Discovery of 4-(( N -(2-(dimethylamino)ethyl)acrylamido)methyl)- N -(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia

Title
Discovery of 4-(( N -(2-(dimethylamino)ethyl)acrylamido)methyl)- N -(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
Authors
Keywords
-
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 150, Issue -, Pages 366-384
Publisher
Elsevier BV
Online
2018-03-20
DOI
10.1016/j.ejmech.2018.03.003

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