4.5 Article

Synthesis of 7-Bromo-1,3-diazapyrenes

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2018, Issue 30, Pages 4121-4127

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201800703

Keywords

Synthetic methods; Nitrogen heterocycles; Polycycles; Annulation; Thermolysis

Funding

  1. Ministry of Education and Science of the Russian Federation [02.a03.21.0008, 4.1196.2017/4.6]
  2. Russian Foundation for Basic Research [18-33-00849 mol_a]

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An efficient synthetic route towards previously inaccessible 7-bromo-1,3-diazapyrenes through an in-melt peri-cyclization of readily available 7-(5-bromo-3,4-dihydropyrimidin-4-yl)-1H-perimidines is described.

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