Review
Energy & Fuels
Md Maruf Hossain Shuvo, Twisha Titirsha, Nazmul Amin, Syed Kamrul Islam
Summary: Modern healthcare is shifting towards individual-centric systems, with implantable and wearable medical devices playing a crucial role in making healthcare affordable and accessible. Harvesting energy from the human body and ambient environment is necessary for prolonging device lifetime and ensuring high-performance real-time operation.
Article
Chemistry, Multidisciplinary
Huifeng Wang, Samantha Huddleston, Jian Yang, Guillermo A. Ameer
Summary: Regenerative medicine aims to restore tissue and organ function, but faces barriers such as the lack of proregenerative biomaterials, a complex regulatory process, and user adoption challenges. Biodegradable polymers, although important in regenerative medicine, have limitations in their mechanical and degradation properties. Despite these limitations, a small number of biodegradable polymers have dominated the market for the past 50 years.
ADVANCED MATERIALS
(2023)
Article
Computer Science, Artificial Intelligence
Cai-Jin Ling, Ting Zeng, Vikramjit S. Dhaliwal
Summary: In recent years, medical professionals have widely adopted automated segmentation techniques for precise clinical decision-making. These techniques provide accurate information for effective decision-making in surgeries and treatment recommendations. This research study aims to evaluate the effectiveness of medical image segmentation algorithms and biomedical sensors in diagnosing and treating orthopedic diseases.
Review
Chemistry, Analytical
Denghui He, Yuanhui Cui, Fangchao Ming, Weiping Wu
Summary: This paper reviews and summarizes the progress of passive sensors in different materials, readout devices, and peripheral devices. It also discusses the applications of passive wireless sensors in contemporary life scenarios and the challenges for future developments.
Article
Biophysics
Tucker Stuart, Xiaoyang Yin, Shengjian Jammy Chen, Max Farley, Dylan Thomas McGuire, Nikhil Reddy, Ryan Thien, Sam DiMatteo, Christophe Fumeaux, Philipp Gutruf
Summary: We demonstrate a personalized, context-aware method for designing antennas, rectifiers, and wireless electronics that optimize electromagnetic and mechanical features based on human behavioral patterns and physiology. By implementing these methods, we can achieve continuous recording of high-fidelity biosignals for weeks without the need for human interaction.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Engineering, Electrical & Electronic
Benjamin G. Cary, John Z. Zhang, Christopher McHugh, Ioannis Kymissis, Elizabeth S. Olson, Hideko Heidi Nakajima, Jeffrey H. Lang
Summary: This article presents an implantable microphone for sensing the displacement of the umbo, and describes the structure and working principle of the sensor. The sensor enables the full implantation of assistive hearing devices, restoring hearing and improving sound localization in noisy environments.
IEEE SENSORS JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Semin Jo, Wonwoo Lee, Hojin Lee
Summary: Wireless power transfer (WPT) systems enable long-term operation and miniaturization of implantable devices by eliminating the need for battery replacement and wired power supplies. However, the practical application of wireless power transfer systems for implantable devices is challenging due to constraints and requirements of the human body, such as tissue reflection loss, small device size, and electromagnetic wave attenuation.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Daibin Jing, Hua Li, Xiao Ding, Wei Shao, Shaoqiu Xiao
Summary: This letter presents a compact and broadband circularly polarized implantable antenna for wireless implantable medical devices in the 2.4 GHz ISM band. The proposed antenna is designed with a modified square ring and a stacked parasitic structure, reducing the size and achieving circular polarization. It provides satisfactory axial ratio bandwidth and impedance bandwidth, with a peak realized gain of -24.7 dBi. The device-level performance and robustness of the antenna were evaluated in human phantoms and validated through measurement in minced pork.
IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS
(2023)
Review
Engineering, Biomedical
Kuntal Kumar Das, Bikramjit Basu, Pralay Maiti, Ashutosh Kumar Dubey
Summary: Piezoelectric nanogenerators (PENGs) hold great promise in personalized healthcare, providing self-powered sensors, drug delivery systems, and tissue regeneration. This comprehensive review examines the recent advancements in synthetic and nature-inspired piezoelectric materials for PENGs and discusses the potential of these materials and data science approaches to enhance personalized healthcare devices.
ACTA BIOMATERIALIA
(2023)
Article
Engineering, Electrical & Electronic
Xianbo Cao, Hiroyasu Sato, Kai-Da Xu, Wen Jiang, Shuxi Gong, Qiang Chen
Summary: Wireless power transfer technology has played a crucial role in the development of biomedical devices. A systematic method to improve the efficiency of wireless power transfer is proposed, which includes the application of a Fresnel zone plate and an air layer-artificial matching layer to reduce propagation loss and interface reflection. Simulation and experimental results demonstrate that the proposed method significantly enhances the efficiency of wireless power transfer.
IEEE TRANSACTIONS ON ANTENNAS AND PROPAGATION
(2023)
Review
Materials Science, Multidisciplinary
Jungang Zhang, Rupam Das, Jinwei Zhao, Nosrat Mirzai, John Mercer, Hadi Heidari
Summary: This article reviews comprehensive power solutions for cardiovascular implantable devices (cIMDs), with a focus on the prospects of wireless power transfer technology. By eliminating the need for fixed capacity batteries, wireless power transfer technology helps to reduce the risks and treatment costs associated with high-risk surgeries, and provides better biocompatibility. Additionally, the article covers related wireless data transmission and modulation-demodulation techniques.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Review
Engineering, Biomedical
Antonia Molloy, Kirsten Beaumont, Ali Alyami, Mahmut Kirimi, Daniel Hoare, Nosrat Mirzai, Hadi Heidari, Srinjoy Mitra, Steve L. Neale, John R. Mercer
Summary: Cardiovascular disease is the leading cause of mortality worldwide, and surgical interventions are often required. Development of cardiovascular implants with sensors and real-time monitoring capabilities can enable precision medicine-based healthcare. However, bringing implantable medical devices with wireless electronic sensing capabilities to market is complex and obstructive.
IEEE REVIEWS IN BIOMEDICAL ENGINEERING
(2022)
Review
Biochemistry & Molecular Biology
Lee Peyton, Alfredo Oliveros, Doo-Sup Choi, Mi-Hyeon Jang
Summary: Mental health disorders are linked to the neurobiology of the hippocampus and cortico-limbic structures, with disrupted neurogenesis contributing to conditions such as addiction, depression, and schizophrenia. Understanding neural regeneration in the hippocampus may offer new insights into treating mental health conditions.
EXPERIMENTAL AND MOLECULAR MEDICINE
(2021)
Article
Engineering, Electrical & Electronic
Ruizhi Chai, Ying Zhang
Summary: This paper proposes a Bayesian recursive multi-step prediction method for predicting overheating effects of implantable devices, achieving accurate predictions in a low complexity environment.
IEEE SENSORS JOURNAL
(2021)
Review
Chemistry, Multidisciplinary
Xiangui Ma, Wenyue Gao, Fangxin Du, Fan Yuan, Jing Yu, Yiran Guan, Neso Sojic, Guobao Xu
Summary: Electrochemiluminescence (ECL) combines electrochemical and chemiluminescent methods, used in clinical analysis and biological research. Efforts focus on enhancing sensitivity, portability, and affordability of ECL devices. The research aims to develop new electrodes, wireless power transfer (WPT) based devices, and novel bipolar electrochemistry.
ACCOUNTS OF CHEMICAL RESEARCH
(2021)
Article
Engineering, Electrical & Electronic
Salil Sidharthan Karipott, Praharsh Madappaly Veetil, Bradley D. Nelson, Robert E. Guldberg, Keat Ghee Ong
IEEE SENSORS JOURNAL
(2018)
Article
Engineering, Multidisciplinary
Bradley D. Nelson, Salil Sidharthan Karipott, Robert E. Guldberg, Keat Ghee Ong
MEASUREMENT SCIENCE AND TECHNOLOGY
(2020)
Article
Endocrinology & Metabolism
Brett S. Klosterhoff, Jarred Kaiser, Bradley D. Nelson, Salil S. Karipott, Marissa A. Ruehle, Scott J. Hollister, Jeffrey A. Weiss, Keat Ghee Ong, Nick J. Willett, Robert E. Guldberg
Review
Chemistry, Analytical
Bradley D. Nelson, Salil Sidharthan Karipott, Yvonne Wang, Keat Ghee Ong
Article
Biotechnology & Applied Microbiology
Sudhanshu Shekhar, Salil S. Karipott, Robert E. Guldberg, Keat G. Ong
Summary: In this study, a commercially available ME material was used to develop a sensor system that can monitor the attachment of anchorage-dependent mammalian cells. The results showed a linear relationship between sensor response and attached fibroblast cells on the sensor surface, and the system was capable of providing temporal profiles of cell growth in real-time at different stages of cell attachment and proliferation.
BIOTECHNOLOGY AND BIOENGINEERING
(2021)
Article
Engineering, Electrical & Electronic
Michael A. McGeehan, Salil Sidharthan Karipott, Michael E. Hahn, David C. Morgenroth, Keat Ghee Ong
Summary: An RGB LED-based optoelectronic sensor was designed in this study to measure multi-axial shear stresses, suitable for orthopedic devices such as prostheses or shoes. The sensor, simple and low-cost, determines shear forces by capturing reflected light intensity and demonstrated efficacy under benchtop testing conditions, showing promise for future medical applications.
IEEE SENSORS JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Salil Sidharthan Karipott, Bradley D. Nelson, Robert E. Guldberg, Keat Ghee Ong
Summary: A passively powered wireless sensor based on an LCR sensor is developed to measure tensile stress at suture anchors for soft tissue repair. The sensor is embedded within the suture anchor and consists of a strain gauge and a loop connector. The advantages of this sensor include small size, wireless detection, and battery-free operation, making it suitable for both short- and long-term implants.
IEEE SENSORS JOURNAL
(2022)
Article
Engineering, Electrical & Electronic
Michael A. McGeehan, Michael E. Hahn, Salil S. Karipott, Maryam Shuaib, Keat G. Ong
Summary: This paper introduces an optical-based sensor for measuring shear strain, which is suitable for biomedical and robotics applications. The sensor uses a red, green, and blue (RGB) light-emitting diode (LED) to project a cyclical pattern of RGB light onto a color pattern, and measures shear strain by analyzing the shift of the color pattern.
SENSORS AND ACTUATORS A-PHYSICAL
(2022)
Article
Engineering, Multidisciplinary
Michael McGeehan, Michael Hahn, Salil Karipott, Keat Ghee Ong
Summary: This paper presents the design, fabrication, and characterization of a miniaturized shear force sensor for biomedical applications. The sensor measures two-axis shear force by detecting displacement between a color panel and a light-sensing photodiode. It exhibited strong agreement with gold standard measurements and is well-suited for various biomedical applications.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2023)
Article
Engineering, Multidisciplinary
Salil S. Karipott, Karly Fear, Bradley Nelson, Kelly Leguineche, Angela Lin, Sudhanshu Shekhar, Robert E. Guldberg, Keat Ghee Ong
Summary: The study developed a bone fixation device that provides localized mechanical strains across a bone fracture site to promote healing. Results showed the device can provide highly focused and localized mechanical loading, with high off-axis compressive stiffness, and demonstrated good biocompatibility after being implanted in rodent subjects for 8 weeks.
ENGINEERING RESEARCH EXPRESS
(2021)