Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes

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Title
Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes
Authors
Keywords
Drug-induced liver injury, Unfolded protein response, Bile canaliculi deformation, Bile acid efflux, Heat shock protein, PI3K-AKT, Oxidative stress, HepaRG cells
Journal
FREE RADICAL BIOLOGY AND MEDICINE
Volume 115, Issue -, Pages 166-178
Publisher
Elsevier BV
Online
2017-12-02
DOI
10.1016/j.freeradbiomed.2017.11.017

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