Cytotoxic effects of chemotherapy on cancer and immune cells: how can it be modulated to generate novel therapeutic strategies?

The Role of Endoplasmic Reticulum Stress in Human Pathology

(2015) Scott A. Oakes et al.   Annual Review of Pathology-Mechanisms of Disease

PD-1/PD-L1 inhibitors

(2015) Joel Sunshine et al.   CURRENT OPINION IN PHARMACOLOGY

Immune Checkpoint Blockade in Cancer Therapy

(2015) Michael A. Postow et al.   JOURNAL OF CLINICAL ONCOLOGY

Cancer and the microbiota

(2015) W. S. Garrett   SCIENCE

Classification of current anticancer immunotherapies

(2015) Lorenzo Galluzzi et al.   Oncotarget

Adoptive Immunotherapy for Cancer or Viruses

(2014) Marcela V. Maus et al.   Annual Review of Immunology

Programmed death-1 pathway in cancer and autoimmunity

(2014) Ariel Pedoeem et al.   CLINICAL IMMUNOLOGY

γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer

(2014) Pin Wu et al.   IMMUNITY

The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells

(2014) Frédérique Végran et al.   NATURE IMMUNOLOGY

Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

(2014) Antonella Sistigu et al.   NATURE MEDICINE

Influence of cyclophosphamide and its metabolic products on the activity of peritoneal macrophages in mice

(2014) Krzysztof Bryniarski et al.   Pharmacological Reports

Diverse Mechanisms Regulate the Surface Expression of Immunotherapeutic Target CTLA-4

(2014) Helga Schneider et al.   Frontiers in Immunology

Consensus guidelines for the detection of immunogenic cell death

(2014) Oliver Kepp et al.   OncoImmunology

Trial Watch

(2014) Erika Vacchelli et al.   OncoImmunology

Cell-Death-Associated Molecular Patterns As Determinants of Cancer Immunogenicity

(2013) Sylvain Ladoire et al.   ANTIOXIDANTS & REDOX SIGNALING

Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists

(2013) T Yamazaki et al.   CELL DEATH AND DIFFERENTIATION

Molecular mechanisms of ATP secretion during immunogenic cell death

(2013) I Martins et al.   CELL DEATH AND DIFFERENTIATION

Crosstalk between ER stress and immunogenic cell death

(2013) Oliver Kepp et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Patient approach in advanced/metastatic renal cell carcinoma: focus on the elderly population and treatment-related toxicity

(2013) Elena Verzoni et al.   Future Oncology

Trabectedin mechanism of action: what’s new?

(2013) Maurizio D’Incalci   Future Oncology

Proapoptotic Chemotherapeutic Drugs Induce Noncanonical Processing and Release of IL-1  via Caspase-8 in Dendritic Cells

(2013) C. Antonopoulos et al.   JOURNAL OF IMMUNOLOGY

Bleomycin Exerts Ambivalent Antitumor Immune Effect by Triggering Both Immunogenic Cell Death and Proliferation of Regulatory T Cells

(2013) Hélène Bugaut et al.   PLoS One

Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment

(2013) N. Iida et al.   SCIENCE

The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide

(2013) S. Viaud et al.   SCIENCE

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Selective Activation of Intracellular Signalling Pathways in Dendritic Cells for Cancer Immunotherapy

(2012) Frederick Arce et al.   Anti-Cancer Agents in Medicinal Chemistry

Preconditioning Chemotherapy with Cisplatin Enhances the Antitumor Activity of Cytokine-Induced Killer Cells in a Murine Melanoma Model

(2012) Jing Chen et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Impact of chemotherapeutic agents on the immunostimulatory properties of human 6-sulfo LacNAc+(slan) dendritic cells

(2012) Rebekka Wehner et al.   INTERNATIONAL JOURNAL OF CANCER

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

(2012) L. Menger et al.   Science Translational Medicine

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival

(2011) Sylvain Ladoire et al.   JOURNAL OF PATHOLOGY

Identification and manipulation of tumor associated macrophages in human cancers

(2011) Moniek Heusinkveld et al.   Journal of Translational Medicine

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

Selective Depletion of CD4+CD25+Foxp3+Regulatory T Cells by Low-Dose Cyclophosphamide Is Explained by Reduced Intracellular ATP Levels

(2010) Jie Zhao et al.   CANCER RESEARCH

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

A Novel Chemoimmunomodulating Property of Docetaxel: Suppression of Myeloid-Derived Suppressor Cells in Tumor Bearers

(2010) K. N. Kodumudi et al.   CLINICAL CANCER RESEARCH

Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages

(2010) Ilia N. Buhtoiarov et al.   IMMUNOLOGY

Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress

(2010) I Martins et al.   ONCOGENE

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

(2010) M. P. Chao et al.   Science Translational Medicine

Interferon-Inducible CXC Chemokines Directly Contribute to Host Defense against Inhalational Anthrax in a Murine Model of Infection

(2010) Matthew A. Crawford et al.   PLoS Pathogens

Pneumoviruses infect eosinophils and elicit MyD88-dependent release of chemoattractant cytokines and interleukin-6

(2009) K. D. Dyer et al.   BLOOD

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Immunogenic death of colon cancer cells treated with oxaliplatin

(2009) A Tesniere et al.   ONCOGENE

Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy

(2008) Lei Zhang et al.   CLINICAL IMMUNOLOGY