Cell entry mechanisms of HSV: what we have learned in recent years

Heparanase is a host enzyme required for herpes simplex virus-1 release from cells

(2015) Satvik R. Hadigal et al.   Nature Communications

Virus and Cell Fusion Mechanisms

(2014) Benjamin Podbilewicz   Annual Review of Cell and Developmental Biology

A Replication Competent HSV-1(McKrae) with a Mutation in the Amino-terminus of Glycoprotein K (gK) is Unable to Infect Mouse Trigeminal Ganglia after Cornea Infection

(2014) Ahmad A. Saied et al.   CURRENT EYE RESEARCH

Substitution of Herpes Simplex Virus 1 Entry Glycoproteins with Those of Saimiriine Herpesvirus 1 Reveals a gD-gH/gL Functional Interaction and a Region within the gD Profusion Domain That Is Critical for Fusion

(2014) Q. Fan et al.   JOURNAL OF VIROLOGY

Comprehensive Analysis of Herpes Simplex Virus 1 (HSV-1) Entry Mediated by Zebrafish 3-O-Sulfotransferase Isoforms: Implications for the Development of a Zebrafish Model of HSV-1 Infection

(2014) A. M. Yakoub et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Type 2 Glycoprotein H Interacts with Integrin  v 3 To Facilitate Viral Entry and Calcium Signaling in Human Genital Tract Epithelial Cells

(2014) N. Cheshenko et al.   JOURNAL OF VIROLOGY

Nonmuscle Myosin Heavy Chain IIB Mediates Herpes Simplex Virus 1 Entry

(2014) Jun Arii et al.   JOURNAL OF VIROLOGY

Characterization of a Proteolytically Stable D-Peptide That Suppresses Herpes Simplex Virus 1 Infection: Implications for the Development of Entry-Based Antiviral Therapy

(2014) Dinesh Jaishankar et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus gE/gI Extracellular Domains Promote Axonal Transport and Spread from Neurons to Epithelial Cells

(2014) P. W. Howard et al.   JOURNAL OF VIROLOGY

A Small Molecule Inhibits Virion Attachment to Heparan Sulfate- or Sialic Acid-Containing Glycans

(2014) Che C. Colpitts et al.   JOURNAL OF VIROLOGY

Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance

(2014) Scott H James et al.   Current Opinion in Virology

Viral exploitation of actin: force-generation and scaffolding functions in viral infection

(2014) Mark Spear et al.   VIROLOGICA SINICA

Type I Interferon and NF- B Activation Elicited by Herpes Simplex Virus gH/gL via  v 3 Integrin in Epithelial and Neuronal Cell Lines

(2013) T. Gianni et al.   JOURNAL OF VIROLOGY

Displacement of the C Terminus of Herpes Simplex Virus gD Is Sufficient To Expose the Fusion-Activating Interfaces on gD

(2013) John R. Gallagher et al.   JOURNAL OF VIROLOGY

Interactions between Herpesvirus Entry Mediator (TNFRSF14) and Latency-Associated Transcript during Herpes Simplex Virus 1 Latency

(2013) S. J. Allen et al.   JOURNAL OF VIROLOGY

Directional Spread of Alphaherpesviruses in the Nervous System

(2013) Tal Kramer et al.   Viruses-Basel

αvβ6- and αvβ8-Integrins Serve As Interchangeable Receptors for HSV gH/gL to Promote Endocytosis and Activation of Membrane Fusion

(2013) Tatiana Gianni et al.   PLoS Pathogens

Prophylactic, therapeutic and neutralizing effects of zinc oxide tetrapod structures against herpes simplex virus type-2 infection

(2012) Thessicar E. Antoine et al.   ANTIVIRAL RESEARCH

Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NF- B

(2012) V. Leoni et al.   JOURNAL OF VIROLOGY

Aptamer That Binds to the gD Protein of Herpes Simplex Virus 1 and Efficiently Inhibits Viral Entry

(2012) S. C. B. Gopinath et al.   JOURNAL OF VIROLOGY

A 3-O-Sulfated Heparan Sulfate Binding Peptide Preferentially Targets Herpes Simplex Virus 2-Infected Cells

(2012) M. M. Ali et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Membrane Proteins gE/gI and US9 Act Cooperatively To Promote Transport of Capsids and Glycoproteins from Neuron Cell Bodies into Initial Axon Segments

(2012) P. W. Howard et al.   JOURNAL OF VIROLOGY

Tin Oxide Nanowires Suppress Herpes Simplex Virus-1 Entry and Cell-to-Cell Membrane Fusion

(2012) James Trigilio et al.   PLoS One

Alphaherpesvirus axon-to-cell spread involves limited virion transmission

(2012) M. P. Taylor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amino acid differences in glycoproteins B (gB), C (gC), H (gH) and L(gL) are associated with enhanced herpes simplex virus type-1 (McKrae) entry via the paired immunoglobulin-like type-2 receptor α

(2012) Sona Chowdhury et al.   Virology Journal

A Herpes Simplex Virus 1 (McKrae) Mutant Lacking the Glycoprotein K Gene Is Unable To Infect via Neuronal Axons and Egress from Neuronal Cell Bodies

(2012) A. T. David et al.   mBio

The Membrane-Proximal Region (MPR) of Herpes Simplex Virus gB Regulates Association of the Fusion Loops with Lipid Membranes

(2012) S. S. Shelly et al.   mBio

Virostatic potential of micro–nano filopodia-like ZnO structures against herpes simplex virus-1

(2011) Yogendra Kumar Mishra et al.   ANTIVIRAL RESEARCH

Anti-heparan Sulfate Peptides That Block Herpes Simplex Virus Infectionin Vivo

(2011) Vaibhav Tiwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Binding of herpes simplex virus glycoprotein D to nectin-1 exploits host cell adhesion

(2011) Na Zhang et al.   Nature Communications

Phosphoinositide 3 kinase signalling may affect multiple steps during herpes simplex virus type-1 entry

(2010) V. Tiwari et al.   JOURNAL OF GENERAL VIROLOGY

The Ig-Like V-Type Domain of Paired Ig-Like Type 2 Receptor Alpha Is Critical for Herpes Simplex Virus Type 1-Mediated Membrane Fusion

(2010) Q. Fan et al.   JOURNAL OF VIROLOGY

A Single-Amino-Acid Substitution in Herpes Simplex Virus 1 Envelope Glycoprotein B at a Site Required for Binding to the Paired Immunoglobulin-Like Type 2 Receptor α (PILRα) Abrogates PILRα-Dependent Viral Entry and Reduces Pathogenesis

(2010) Jun Arii et al.   JOURNAL OF VIROLOGY

Reevaluating Herpes Simplex Virus Hemifusion

(2010) J. O. Jackson et al.   JOURNAL OF VIROLOGY

Cascade of Events Governing Cell-Cell Fusion Induced by Herpes Simplex Virus Glycoproteins gD, gH/gL, and gB

(2010) D. Atanasiu et al.   JOURNAL OF VIROLOGY

Bimolecular Complementation Defines Functional Regions of Herpes Simplex Virus gB That Are Involved with gH/gL as a Necessary Step Leading to Cell Fusion

(2010) D. Atanasiu et al.   JOURNAL OF VIROLOGY

Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus-1

(2010) Jun Arii et al.   NATURE

Crystal structure of the conserved herpesvirus fusion regulator complex gH–gL

(2010) Tirumala K Chowdary et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A role for heparan sulfate in viral surfing

(2009) Myung-Jin Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Herpes Simplex Virus Type 1 (HSV-1) Glycoprotein K(gK) is Essential for Viral Corneal Spread and Neuroinvasiveness

(2009) Andrew T. David et al.   CURRENT EYE RESEARCH

Class III viral membrane fusion proteins

(2009) Marija Backovic et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry

(2009) Jihan Akhtar et al.   FEBS Journal

Herpes Simplex Virus gD Forms Distinct Complexes with Fusion Executors gB and gH/gL in Part through the C-terminal Profusion Domain

(2009) Tatiana Gianni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Herpes Simplex Virus Utilizes the Large Secretory Vesicle Pathway for Anterograde Transport of Tegument and Envelope Proteins and for Viral Exocytosis from Growth Cones of Human Fetal Axons

(2009) M. Miranda-Saksena et al.   JOURNAL OF VIROLOGY

Myelin-associated glycoprotein mediates membrane fusion and entry of neurotropic herpesviruses

(2009) T. Suenaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpes simplex virus infection in pregnancy and in neonate: status of art of epidemiology, diagnosis, therapy and prevention

(2009) Elena Anzivino et al.   Virology Journal

PILRα Is a Herpes Simplex Virus-1 Entry Coreceptor That Associates with Glycoprotein B

(2008) Takeshi Satoh et al.   CELL

Surfen, a small molecule antagonist of heparan sulfate

(2008) M. Schuksz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA