Identification of two benzopyrroloxazines acting as selective GPER antagonists in breast cancer cells and cancer-associated fibroblasts

Niacin activates the G protein estrogen receptor (GPER)-mediated signalling

(2014) Maria Francesca Santolla et al.   CELLULAR SIGNALLING

Endocrine Disruptor Agent Nonyl Phenol Exerts An Estrogen-like Transcriptional Activity on Estrogen Receptor Positive Breast Cancer Cells

(2014) A.A. Amaro et al.   CURRENT MEDICINAL CHEMISTRY

Contributions of Academic Laboratories to the Discovery and Development of Chemical Biology Tools

(2013) Donna M. Huryn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective GPER activation decreases proliferation and activates apoptosis in tumor Leydig cells

(2013) A Chimento et al.   Cell Death & Disease

Two Novel GPER Agonists Induce Gene Expression Changes and Growth Effects in Cancer Cells

(2012) R. Lappano et al.   CURRENT CANCER DRUG TARGETS

Recent Advances in the Rationale Design of GPER Ligands

(2012) C. Rosano et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis and Characterization of Tricarbonyl-Re/Tc(I) Chelate Probes Targeting the G Protein-Coupled Estrogen Receptor GPER/GPR30

(2012) Ritwik Burai et al.   PLoS One

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity

(2011) Megan K. Dennis et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

The G-protein-coupled estrogen receptor GPER in health and disease

(2011) Eric R. Prossnitz et al.   Nature Reviews Endocrinology

The Cholesterol Metabolite 25-Hydroxycholesterol Activates Estrogen Receptor α-Mediated Signaling in Cancer Cells and in Cardiomyocytes

(2011) Rosamaria Lappano et al.   PLoS One

Discovery of Selective Probes and Antagonists for G Protein-Coupled Receptors FPR/FPRL1 and GPR30

(2009) Jeffrey Arterburn et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Estrogen-Related Cancer Microenvironment of Breast Carcinoma

(2009) Yuri YAMAGUCHI et al.   ENDOCRINE JOURNAL

Chronic Treatment with the G Protein-Coupled Receptor 30 Agonist G-1 Decreases Blood Pressure in Ovariectomized mRen2.Lewis Rats

(2009) Sarah Hoffmann Lindsey et al.   ENDOCRINOLOGY

Chronic treatment with estrogen receptor agonists restores acquisition of a spatial learning task in young ovariectomized rats

(2009) R. Hammond et al.   HORMONES AND BEHAVIOR

The unfolding stories of GPR30, a new membrane-bound estrogen receptor

(2009) Marcello Maggiolini et al.   JOURNAL OF ENDOCRINOLOGY

Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis

(2009) Eric Blasko et al.   JOURNAL OF NEUROIMMUNOLOGY

Mechanisms of estrogen signaling and gene expression via GPR30

(2009) Eric R. Prossnitz et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

In vivo effects of a GPR30 antagonist

(2009) Megan K Dennis et al.   Nature Chemical Biology

The tumor microenvironment and its contribution to tumor evolution toward metastasis

(2008) Girieca Lorusso et al.   HISTOCHEMISTRY AND CELL BIOLOGY

The ins and outs of GPR30: A transmembrane estrogen receptor

(2008) Eric R. Prossnitz et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY