playdon, Sheetal Hardikar, Nathan Richards, Steven C. Hunt, Jaewhan Kim
Summary: This study found that bariatric surgery patients had a 25% lower risk of developing cancer compared to a nonsurgical comparison group. Among female patients, the risk of developing cancer was reduced by 67% and cancer mortality was significantly lower by 53% after surgery.
Article
Oncology
Muzaffer Ece Hakan Sahin, Feray Akbas, Aytul Hande Yardimci, Eren Sahin
Summary: Sarcopenic obesity is associated with the incidence and mortality rate of gastric cancer. Sarcopenia is more prevalent in the elderly population, while a higher body mass index (BMI) is associated with improved survival.
Article
Nutrition & Dietetics
Claudia Martinez-Tapia, Thomas Diot, Nadia Oubaya, Elena Paillaud, Johanne Poisson, Mathilde Gisselbrecht, Laure Morisset, Philippe Caillet, Aurelie Baudin, Frederic Pamoukdjian, Amaury Broussier, Sylvie Bastuji-Garin, Marie Laurent, Florence Canoui-Poitrine
Summary: The study found that only older obese women with cancer who had minimal weight loss before diagnosis had a lower risk of mortality compared to normal-weight counterparts. However, overweight and obese men did not have a lower mortality risk regardless of weight loss.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Gastroenterology & Hepatology
Su Youn Nam, Seong Woo Jeon, Yong Hwan Kwon, Oh-kyung Kwon
Summary: The impact of age, sex, and BMI on mortality in gastric cancer patients varies, with women showing more favorable outcomes in certain aspects compared to men. Results suggest the need for sex-specific approaches in prognostic predictions for gastric cancer patients.
DIGESTIVE AND LIVER DISEASE
(2021)
Article
Surgery
Hideaki Suematsu, Chikara Kunisaki, Hiroshi Miyamato, Kei Sato, Sho Sato, Yusaku Tanaka, Norio Yukawa, Yasushi Rino, Takashi Kosaka, Itaru Endo, Munetaka Masuda
Summary: This study evaluated short- and long-term outcomes in obese patients with gastric cancer undergoing totally laparoscopic total gastrectomy, finding that although the operation time was longer, obesity was not identified as a significant risk factor for postoperative complications and overall survival rate.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Review
Nutrition & Dietetics
Moustapha Drame, Lidvine Godaert
Summary: The obesity paradox refers to the counterintuitive finding that older adults who are overweight or obese may have better outcomes in certain diseases compared to those with normal weight or underweight. This systematic review aims to summarize publications on the obesity paradox in older adults and gain a deeper understanding of this phenomenon.
Review
Endocrinology & Metabolism
Natasha Wiebe, Anita Lloyd, Ellen T. T. Crumley, Marcello Tonelli
Summary: The association between mortality and body mass index (BMI) is affected by fasting insulin and c-reactive protein. Increased fat mass may play a mediating role in the relationship between hyperinsulinemia, hyperinflammation, and mortality. This study aims to investigate the average associations between BMI and mortality risk and explore the impact of adjusting for insulin and markers of inflammation on this association.
Article
Biochemistry & Molecular Biology
Jian Xiao, Kuan Shen, Kanghui Liu, Yuanhang Wang, Hao Fan, Quan Cheng, Xinyi Zhou, Li Hu, Gang Wang, Zekuan Xu, Li Yang
Summary: This study found that high BMI significantly increases the risk of lymph node metastasis (LNM) in gastric cancer (GC) and promotes lipid accumulation in LNM. Increased low-density lipoprotein cholesterol is a risk factor in females. Functional enrichment analysis reveals a connection between lipid metabolism and LNM.
LIPIDS IN HEALTH AND DISEASE
(2022)
Article
Endocrinology & Metabolism
Dag Holmberg, Giola Santoni, Joonas H. Kauppila, Sheraz R. Markar, Jesper Lagergren
Summary: This study compared the long-term survival rates of sleeve gastrectomy and gastric bypass in obese patients and found that the overall survival rate of sleeve gastrectomy is comparable to gastric bypass and may even be better in recent years. Additionally, patients with diabetes had a higher all-cause mortality rate after sleeve gastrectomy compared to gastric bypass.
Article
Gastroenterology & Hepatology
Nabil Tariq, Ashish Saharia, Ugoeze Nwokedi, Mark J. Hobeika, Constance M. Mobley, David Hsu, Lucy M. Potter, Linda W. Moore, Ahmed Elaileh, Vadim Sherman, R. Mark Ghobrial
Summary: This study investigated the feasibility and outcomes of sleeve gastrectomy (SG) during liver transplantation (LT) in patients with high Model for End-Stage Liver Disease (MELD) score. The results showed that simultaneous LT and SG in patients with high MELD score resulted in sustained weight loss and similar graft survival at 1 year.
LIVER TRANSPLANTATION
(2023)
Review
Oncology
Narges Azizi, Moein Zangiabadian, Golnoosh Seifi, Afshan Davari, Elham Yekekhani, Seyed Amir Ahmad Safavi-Naini, Nathan A. Berger, Mohammad Javad Nasiri, Mohammad-Reza Sohrabi
Summary: This systematic review and meta-analysis aimed to investigate the association between gastric cancer risk and abnormal body mass index. The results showed that obesity and overweight increase the risk of gastric cancer, while underweight is not associated. These findings can help in developing preventive strategies for controlling obesity and overweight.
Article
Surgery
Kazuaki Matsui, Shinichi Sakuramoto, Hirofumi Sugita, Keiji Nishibeppu, Gen Ebara, Shohei Fujita, Shiro Fujihata, Shuichiro Oya, Yutaka Miyawaki, Hiroshi Sato, Keishi Yamashita
Summary: This study compared the outcomes of laparoscopic and open distal gastrectomy for gastric cancer in overweight Japanese patients. The results showed that laparoscopic distal gastrectomy was associated with lower incidence of postoperative complications without compromising long-term survival.
Article
Gastroenterology & Hepatology
In Young Choi, Yoon Jin Choi, Dong Wook Shin, Kyung Do Han, Keun Hye Jeon, Su-Min Jeong, Jung Eun Yoo
Summary: This study found a positive association between the highest BMI and WC category and the risk of GC in postmenopausal women, while no such association was evident in premenopausal women.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Endocrinology & Metabolism
Xiaoli Xu, Zehua Weng, Xiufang Yang, Juan Ni, Ming-min Ma, Ying-chun Huang, Xiao-ling Yin
Summary: In this meta-analysis, the association between body mass index (BMI) and sepsis mortality was investigated. The results showed that underweight BMI was associated with increased sepsis mortality, while overweight and obesity were associated with lower mortality in sepsis. Therefore, a personalized approach should be taken in the clinical management of sepsis.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Allergy
Sukyung Kim, Minji Kim, Jiwon Kim, Boram Park, Nuri Min, Minyoung Jung, Seoyoung Yu, Ji Young Lee, Hye Won Yoo, Hye-Young Kim, Kangmo Ahn, Jihyun Kim
Summary: This study evaluated the reliability and validity of the Korean version of the Food Allergy Quality of Life Questionnaire-Parent Form (K-FAQLQ-PF) and identified clinical characteristics related to low quality of life (QoL) in Korean children with food allergy (FA). The K-FAQLQ-PF was found to be a valid and reliable tool to assess psychosocial QoL in Korean children with FAs. Age, sex, residential area, and comorbid atopic dermatitis (AD) were found to affect the QoL of pediatric patients with FA.
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH
(2023)
Article
Oncology
Sang Soo Eom, Sin Hye Park, Bang Wool Eom, Hong Man Yoon, Young-Woo Kim, Keun Won Ryu
Summary: This study aimed to compare the outcomes of laparoscopic total gastrectomy (LTG) with open total gastrectomy (OTG). There was no significant difference in short-term outcomes between the two groups, and the 3-year disease-free survival and 5-year overall survival rates were also similar. Thus, LTG could be an alternative to OTG.
Article
Oncology
Tae-Han Kim, In-Ho Kim, Seung Joo Kang, Miyoung Choi, Baek-Hui Kim, Bang Wool Eom, Bum Jun Kim, Byung-Hoon Min, Chang In Choi, Cheol Min Shin, Chung Hyun Tae, Chung Sik Gong, Dong Jin Kim, Arthur Eung-Hyuck Cho, Eun Jeong Gong, Geum Jong Song, Hyeon-Su Im, Hye Seong Ahn, Hyun Lim, Hyung-Don Kim, Jae-Joon Kim, Jeong Il Yu, Jeong Won Lee, Ji Yeon Park, Jwa Hoon Kim, Kyoung Doo Song, Minkyu Jung, Mi Ran Jung, Sang-Yong Son, Shin-Hoo Park, Soo Jin Kim, Sung Hak Lee, Tae-Yong Kim, Woo Kyun Bae, Woong Sub Koom, Yeseob Jee, Yoo Min Kim, Yoonjin Kwak, Young Suk Park, Hye Sook Han, Su Youn Nam, Seong-Ho Kong
Summary: This is the fourth gastric cancer guideline published in Korea, revised in 2018 based on evidence-based approach. It is a collaborative work of an interdisciplinary working group and includes 33 updated or proposed key questions, with 40 statements developed based on systematic review. The evidence level and recommendations were categorized according to the Grading of Recommendations, Assessment, Development and Evaluation proposition. The guideline covers screening, diagnosis, staging and follow-up.
JOURNAL OF GASTRIC CANCER
(2023)
Article
Oncology
Young Soo Park, Myeong-Cherl Kook, Baek-hui Kim, Hye Seung Lee, Dong-Wook Kang, Mi-Jin Gu, Ok Ran Shin, Younghee Choi, Wonae Lee, Hyunki Kim, In Hye Song, Kyoung-Mee Kim, Hee Sung Kim, Guhyun Kang, Do Youn Park, So -Young Jin, Joon Mee Kim, Yoon Jung Choi, Hee Kyung Chang, Soomin Ahn, Mee Soo Chang, Song-Hee Han, Yoonjin Kwak, An Na Seo, Sung Hak Lee, Mee-Yon Cho
Summary: This edition is composed of standard data elements and conditional data elements. Standard data elements contain basic pathological findings and necessary items to predict the prognosis of GC patients, while conditional data elements include additional diagnostic and prognostic factors relevant to adjuvant therapy, such as molecular biomarkers. They are designed to allow pathologists to selectively choose appropriate items based on their institution's environment. The standardized pathology report aims to improve GC diagnosis and facilitate large-scale research.
JOURNAL OF GASTRIC CANCER
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sang Oh Yun, Kyo Won Lee, Jae Berm Park, Min Jung Kim, Sung Yoon Park, Boram Park
Summary: This study evaluated the role of donor kidney ultrasonography in predicting functional kidney volume and identifying ideal kidney grafts in deceased donor kidney transplantation. The product of renal length and cortical thickness was found to be a significant predictor of graft function. Preoperative ultrasound can be used to evaluate donor kidney function and predict short-term graft survival.
Review
Pathology
Young Soo Park, Myeong-Cherl Kook, Baek-hui Kim, Hye Seung Lee, Dong-Wook Kang, Mi-Jin Gu, Ok Ran Shin, Younghee Choi, Wonae Lee, Hyunki Kim, In Hye Song, Kyoung-Mee Kim, Hee Sung Kim, Guhyun Kang, Do Youn Park, So -Young Jin, Joon Mee Kim, Yoon Jung Choi, Hee Kyung Chang, Soomin Ahn, Mee Soo Chang, Song-Hee Han, Yoonjin Kwak, An Na Seo, Sung Hak Lee, Mee-Yon Cho
Summary: The first edition of 'A Standardized Pathology Report for Gastric Cancer' was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago. This second edition consists of standard data elements and conditional data elements, including basic pathologic findings and items necessary for predicting the prognosis of GC patients. Other factors relevant to adjuvant therapy are classified as conditional data elements. The standardized pathology report will be helpful for GC diagnosis and facilitate collaborative studies.
JOURNAL OF PATHOLOGY AND TRANSLATIONAL MEDICINE
(2023)
Article
Oncology
Drolaiz H. W. Liu, Young-Woo Kim, Nina Sefcovicova, Jon P. Laye, Lindsay C. Hewitt, Andrew F. Irvine, Vincent Vromen, Yannick Janssen, Naser Davarzani, Gregorio E. Fazzi, Shahab Jolani, Veerle Melotte, Derek R. Magee, Myeong-Cherl Kook, Hyunki Kim, Rupert Langer, Jae-Ho Cheong, Heike I. Grabsch
Summary: This study suggests that the quantification of TIL density in routine HE stained tissue sections can be a novel and clinically useful biomarker for identifying stage II-III gastric cancer patients who would benefit from adjuvant chemotherapy. Further validation through prospective studies is needed.
BRITISH JOURNAL OF CANCER
(2023)
Article
Oncology
Bokyung Kim, Kyungdo Han, Hyunsoo Chung, Sang Gyun Kim, Soo-Jeong Cho
Summary: This study found that smoking cessation and alcohol abstinence are associated with reduced risk of developing depression in patients with gastric cancer who undergo surgery, while starting regular physical activity is not associated with risk of depression.
Article
Surgery
Soo Yeong Lim, Hong Man Yoon, Myeong-Cherl Kook, Jin Il Jang, Peter T. C. So, Jeon Woong Kang, Hyung Min Kim
Summary: A machine-learning-based spectro-histological model was developed to accurately differentiate different layers of gastric tissue using autofluorescence spectra. The model achieved high prediction accuracy for mucosa, submucosa, and muscularis propria, with scores of 92.0%, 90.1%, and 91.4% respectively. The model was tested on both sliced and block tissue samples using a fast fluorescence imaging scanner.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Multidisciplinary Sciences
Yoo-Na Kim, Boram Park, Jae Weon Kim, Byoung Gie Kim, Sang Wun Kim, Hee Seung Kim, Chel Hun Choi, Myong Cheol Lim, Natalie Y. L. Ngoi, David S. P. Tan, Jung-Yun Lee
Summary: This multicenter study investigates the efficacy and safety of triplet maintenance therapy in platinum-sensitive recurrent ovarian cancer patients. The results show that the therapy achieved the pre-specified primary endpoint of 6-month progression-free survival, and also demonstrated positive outcomes in terms of median progression-free survival, 12-month progression-free survival, overall survival, and safety.
NATURE COMMUNICATIONS
(2023)
Article
Medicine, General & Internal
Seung Joo Kang, Jae Gyu Kim, Hee Seok Moon, Myeong-Cherl Kook, Jong Yeul Lee, Chang Seok Bang, Chung Hyun Tae, Eun Jeong Gong, Su Youn Nam, Hyun Jung Kim
Summary: Gastritis is a common disease characterized by inflammation of the gastric mucosa, with various classification systems available. Recent emphasis has been placed on H. pylori gastritis due to its association with gastric cancer development and the potential for prevention through eradication. Although Korea has the highest incidence rate of gastric cancer globally, there are currently no clinical guidelines for atrophic gastritis and intestinal metaplasia. To address this, the Korean College of Helicobacter and Upper Gastrointestinal Research developed evidence-based guidelines through systematic review and made recommendations for key questions. This guideline will need periodic revision as new evidence emerges.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Medicine, General & Internal
Bokyung Kim, Jin-Hyung Jung, Kyungdo Han, Seungkyung Kang, Eunwoo Lee, Hyunsoo Chung, Sang Gyun Kim, Soo-Jeong Cho
Summary: This study aimed to investigate the effect of histamine-2 receptor antagonist (H2RA) and proton pump inhibitor (PPI) use on the positivity rate and clinical outcomes of COVID-19. The results showed that H2RA and PPI use was associated with a decreased risk for SARS-CoV-2 infection, but did not affect clinical outcomes. The protective effect of H2RA and PPI was not significant in patients with comorbidities such as diabetes, hypertension, and dyslipidemia.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Correction
Oncology
Tae-Han Kim, In-Ho Kim, Seung Joo Kang, Miyoung Choi, Baek-Hui Kim, Bang Wool Eom, Bum Jun Kim, Byung-Hoon Min, Chang In Choi, Cheol Min Shin, Chung Hyun Tae, Chung Sik Gong, Dong Jin Kim, Arthur Eung-Hyuck Cho, Eun Jeong Gong, Geum Jong Song, Hyeon-Su Im, Hye Seong Ahn, Hyun Lim, Hyung-Don Kim, Jae-Joon Kim, Jeong Il Yu, Jeong Won Lee, Ji Yeon Park, Jwa Hoon Kim, Kyoung Doo Song, Minkyu Jung, Mi Ran Jung, Sang-Yong Son, Shin-Hoo Park, Soo Jin Kim, Sung Hak Lee, Tae-Yong Kim, Woo Kyun Bae, Woong Sub Koom, Yeseob Jee, Yoo Min Kim, Yoonjin Kwak, Young Suk Park, Hye Sook Han, Su Youn Nam, Seong-Ho Kong
JOURNAL OF GASTRIC CANCER
(2023)
Article
Oncology
Sang Soo Eom, Sin Hye Park, Bang Wool Eom, Hong Man Yoon, Young-Woo Kim, Keun Won Ryu
Summary: This study evaluated the compliance with gastric cancer treatment guidelines in real-world clinical practice in Korea and found relatively high compliance rates.
JOURNAL OF GASTRIC CANCER
(2023)
Article
Oncology
Sin Hye Park, Hong Man Yoon, Keun Won Ryu, Young-Woo Kim, Mira Han, Bang Wool Eom
Summary: This study compared the long-term functional and patient-reported outcomes between intra-corporeal delta-shaped gastroduodenostomy and gastrojejunostomy after laparoscopic distal gastrectomy for gastric cancer. The results showed that there were no significant differences in postoperative complications or nutritional parameters between the two groups. However, the delta group had more residual food and worse short-term quality of life regarding insomnia, reflux symptoms, and dry mouth.
JOURNAL OF GASTRIC CANCER
(2023)