Investigating pertussis toxin and its impact on vaccination

Epithelial Anion Transporter Pendrin Contributes to Inflammatory Lung Pathology in Mouse Models of Bordetella pertussis Infection

(2014) Karen M. Scanlon et al.   INFECTION AND IMMUNITY

Possible Options for New Pertussis Vaccines

(2014) B. D. Meade et al.   JOURNAL OF INFECTIOUS DISEASES

A Phase I Clinical Study of a Live Attenuated Bordetella pertussis Vaccine - BPZE1; A Single Centre, Double-Blind, Placebo-Controlled, Dose-Escalating Study of BPZE1 Given Intranasally to Healthy Adult Male Volunteers

(2014) Rigmor Thorstensson et al.   PLoS One

Toward a new vaccine for pertussis

(2014) John B. Robbins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pertussis resurgence: waning immunity and pathogen adaptation – two sides of the same coin

(2013) F. R. MOOI et al.   EPIDEMIOLOGY AND INFECTION

T-cell memory differentiation: insights from transcriptional signatures and epigenetics

(2013) Ben Youngblood et al.   IMMUNOLOGY

G Proteins Gαi1/3Are Critical Targets for Bordetella pertussis Toxin-Induced Vasoactive Amine Sensitization

(2013) Sean A. Diehl et al.   INFECTION AND IMMUNITY

Genome-Wide Gene Expression Analysis of Bordetella pertussis Isolates Associated with a Resurgence in Pertussis: Elucidation of Factors Involved in the Increased Fitness of Epidemic Strains

(2013) Audrey J. King et al.   PLoS One

Acellular pertussis vaccines protect against disease but fail to prevent infection and transmission in a nonhuman primate model

(2013) J. M. Warfel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of biomarkers to detect residual pertussis toxin using microarray analysis of dendritic cells

(2013) S.F.C. Vaessen et al.   VACCINE

Epigenetics and Bacterial Infections

(2013) H. Bierne et al.   Cold Spring Harbor Perspectives in Medicine

Relative Contribution of Th1 and Th17 Cells in Adaptive Immunity to Bordetella pertussis: Towards the Rational Design of an Improved Acellular Pertussis Vaccine

(2013) Pádraig J. Ross et al.   PLoS Pathogens

New pertussis vaccination approaches: en route to protect newborns?

(2012) Camille Locht et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Nonhuman Primate Model of Pertussis

(2012) Jason M. Warfel et al.   INFECTION AND IMMUNITY

Pertussis Toxin Exacerbates and Prolongs Airway Inflammatory Responses during Bordetella pertussis Infection

(2012) Carey E. Connelly et al.   INFECTION AND IMMUNITY

Selection and emergence of pertussis toxin promoter ptxP3 allele in the evolution of Bordetella pertussis

(2012) Connie Lam et al.   INFECTION GENETICS AND EVOLUTION

Number and Order of Whole Cell Pertussis Vaccines in Infancy and Disease Protection

(2012) Sarah L. Sheridan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Newly Emerging Clones of Bordetella pertussis Carrying prn2 and ptxP3 Alleles Implicated in Australian Pertussis Epidemic in 2008–2010

(2012) Sophie Octavia et al.   JOURNAL OF INFECTIOUS DISEASES

Bordetella Pertussis Toxin does not induce the release of pro-inflammatory cytokines in human whole blood

(2012) Christina Bache et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Bordetella pertussis infection induces a mucosal IL-17 response and long-lived Th17 and Th1 immune memory cells in nonhuman primates

(2012) J M Warfel et al.   Mucosal Immunology

Dual mechanism of protection by live attenuated Bordetella pertussis BPZE1 against Bordetella bronchiseptica in mice

(2012) Hana Kammoun et al.   VACCINE

The ins and outs of pertussis toxin

(2011) Camille Locht et al.   FEBS Journal

Adjuvant immunotherapy of C6 glioma in rats with pertussis toxin

(2011) Mario Orozco-Morales et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Identification and Characterization of the Carbohydrate Ligands Recognized by Pertussis Toxin via a Glycan Microarray and Surface Plasmon Resonance

(2010) Scott H. Millen et al.   BIOCHEMISTRY

Comparative genomics of prevaccination and modern Bordetella pertussis strains

(2010) Marieke J Bart et al.   BMC GENOMICS

Attenuated Bordetella pertussis vaccine strain BPZE1 modulates allergen-induced immunity and prevents allergic pulmonary pathology in a murine model

(2010) H. Kavanagh et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Attenuated Bordetella pertussis Protects against Highly Pathogenic Influenza A Viruses by Dampening the Cytokine Storm

(2010) R. Li et al.   JOURNAL OF VIROLOGY

Insight into Evolution of Bordetella pertussis from Comparative Genomic Analysis: Evidence of Vaccine-Driven Selection

(2010) Sophie Octavia et al.   MOLECULAR BIOLOGY AND EVOLUTION

Long-term immunity against pertussis induced by a single nasal administration of live attenuated B. pertussis BPZE1

(2010) Pascal Feunou Feunou et al.   VACCINE

Genetically Detoxified Pertussis Toxin Induces Th1/Th17 Immune Response through MAPKs and IL-10-Dependent Mechanisms

(2009) M. Nasso et al.   JOURNAL OF IMMUNOLOGY

Pertussis Toxin Signals through the TCR to Initiate Cross-Desensitization of the Chemokine Receptor CXCR4

(2009) O. D. Schneider et al.   JOURNAL OF IMMUNOLOGY

First report and detailed characterization of B. pertussis isolates not expressing pertussis toxin or pertactin

(2009) V. Bouchez et al.   VACCINE

Retrograde transport of pertussis toxin in the mammalian cell

(2008) Roger D. Plaut et al.   CELLULAR MICROBIOLOGY

Pathology and Pathogenesis of FatalBordetella pertussisInfection in Infants

(2008) Christopher D. Paddock et al.   CLINICAL INFECTIOUS DISEASES

Factors contributing to pertussis resurgence

(2008) Qiushui He et al.   Future Microbiology

Role of Neutrophils in Response to Bordetella pertussis Infection in Mice

(2008) C. Andreasen et al.   INFECTION AND IMMUNITY

Pertussis Toxin Inhibits Early Chemokine Production To Delay Neutrophil Recruitment in Response to Bordetella pertussis Respiratory Tract Infection in Mice

(2008) C. Andreasen et al.   INFECTION AND IMMUNITY