Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2018, Issue 11, Pages 1326-1332Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201701711
Keywords
Synthetic methods; Cyanides; Potassium hexacyanoferrate(II); Triarylacrylonitrile; One-pot reaction; Multicomponent reactions
Categories
Funding
- National Natural Science Foundation of China [21462038]
- Key Laboratory of eco-environment Related Polymer Materials of Ministry of Education of China
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An efficient method for the one-pot multicomponent synthesis of triarylacrylonitriles from various aryl iodides directly by using calcium carbide as a concise acetylene source and potassium hexacyanoferrate(II) as an eco-friendly cyanide source is described. This protocol benefits from safe, inexpensive and easy-to-handle starting materials, good substrate tolerance and simple work-up procedure.
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