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Addressing viral resistance through vaccines

Journal

FUTURE VIROLOGY
Volume 10, Issue 8, Pages 1011-1022

Publisher

FUTURE MEDICINE LTD
DOI: 10.2217/FVL.15.53

Keywords

antimicrobial resistance; antiviral resistance; cytomegalovirus; hepatitis C; HIV; influenza; vaccines; vaccine design; vaccine evaluation; vaccine implementation

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Funding

  1. Intramural NIH HHS [Z99 AI999999] Funding Source: Medline

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Antimicrobial resistance is a serious healthcare concern affecting millions of people around the world. Antiviral resistance has been viewed as a lesser threat than antibiotic resistance, but it is important to consider approaches to address this growing issue. While vaccination is a logical strategy, and has been shown to be successful many times over, next generation viral vaccines with a specific goal of curbing antiviral resistance will need to clear several hurdles including vaccine design, evaluation and implementation. This article suggests that a new model of vaccination may need to be considered: rather than focusing on public health, this model would primarily target sectors of the population who are at high risk for complications from certain infections.

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