A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design

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Title
A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design
Authors
Keywords
Crystal structure, Inhibition properties, Benzoic acid derivatives, Serine-β-lactamase inhibitors, Fragments, Structure-guided drug design
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 145, Issue -, Pages 634-648
Publisher
Elsevier BV
Online
2017-12-30
DOI
10.1016/j.ejmech.2017.12.085

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