Article
Fisheries
Hua Liu, Jia-fang Xie, Hui Yu, Zheng Ma, Ying-Ying Yu, Ying Yang
Summary: This study sequenced the spleens of E. tarda-infected and non-infected yellow catfish to obtain miRNA and mRNA expression profiles, identifying large numbers of differentially expressed miRNAs and mRNAs and annotating key genes. Through integrated miRNA-mRNA analysis, immune-related miRNA-mRNA pairs were identified, and some differentially expressed miRNAs and mRNAs were verified. Further verification of selected mRNAs using in situ hybridization provided valuable information for understanding the mechanisms of yellow catfish defense against E. tarda infection.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Fisheries
Hee Jae Choi, Ji-Hoon Lee, Da Yeon Choi, Ji Hee Kim, Jin Man Cho, Hyuk Chu Kwon, Yue Jai Kang
Summary: This study evaluated the effects of betaine-supplemented feed on the growth and immunity of olive flounders. The results showed that betaine can promote growth and enhance immunity against bacterial infections in fish, potentially providing an alternative to conventional antibiotics in aquaculture.
JOURNAL OF FISH DISEASES
(2022)
Article
Fisheries
Abdelazeem M. Algammal, Mahmoud Mabrok, Mahmoud Ezzat, Khyreyah J. Alfifi, Aboelkheir M. Esawy, Nehal Elmasry, Reham M. El-Tarabili
Summary: The study investigated the prevalence, antibiotic resistance, and virulence gene distribution of natural E. tarda infection among Nile tilapia and African catfish. The results showed that most E. tarda isolates were multi-drug resistant and caused high mortality rates in challenged fish, posing a threat to fish farming in Egypt. Molecular-based detection is essential for controlling septicemic diseases in aquaculture.
Article
Microbiology
Tan-Trung Nguyen, Tran T. T. Xuan, To H. Ngoc, Le T. My Duyen, Tu Q. Vinh, Pham D. T. My, Hoang A. Hoang, Le P. Nga
Summary: This study reveals the existence of two novel bacteriophages infecting Edwardsiella ictaluri, vB_EiM_PVN06 and vB_EiA_PVN09, originating from the Mekong Delta in Vietnam. These bacteriophages exhibit distinct biological properties and show potential for phage therapy in the control of ESC disease.
Article
Infectious Diseases
Yuying Fu, Lishan Zhang, Huanhuan Song, Junyan Liao, Li Lin, Wenjia Jiang, Xiaoyun Wu, Guibin Wang
Summary: This study investigates the role of lysine acetylation and succinylation in the antibiotic resistance mechanism of Edwardsiella tarda. The results demonstrate that these post-translational modifications play important roles in bacterial antibiotic resistance and are enriched in various metabolic pathways. The findings provide insights into the mechanism of antibiotic resistance and may aid future research on the pathogenesis of this bacterium.
Article
Fisheries
Yilong Wang, Hang Xu, Boguang Sun
Summary: In this study, a lysosomal cysteine protease CsCatH was identified from half-smooth tongue sole. CsCatH and CsCatB were upregulated upon infection by E. tarda, a severe fish pathogen. Knockdown of CsCatH and CsCatB increased the replication of E. tarda and mitigated E. tarda-induced apoptosis in tongue sole tissues. These findings reveal the importance of CsCatH and CsCatB in the anti-bacterial immunity of tongue sole.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Cheng-dong Jin, Mo-fei Li
Summary: The study demonstrates that Omp1Et is a surface-located virulence factor of E. tarda, and recombinant Omp1Et can effectively induce immune protection as a subunit vaccine.
Article
Fisheries
Abigail R. Armwood, Matt J. Griffin, Bradley M. Richardson, David J. Wise, Cynthia Ware, Alvin C. Camus
Summary: This study clarifies the pathology of E. tarda, E. piscicida, and E. anguillarum infections in farm-raised catfish in the US. The results show that E. piscicida causes the most severe pathology, while E. anguillarum and E. tarda only warrant minimal concern. Additionally, some cross-protective effects were observed among E. piscicida, E. anguillarum, and E. ictaluri.
JOURNAL OF FISH DISEASES
(2022)
Article
Biochemistry & Molecular Biology
Huili Li, Boguang Sun, Shuai Jiang, Li Sun
Summary: The study used advanced antibody array technology to identify the expression pattern of cytokines induced by Edwardsiella tarda in a mouse infection model. Differentially expressed cytokines (DECs) were found at 6 and 24 hours post-infection, enriched in pathways associated with immunity, diseases, and infection. Key DECs, including IL6 and TNF-alpha, may play important roles in E. tarda infection.
Article
Immunology
Palanisamy Bothammal, Mohan Ganesh, Vellaisamy Vigneshwaran, Kumarasamy Anbarasu, Karuppiah Ponmurugan, Naif Abdullah Al-Dhabi, Kalimuthusamy Natarajaseenivasan
Summary: The study identified immune expressive proteins HflC, HflK, and YhcI which showed a 60% survivability in clearing Edwardsiella from the host. These immunoreactive proteins induced a strong immune response post-infection, leading to significant production of IL-10, IFN-gamma, Th1, and Th2 mediated mRNA expression, thus proving effective in vaccine production for edwardsiellosis.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Immunology
Lucia An, June L. Chan, Margaret Nguyen, Shangxin Yang, Jaime G. Deville
Summary: This case report illustrates the importance of recognizing rare bacterial infections and their potential for severe complications, especially in immunocompromised patients.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Article
Fisheries
Ruoxin Wang, Ping Han, Xiumei Liu, Xubo Wang
Summary: In this study, the role of TRAF genes in the immune response of Japanese flounder was investigated. Six TRAF genes were identified and analyzed, and their expression patterns were studied in different developmental stages and tissues. It was found that some of these genes showed differential expression under temperature stress and pathogen challenge, suggesting their involvement in the immune response. These findings provide insights into the molecular roles of TRAF genes in the regulation of immune and inflammatory responses in Japanese flounder.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Infectious Diseases
Abolfazl Gilani, Roham Sarmadian, Manijeh Kahbazi, Parsa Yousefichaijan
Summary: This case report describes a 4-year-old female patient with a urinary tract infection caused by E. tarda. The patient's symptoms were relieved after treatment with ceftriaxone and nitrofurantoin. This is the first reported case of E. tarda infection in Iran and highlights the need for necessary precautions to prevent further infections.
BMC INFECTIOUS DISEASES
(2022)
Article
Microbiology
Kohei Hasegawa, Murata Kenya, Kumiko Suzuki, Yoshihiko Ogawa
Summary: The study found that Edwardsiella tarda bacteremia typically occurs in patients with malignant underlying conditions, with biliary tract infections as the most common source and gastroenteritis as a possible atypical source. The mortality rate was low at 30 days but increased at 90 days due to unfavorable underlying conditions.
ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS
(2022)
Article
Agriculture, Dairy & Animal Science
Ibrahim Adeshina, Bilal Ahamad Paray, Eijaz Ahmed Bhat, Aishat D. Ibrahim, Lateef O. Tiamiyu
Summary: This study investigated the stimulatory effect of dietary alpha-lipoic acid (ALA) on the growth performance, antioxidant capacity, liver enzymes, immunity, and protection of African catfish against Edwardsiella tarda infection. The results showed that ALA-fortified diets significantly improved fish growth, feed consumption, and utilization, as well as hemato-biochemical, antioxidant, and immune indices. Furthermore, fish fed with ALA-enriched diets exhibited reduced mortality after E. tarda infection.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Article
Environmental Sciences
Mohamad Nor Azra, Mohd Iqbal Mohd Noor, Yeong Yik Sung, Elizabeth R. Lawrence, Mazlan Abd Ghaffar
Summary: This article presents a systematic mapping review protocol aimed at studying the impact of climate change on invasive species. By collecting and analyzing peer-reviewed articles and creating knowledge maps, the study aims to identify regions at higher risk of biological invasion as climate change progresses. The results are expected to aid in the future management of invasive species in the context of climate change.
ENVIRONMENTAL EVIDENCE
(2022)
Article
Environmental Sciences
Mohamad Nor Azra, Mohd Iqbal Mohd Noor, Jacqualyn Eales, Yeong Yik Sung, Mazlan Abd Ghaffar
Summary: This study aims to determine the impact of climate change on the physiology and behavior of crustaceans, specifically those important for aquaculture in Asia. The findings will provide evidence and recommendations for future research in this field.
ENVIRONMENTAL EVIDENCE
(2022)
Article
Microbiology
Meiaoxue Han, Guangfu Luo, Jianfeng He, Yantao Liang, Xuechao Chen, Gang Liu, Yue Su, Fuyue Ge, Hao Yu, Jun Zhao, Qiang Hao, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew McMinn, Min Wang
Summary: This study reports on the distribution of virioplankton and picoplankton in the Amundsen Sea of West Antarctica and their relationships with environmental factors. The upwelling of Circumpolar Deep Water (CDW) and the timing of ice-edge blooms were found to be the main factors controlling their distribution.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Pharmacology & Pharmacy
Gul-e-Saba Chaudhry, Abdah Md Akim, Yeong Yik Sung, Tengku Muhammad Tengku Sifzizul
Summary: Cancer is a complex and challenging disease, but the screening of plant and marine extracts may lead to the discovery of more effective anti-cancer compounds. Inducing apoptosis, a deeper mechanism of cell death, is essential for successful chemotherapy. Several plant and marine-derived anti-cancer compounds have been approved for clinical trials. Therefore, the development of new natural anti-cancer drugs is crucial.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Microbiology
Ruizhe Guo, Kaiyang Zheng, Lin Luo, Yundan Liu, Hongbing Shao, Cui Guo, Hui He, Hualong Wang, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Yu-Zhong Zhang, Yantao Liang, Andrew McMinn, Min Wang
Summary: A novel single-stranded DNA phage, vB_VpaM_PG19, infecting V. parahaemolyticus, was isolated and it represents a potential antimicrobial agent for pathogenic V. parahaemolyticus. It might belong to a new viral genus called Vimicrovirus.
MICROBIOLOGY SPECTRUM
(2022)
Review
Environmental Sciences
Mohamad N. Azra, Mohd Iqbal Mohd Noor, Yeong Yik Sung, Mazlan Abd Ghaffar
Summary: Research on the impact of climate change on aquatic production is limited. This study used bibliometric and scientometric analysis methods to assess the current status and trends of research on climate change and aquatic production. The findings highlighted ocean acidification as a crucial research topic for managing future aquatic production. The study also emphasized the need for international collaboration and integration of research from molecular biology, economics, and sustainability.
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2022)
Article
Green & Sustainable Science & Technology
Aisha Sajjad, Shaheen Begum, Muhammad Adnan, Gul-E-Saba Chaudhry, Muhammad Ibrahim, Mehwish Jamil Noor, Asma Jabeen, Sofia Khalid, Shazia Iram, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad
Summary: This research estimates the carbon stock of the subtropical broad-leaved evergreen scrub forest in Lehtrar, Pakistan. The results indicated that the forest had abundant biomass and an adequate carbon stock. However, deforestation and forest degradation activities posed a threat to its carbon sequestration capacity, highlighting the need for proper forest management practices.
Review
Agriculture, Dairy & Animal Science
Mohamad Nor Azra, Mohd Iqbal Mohd Noor, Juris Burlakovs, Muhammad Fuad Abdullah, Zulkiflee Abd Latif, Yeong Yik Sung
Summary: This study aimed to identify the current trends, research gaps, and literature development in the study of Artemia around the world. Using scientometric analyses, the study revealed that significant contributions in Artemia research primarily originated from the USA, Brazil, Spain, India, China, and Belgium. The study also identified the top keywords and emerging trends related to Artemia research, as well as generated co-citation clusters.
Article
Biochemistry & Molecular Biology
Ying-Chao Ma, Mei-Rong Gao, Huan Yang, Jun-Yao Jiang, Wei Xie, Wan-Ping Su, Bo Zhang, Yik-Sung Yeong, Wu-Yan Guo, Li-Ying Sui
Summary: This study aims to find more cost-effective and manageable ways of producing C-50 carotenoids. The results showed that using natural brine medium and adding glucose, sucrose, and lactose can enhance both biomass and carotenoid productivity. The best conditions for open fermentation were salinity 20-25%, rotation speed 150-200 rpm, and pH 7.0-8.2. The open fermentation of Halorubrum is a promising method for producing C-50 carotenoids.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2023)
Article
Ecology
Siti Zuraida Zulkipli, Chee Ping Tan, Ying Giat Seah, Hon Jung Liew, Yeong Yik Sung, Masashi Ando, Min Wang, Yantao Liang, Andrew McMinn, Wen Jye Mok
Summary: This study investigated mercury contamination in common commercial marine fish from the South China Sea. The muscle tissue mercury levels of four species were analyzed, and their trophic level was assessed. The results revealed variations in mercury concentrations among species, with Epinephelus heniochus having the highest concentration and Scomberomorus guttatus having the lowest. Factors such as size, food composition, and habitat were identified as the major influences on mercury levels in these fishes.
REGIONAL STUDIES IN MARINE SCIENCE
(2023)
Article
Environmental Sciences
Yajun Jing, Ruizhe Guo, Hongmin Wang, Yantao Liang, Yundan Liu, Yifei Feng, Qin Ma, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Yu-Zhong Zhang, Andrew McMinn, Min Wang, Jinyan Xing
Summary: A novel marine phage vB_VhaP_PG11 infecting Vibrio hangzhouensis was isolated from offshore waters of Qingdao, China. It is a double-stranded DNA phage and is related to two Vibrio phages with low homology. Phylogenetic analysis revealed that vB_VhaP_PG11 belongs to a new genus named Qingschitovirus in Schitoviridae. This study provides important information for understanding the interactions between Vibrio phages and their hosts and analyzing unknown viral sequences in metagenomic databases.
FRONTIERS IN MARINE SCIENCE
(2023)
Article
Virology
Fuyue Ge, Ruizhe Guo, Yantao Liang, Ying Chen, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew Mcminn, Min Wang
Summary: A novel Stutzerimonas stutzeri phage, vB_PstS_ZQG1, was isolated from the surface seawater of Qingdao, China. It has a unique morphology and genomic sequence, and shows low similarity with previously isolated phages or uncultured viruses, suggesting it belongs to a novel viral genus.
Article
Agriculture, Dairy & Animal Science
Sisilia Rivanda Arianto, Fendi Aprian Syah, Luthfiana Aprilianita Sari, Ayu Lana Nafisyah, Sulastri Arsad, Nadirah Musa
Summary: This study aimed to investigate the impact of the disinfectant benzalkonium chloride on goldfish, revealing that increasing concentrations of benzalkonium chloride resulted in decreased color brightness, restricted growth, intensified gill histopathological damage, and increased mortality rate. Thus, the research demonstrates the negative effects of conventional disinfectants on water and its organisms, emphasizing the necessity for further research on environmentally friendly alternatives.
Article
Marine & Freshwater Biology
Kaiyang Zheng, Yue Dong, Yantao Liang, Yundan Liu, Xinran Zhang, Wenjing Zhang, Ziyue Wang, Hongbing Shao, Yeong Yik Sung, Wen Jye Mok, Li Lian Wong, Andrew McMinn, Min Wang
Summary: This study systematically analyzed the genomes, taxonomic features, and distribution patterns of Pseudoalteromonas phages. A total of 143 Pseudoalteromonas-associated phage genomes were identified and assigned to 47 viral clusters. The prevalence of integrated proviruses and filamentous phages suggest the viral lysogenic life cycle in Pseudoalteromonas. These phages play a role in marine biogeochemical cycles and their abundance and distribution vary across polar areas and the deep sea. This study expands our understanding of marine Pseudoalteromonas phages and their interactions with their hosts.
MARINE LIFE SCIENCE & TECHNOLOGY
(2023)
Review
Pharmacology & Pharmacy
Gul-e-Saba Chaudhry, Abdah Md Akim, Naila Safdar, Azra Yasmin, Shaheen Begum, Yeong Yik Sung, Tengku Sifzizul, Tengku Muhammad
Summary: Analysis of cancer biomarkers has great potential in advancing our understanding of diseases at the molecular level and improving the accuracy and timeliness of diagnosis and follow-up care. Researchers are interested in using optical biosensors as a potential tool for early disease diagnosis. There is ongoing progress in the design of biosensors using various concepts.
JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH
(2022)
