The role of oncolytic virus immunotherapies to subvert cancer immune evasion

Expression of CCL19 from Oncolytic Vaccinia Enhances Immunotherapeutic Potential while Maintaining Oncolytic Activity

(2015) Jun Li et al.   NEOPLASIA

CpG Methylation of the IFNG Gene as a Mechanism to Induce Immunosupression in Tumor-Infiltrating Lymphocytes

(2014) P. C. J. Janson et al.   JOURNAL OF IMMUNOLOGY

From Scourge to Cure: Tumour-Selective Viral Pathogenesis as a New Strategy against Cancer

(2014) Carolina S. Ilkow et al.   PLoS Pathogens

Oncolytic bovine herpesvirus type 1 infects and kills breast tumor cells and breast cancer-initiating cells irrespective of tumor subtype

(2013) B P Cuddington et al.   CANCER GENE THERAPY

Antiviral and Antitumor T-cell Immunity in Patients Treated with GM-CSF-Coding Oncolytic Adenovirus

(2013) A. Kanerva et al.   CLINICAL CANCER RESEARCH

Regulating Cytokine Function Enhances Safety and Activity of Genetic Cancer Therapies

(2013) Hannah Chen et al.   MOLECULAR THERAPY

HDAC Inhibition Suppresses Primary Immune Responses, Enhances Secondary Immune Responses, and Abrogates Autoimmunity During Tumor Immunotherapy

(2013) Byram W Bridle et al.   MOLECULAR THERAPY

Oncolytic Adenovirus With Temozolomide Induces Autophagy and Antitumor Immune Responses in Cancer Patients

(2013) Ilkka Liikanen et al.   MOLECULAR THERAPY

Oncolytic Virotherapy and Immunogenic Cancer Cell Death: Sharpening the Sword for Improved Cancer Treatment Strategies

(2013) Samuel T Workenhe et al.   MOLECULAR THERAPY

Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy

(2013) Samuel T Workenhe et al.   MOLECULAR THERAPY

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer

(2013) Jeong Heo et al.   NATURE MEDICINE

Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy

(2013) S. T. Workenhe et al.   Cancer Immunology Research

Immune modulation of the tumor microenvironment for enhancing cancer immunotherapy

(2013) Christel Devaud et al.   OncoImmunology

Trial watch

(2013) Erika Vacchelli et al.   OncoImmunology

Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8+T-cell responses to anticancer vaccines

(2013) Byram W Bridle et al.   OncoImmunology

Primer on tumor immunology and cancer immunotherapy

(2013) Timothy J Harris et al.   Journal for ImmunoTherapy of Cancer

Targeting the Epigenome in Lung Cancer: Expanding Approaches to Epigenetic Therapy

(2013) Marko Jakopovic et al.   Frontiers in Oncology

Enhancement of the anti-melanoma response of Hu14.18K322A by αCD40 + CpG

(2012) Kory L. Alderson et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Oncolytic Virus and Anti-4-1BB Combination Therapy Elicits Strong Antitumor Immunity against Established Cancer

(2012) L. B. John et al.   CANCER RESEARCH

Systemic Combination Virotherapy for Melanoma with Tumor Antigen-Expressing Vesicular Stomatitis Virus and Adoptive T-cell Transfer

(2012) D. M. Rommelfanger et al.   CANCER RESEARCH

Exploiting the Mutanome for Tumor Vaccination

(2012) J. C. Castle et al.   CANCER RESEARCH

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma

(2012) Jose Pulido et al.   NATURE BIOTECHNOLOGY

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

Trial Watch

(2012) Lorenzo Galluzzi et al.   OncoImmunology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Targeted cancer immunotherapy with oncolytic adenovirus coding for a fully human monoclonal antibody specific for CTLA-4

(2011) J D Dias et al.   GENE THERAPY

Activating Systemic T-Cell Immunity Against Self Tumor Antigens to Support Oncolytic Virotherapy with Vesicular Stomatitis Virus

(2011) Phonphimon Wongthida et al.   HUMAN GENE THERAPY

Defining the critical hurdles in cancer immunotherapy

(2011) Bernard A Fox et al.   Journal of Translational Medicine

Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors

(2011) Timothy Kottke et al.   NATURE MEDICINE

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

Cancer Immunoediting: Integrating Immunity's Roles in Cancer Suppression and Promotion

(2011) R. D. Schreiber et al.   SCIENCE

COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function

(2010) Joris D Veltman et al.   BMC CANCER

Improved Clinical Outcome in Indolent B-Cell Lymphoma Patients Vaccinated with Autologous Tumor Cells Experiencing Immunogenic Death

(2010) R. Zappasodi et al.   CANCER RESEARCH

Selective Depletion of Foxp3+ Regulatory T Cells Improves Effective Therapeutic Vaccination against Established Melanoma

(2010) K. Klages et al.   CANCER RESEARCH

Reprogrammed Foxp3+ Regulatory T Cells Provide Essential Help to Support Cross-presentation and CD8+ T Cell Priming in Naive Mice

(2010) Madhav D. Sharma et al.   IMMUNITY

Blockade of CCL1 Inhibits T Regulatory Cell Suppressive Function Enhancing Tumor Immunity without Affecting T Effector Responses

(2010) D. B. Hoelzinger et al.   JOURNAL OF IMMUNOLOGY

Potentiating Cancer Immunotherapy Using an Oncolytic Virus

(2010) Byram W Bridle et al.   MOLECULAR THERAPY

Recognition of Virus Infection and Innate Host Responses to Viral Gene Therapy Vectors

(2010) Dmitry M Shayakhmetov et al.   MOLECULAR THERAPY

Expression of IFN-  Enhances Both Efficacy and Safety of Oncolytic Vesicular Stomatitis Virus for Therapy of Mesothelioma

(2009) C. L. Willmon et al.   CANCER RESEARCH

Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication

(2009) R. J. Prestwich et al.   CLINICAL CANCER RESEARCH

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Peptide inhibitors of transforming growth factor-β enhance the efficacy of antitumor immunotherapy

(2009) Diana Llopiz et al.   INTERNATIONAL JOURNAL OF CANCER

Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus

(2009) Byram W Bridle et al.   MOLECULAR THERAPY

Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells

(2008) Johanna K. Morales et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Chemical targeting of the innate antiviral response by histone deacetylase inhibitors renders refractory cancers sensitive to viral oncolysis

(2008) T. L.-A. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA