Elevated levels of the antimicrobial peptide LL-37 in hidradenitis suppurativa are associated with a Th1/Th17 immune response

Hidradenitis Suppurativa Is Characterized by Dysregulation of the Th17:Treg Cell Axis, Which Is Corrected by Anti-TNF Therapy

(2017) Barry Moran et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Intrinsic Defect in Keratinocyte Function Leads to Inflammation in Hidradenitis Suppurativa

(2016) Claire Hotz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cathelicidin regulates myeloid cell accumulation in adipose tissue and promotes insulin resistance during obesity

(2016) Quinte Braster et al.   THROMBOSIS AND HAEMOSTASIS

Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells

(2016) Audrey Gambade et al.   Oncotarget

LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway

(2016) Yoolhee Yang et al.   Stem Cell Research & Therapy

Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa

(2015) A.L. Lima et al.   BRITISH JOURNAL OF DERMATOLOGY

Dysregulated cytokine expression in lesional and nonlesional skin in hidradenitis suppurativa

(2015) G. Kelly et al.   BRITISH JOURNAL OF DERMATOLOGY

Antimicrobial peptide LL-37 promotes antigen-specific immune responses in mice by enhancing Th17-skewed mucosal and systemic immunities

(2015) Sae-Hae Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Pathophysiology of hidradenitis suppurativa: An update

(2015) Errol Prens et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Compartmentalized Cytokine Responses in Hidradenitis Suppurativa

(2015) Theodora Kanni et al.   PLoS One

Increased expression of heat shock protein 90 in keratinocytes and mast cells in patients with psoriasis

(2014) Masato Kakeda et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis

(2014) Roberto Lande et al.   Nature Communications

Human antimicrobial peptide LL-37 modulates proinflammatory responses induced by cytokine milieus and double-stranded RNA in human keratinocytes

(2013) Xue Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Decreased serum LL-37 and vitamin D3 levels in atopic dermatitis: relationship between IL-31 and oncostatin M

(2012) N. Kanda et al.   ALLERGY

Acne Inversa: Evaluating Antimicrobial Peptides and Proteins

(2012) Falk G. Bechara et al.   Annals of Dermatology

Lack of Neutrophil-Derived CRAMP Reduces Atherosclerosis in Mice

(2012) Yvonne Döring et al.   CIRCULATION RESEARCH

Avidity determines T-cell reactivity in abacavir hypersensitivity

(2012) Jacqueline Adam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Hidradenitis Suppurativa

(2012) Gregor B.E. Jemec   NEW ENGLAND JOURNAL OF MEDICINE

Elevated levels of tumour necrosis factor (TNF)-α, interleukin (IL)-1β and IL-10 in hidradenitis suppurativa skin: a rationale for targeting TNF-α and IL-1β

(2011) H.H. van der Zee et al.   BRITISH JOURNAL OF DERMATOLOGY

Immunohistological pointers to a possible role for excessive cathelicidin (LL-37) expression by apocrine sweat glands in the pathogenesis of hidradenitis suppurativa/acne inversa

(2011) V.U. Emelianov et al.   BRITISH JOURNAL OF DERMATOLOGY

Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function

(2011) Nicholas W. Kin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Expression of the IL-23/Th17 pathway in lesions of hidradenitis suppurativa

(2011) Christoph Schlapbach et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

The human cathelicidin, LL-37, induces granzyme-mediated apoptosis in cytotoxic T lymphocytes

(2010) Jamie S. Mader et al.   EXPERIMENTAL CELL RESEARCH