Article
Cardiac & Cardiovascular Systems
Majid Jadidi, William Poulson, Paul Aylward, Jason MacTaggart, Christian Sanderfer, Blake Marmie, Margarita Pipinos, Alexey Kamenskiy
Summary: This study found that vascular calcification occurs in different vascular zones and is influenced by demographics and risk factors, with age, creatinine level, body mass index being the most important contributors. Vascular morphometry did not directly affect calcium burden, and calcification in vascular zones developed asynchronously. Understanding the influence of demographics and risk factors on calcium prevalence can help with early identification of patients at higher risk of cardiovascular events.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2021)
Article
Clinical Neurology
Rebecca F. Gottesman, Sudha Seshadri
Summary: This article summarizes the relationship between traditional cardiovascular risk factors and stroke, while also exploring their impact on brain health. It emphasizes the importance of genes and biomarkers associated with Alzheimer's disease, as well as the influence of social determinants of health on brain health outcomes.
Article
Neurosciences
Candelaria Martin-Gonzalez, Ana Maria Godoy-Reyes, Pedro Abreu-Gonzalez, Camino Maria Fernandez-Rodriguez, Esther Martin-Ponce, Maria Jose Sanchez-Perez, Julio Cesar Alvisa-Negrin, Melchor Rodriguez-Gaspar, Emilio Gonzalez-Reimers
Summary: Heavy alcohol consumption leads to vascular calcification, which is associated with brain atrophy and cognitive impairment. This study aims to analyze the prevalence of vascular calcifications in alcoholics, their relationship with brain atrophy, and the role of sclerostin in these alterations.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Clinical Neurology
Dongwei Lu, Junfeng Liu, Andrew D. MacKinnon, Daniel J. Tozer, Hugh S. Markus
Summary: The study found a 7% prevalence of cerebral microbleeds in a large healthy community population, with distinct risk factors identified for microbleeds at different brain locations. Age was consistently associated with microbleeds in all locations, while hypertension, smoking, and alcohol consumption were specifically associated with deep microbleeds. The findings highlight the importance of understanding the diverse risk factors for cerebral microbleeds in different brain regions.
Article
Cardiac & Cardiovascular Systems
Shengnan Chen, Ning Li, Yajuan Gao, Hongli Jiang, Yan Shen
Summary: This study investigated the prevalence of vascular calcification based on the ankle-brachial index (ABI) value and analyzed the risk factors for vascular calcification in the general population. The results showed that the overall prevalence of vascular calcification was high and differed between males and females. The risk factors for vascular calcification also differed between genders, including age, body mass index, blood pressure, and lipid levels.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Clinical Neurology
Ruihong Yao, Liqing Yao, Amin Rao, Jibing Ou, Wenli Wang, Qinzhi Hou, Chunyan Xu, Bu-Lang Gao
Summary: This study investigated the prevalence and risk factors of stroke-related sarcopenia (SRS) in hospitalized patients receiving rehabilitation treatment. The results showed that significant risk factors for SRS include college degree or above, ICU stay, pneumonia, walking ability, cognitive impairment, aphasia, nasogastric feeding, age, and creatine kinase.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Hung-Jen Lin, Chih-Hao Chen, Ming-Wei Su, Chien-Wei Lin, Yu-Wen Cheng, Sung-Chun Tang, Jiann-Shing Jeng
Summary: This study investigated the effects of the NOTCH3 R544C variant and associated vascular risk factors on stroke in the Taiwanese population. The results showed that the NOTCH3 R544C variant alone increased the risk of stroke, but modifiable vascular risk factors also played a role in the occurrence of stroke in Taiwanese individuals carrying the NOTCH3 variant.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Clinical Neurology
Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Jie Zhao, Kai Chow Choi, Laveeza Butt, Alexander Yuk Lun Lau, Vincent Chung Tong Mok, Zoe Ching Man Kwok, David R. Thompson
Summary: This study investigated the prevalence of post-stroke cognitive impairment (PSCI) and its associated risk factors. The findings showed that advanced age, lower education levels, lower cognitive assessment scores, and higher fatigue and apathy scores were identified as strong risk factors for PSCI.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2023)
Article
Clinical Neurology
Xingyang Yi, Hong Chen, Yanfen Wang, Ming Yu, Hua Luo, Chun Wang, Wei Wei, Xiaorong Chen, Shaozhi Bao
Summary: A community-based survey in Sichuan, China found a high prevalence of high-risk population for stroke, with hypertension, physical inactivity, and dyslipidemia being the main risk factors. Individual and population-level interventions targeting these leading risk factors are crucial for stroke prevention.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Stefania Nannoni, Ali Scherz-Moussa Youma, Michael Amiguet, Ashraf Eskandari, Davide Strambo, Patrik Michel
Summary: In this study, 2% of AIS patients were found to have no established vascular risk factors (EVRFs), who were typically younger with more multiterritorial strokes, and had strong associations with PFO and contraceptive use. These patients showed worse long-term outcomes in terms of adjusted functional outcome, recurrence, and death.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Clinical Neurology
Stina Aam, Mari Nordbo Gynnild, Ragnhild Munthe-Kaas, Ingvild Saltvedt, Stian Lydersen, Anne-Brita Knapskog, Hege Ihle-Hansen, Hanne Ellekjaer, Rannveig Sakshaug Eldholm, Brynjar Fure
Summary: Post-stroke cognitive impairment (PSCI) is influenced by vascular risk factors, with atrial fibrillation, coronary heart disease, and previous stroke leading to more severe cognitive deficits. However, some cognitive domains show improvement from 3 to 18 months in patients without specific risk factors. Further research on interventions targeting vascular risk factors is needed to prevent PSCI.
FRONTIERS IN NEUROLOGY
(2021)
Article
Surgery
Matthew C. Chia, Yue-Yung Hu, Ruojia Debbie Li, Elaine O. Cheung, Joshua S. Eng, Tiannan Zhan, Malachi G. I. I. I. I. I. I. Sheahan, Karl Y. Bilimoria, Dawn M. Coleman
Summary: This study found that hazards such as mistreatment and duty-hour violations in vascular surgery training are associated with burnout symptoms. Nearly half of vascular surgery trainees reported experiencing symptoms of burnout.
JOURNAL OF VASCULAR SURGERY
(2022)
Review
Clinical Neurology
Gianna M. M. Fote, Sophia Raefsky, Kelton Mock, Amit Chaudhari, Mohammad Shafie, Wengui Yu
Summary: This review examines the pathophysiology and prevalence of intracranial artery calcifications (IAC), and the current evidence suggesting that IAC may be a useful tool for predicting stroke incidence, recurrence, and assessing the response to acute ischemic stroke therapy.
FRONTIERS IN NEUROLOGY
(2022)
Article
Medicine, General & Internal
Antonio Bellasi, Luca Di Lullo, Domenico Russo, Roberto Ciarcia, Michele Magnocavallo, Carlo Lavalle, Carlo Ratti, Maria Fusaro, Mario Cozzolino, Biagio Raffaele Di Iorio
Summary: In patients starting hemodialysis, the presence and extension of vascular calcification (VC) can predict the risk of all-cause death, regardless of the arterial site, and provide better risk assessment capabilities than traditional cardiovascular risk factors.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
K. Arun, Poornima N. Nambiar, Santhosh Kumar Kannath, Sapna E. Sreedharan, Sajith Sukumaran, Sankara Sarma, P. N. Sylaja
Summary: In patients with cryptogenic ischemic stroke, the prevalence of significant aortic plaques was found to be 15.7%. These patients were older and more likely to have risk factors like hypertension, coronary artery disease, and peripheral vascular disease. The significant plaque group had a significantly higher combined endpoint rate of stroke, TIA, and vascular death within one year (19.4% vs 6.2%).