Skeletal cell YAP and TAZ combinatorially promote bone development

Alterations to the Gut Microbiome Impair Bone Strength and Tissue Material Properties

(2017) Jason D Guss et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Crystal structure of TAZ-TEAD complex reveals a distinct interaction mode from that of YAP-TEAD complex

(2017) Hung Yi Kristal Kaan et al.   Scientific Reports

A Novel Technique for Accelerated Culture of Murine Mesenchymal Stem Cells that Allows for Sustained Multipotency

(2017) Courtney M. Caroti et al.   Scientific Reports

Osteogenesis imperfecta

(2016) Antonella Forlino et al.   LANCET

Yap1 Regulates Multiple Steps of Chondrocyte Differentiation during Skeletal Development and Bone Repair

(2016) Yujie Deng et al.   Cell Reports

Alternative Wnt Signaling Activates YAP/TAZ

(2015) Hyun Woo Park et al.   CELL

Yap and Taz regulate retinal pigment epithelial cell fate

(2015) J. B. Miesfeld et al.   DEVELOPMENT

Establishing Biomechanical Mechanisms in Mouse Models: Practical Guidelines for Systematically Evaluating Phenotypic Changes in the Diaphyses of Long Bones

(2015) Karl J Jepsen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanism of action of a WWTR1(TAZ)-CAMTA1 fusion oncoprotein

(2015) M R Tanas et al.   ONCOGENE

Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

(2015) Huabing Zhang et al.   Science Signaling

Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells

(2015) Alexandra Karystinou et al.   ARTHRITIS RESEARCH & THERAPY

Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

(2015) Minchul Kim et al.   Cell Reports

Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

(2015) Huabing Zhang et al.   Science Signaling

Improving the Estimate of the Effective Elastic Modulus Derived from Three-Point Bending Tests of Long Bones

(2014) Lampros C. Kourtis et al.   ANNALS OF BIOMEDICAL ENGINEERING

Osterix-Cre Transgene Causes Craniofacial Bone Development Defect

(2014) Li Wang et al.   CALCIFIED TISSUE INTERNATIONAL

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

Canonical Wnt signalling activates TAZ through PP1A during osteogenic differentiation

(2014) M R Byun et al.   CELL DEATH AND DIFFERENTIATION

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease

(2014) X. Varelas   DEVELOPMENT

Osx-Cre Targets Multiple Cell Types besides Osteoblast Lineage in Postnatal Mice

(2014) Jianquan Chen et al.   PLoS One

Shear Stress Induced by an Interstitial Level of Slow Flow Increases the Osteogenic Differentiation of Mesenchymal Stem Cells through TAZ Activation

(2014) Kyung Min Kim et al.   PLoS One

MT1-MMP-Dependent Control of Skeletal Stem Cell Commitment via a β1-Integrin/YAP/TAZ Signaling Axis

(2013) Yi Tang et al.   DEVELOPMENTAL CELL

Osteoblast-Targeted Overexpression of TAZ Increases Bone Mass In Vivo

(2013) Jae-Yeon Yang et al.   PLoS One

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOX2 Regulates YAP1 to Maintain Stemness and Determine Cell Fate in the Osteo-Adipo Lineage

(2013) Eunjeong Seo et al.   Cell Reports

Ultra-structural defects cause low bone matrix stiffness despite high mineralization in osteogenesis imperfecta mice

(2012) Maximilien Vanleene et al.   BONE

The importance of the intracortical canal network for murine bone mechanics

(2012) Philipp Schneider et al.   BONE

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Second harmonic generation microscopy for quantitative analysis of collagen fibrillar structure

(2012) Xiyi Chen et al.   Nature Protocols

The YAP and TAZ transcription co-activators: Key downstream effectors of the mammalian Hippo pathway

(2012) Wanjin Hong et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size

(2011) T. Heallen et al.   SCIENCE

Immature Osteoblast Lineage Cells Increase Osteoclastogenesis in Osteogenesis Imperfecta Murine

(2010) Haitao Li et al.   AMERICAN JOURNAL OF PATHOLOGY

The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Genetic and Transcriptional Control of Bone Formation

(2010) Amjad Javed et al.   Oral and Maxillofacial Surgery Clinics of North America

Transcriptional Control of Skeletogenesis

(2008) Gerard Karsenty   Annual Review of Genomics and Human Genetics

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

(2008) Xaralabos Varelas et al.   NATURE CELL BIOLOGY