Article
Cardiac & Cardiovascular Systems
Wojciech Wanha, Jacek Bil, Michalina Kolodziejczak, Adam Kowalowka, Mariusz Kowalewski, Damian Hudziak, Radoslaw Gocol, Rafal Januszek, Tomasz Figatowski, Marek Milewski, Brunon Tomasiewicz, Piotr Kuebler, Bruno Hrymniak, Piotr Desperak, Lukasz Kuzma, Krzysztof Milewski, Bartlomiej Gora, Andrzej Los, Jan Kulczycki, Adrian Wlodarczak, Wojciech Skorupski, Marek Grygier, Maciej Lesiak, Fabrizio D'Ascenzo, Marek Andres, Pawel Kleczynski, Radoslaw Litwinowicz, Andrea Borin, Grzegorz Smolka, Krzysztof Reczuch, Marcin Gruchala, Robert J. Gil, Milosz Jaguszewski, Krzysztof Bartus, Piotr Suwalski, Slawomir Dobrzycki, Dariusz Dudek, Stanislaw Bartus, Mariusz Gasior, Andrzej Ochala, Alexandra J. Lansky, Marek Deja, Jacek Legutko, Elvin Kedhi, Wojciech Wojakowski
Summary: This study compared the safety and effectiveness of PCI and CABG for LM-ISR, showing lower risk of cardiac death in the short term with PCI, but no significant differences in MACCE in the long term, with fewer patients in the CABG group requiring TVR.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Michele Gallo, David Blitzer, Pietro L. Laforgia, Ilias P. Doulamis, Nils Perrin, Giacomo Bortolussi, Alvise Guariento, Alessandro Putzu
Summary: The study compared the outcomes of percutaneous coronary intervention (PCI) with drug-eluting stents and coronary artery bypass graft (CABG) for left main coronary artery disease. Results showed that PCI and CABG did not have significant differences in early or 5-year mortality, but exhibited varying rates of stroke, myocardial infarction, and repeat revascularization.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Medicine, General & Internal
Marc S. Sabatine, Brian A. Bergmark, Sabina A. Murphy, Patrick T. O'Gara, Peter K. Smith, Patrick W. Serruys, A. Pieter Kappetein, Seung-Jung Park, Duk-Woo Park, Evald H. Christiansen, Niels R. Holm, Per H. Nielsen, Gregg W. Stone, Joseph F. Sabik, Eugene Braunwald
Summary: A comparison of long-term outcomes between PCI with drug-eluting stents and CABG in patients with left main coronary artery disease showed no significant difference in 5-year all-cause mortality. However, differences were observed in rates of myocardial infarction, stroke, and repeat revascularisation, with higher risks associated with PCI. A Bayesian approach suggested a slight advantage favoring CABG in terms of mortality.
Article
Biology
Stefan Dan Cezar Mot, Adela Mihaela Serban, Ruxandra Stefana Beyer, Mihai Cocoi, Horia Iuga, Ioana Danuta Muresan, Simona Cozma, Alexandra Dadarlat-Pop, Raluca Tomoaia, Dana Pop
Summary: This study aimed to compare the effectiveness of PCI and CABG in patients with LMCS in terms of MACE occurrence. The results showed that for patients with LMCS, PCI with drug-eluting stents was as effective as CABG in terms of clinical death, myocardial infarction, repeat revascularization, and stroke at 1 year.
Review
Cardiac & Cardiovascular Systems
Mahin R. Khan, Waleed T. Kayani, Jason Pelton, Ahmed Ansari, David Paniagua, Umair Khalid, Ali Denktas, Hameem U. Changezi, Ahmad Munir, Ernesto Jimenez, Mahboob Alam, Hani Jneid
Summary: In patients with left ventricular systolic dysfunction (LVD), coronary artery bypass surgery (CABG) was associated with lower long-term mortality and revascularization rates compared to percutaneous coronary intervention (PCI), but had a higher risk of upfront stroke. However, the majority of data were observational studies, emphasizing the need for randomized trials.
CARDIOVASCULAR DRUGS AND THERAPY
(2021)
Article
Cardiac & Cardiovascular Systems
Ovidio De Filippo, Antonino Di Franco, Paolo Boretto, Francesco Bruno, Vincenzo Cusenza, Paolo Desalvo, Michelle Demetres, Andrea Saglietto, Luca Franchin, Francesco Piroli, Giorgio Marengo, Edoardo Elia, Volkmar Falk, Federico Conrotto, Torsten Doenst, Mauro Rinaldi, Gaetano Maria De Ferrari, Fabrizio D'Ascenzo, Mario Gaudino
Summary: This study compared the outcomes of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) for different lesion sites (ostial/shaft vs distal) in patients with unprotected left main coronary artery (ULMCA) disease. It found that for patients with distal ULMCA disease, CABG is associated with lower incidence of major adverse cardiovascular events (MACE) and revascularization compared with PCI.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Nicholas W. S. Chew, Chen-Han Ng, Gwyneth Kong, Keng-Siang Lee, Darren J. H. Tan, Oliver Zi-Hern Lim, Yip Han Chin, Bee Choo Tai, Tianyuan Gu, Seung-Jung Park, Duk-Woo Park, Marie-Claude Morice, Theodoros Kofidis, James W. L. Yip, Poay-Huan Loh, Koo-Hui Chan, Adrian F. Low, Chi-Hang Lee, Tiong-Cheng Yeo, Huay-Cheem Tan, Mark Y. Chan
Summary: This study compared percutaneous coronary intervention (PCI) with drug-eluting stents and coronary artery bypass grafting (CABG) in the treatment of left main coronary artery disease (LMCAD) and found no statistically significant difference in cumulative 10-year all-cause mortality between the two groups. However, PCI had a higher rate of unplanned revascularization within 5 years.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Piroze M. Davierwala, Chao Gao, Daniel J. F. M. Thuijs, Rutao Wang, Hironori Hara, Masafumi Ono, Thilo Noack, Scot Garg, Neil O'leary, Milan Milojevic, Arie Pieter Kappetein, Marie-Claude Morice, Michael J. Mack, Robert-Jan Van Geuns, David R. Holmes, Mario Gaudino, David P. Taggart, Yoshinobu Onuma, Friedrich Wilhelm Mohr, Patrick W. Serruys
Summary: This study found that in patients with three-vessel disease and/or left main coronary artery disease, multiple arterial grafting (MAG) may achieve lower long-term all-cause mortality compared to PCI; both MAG and single arterial grafting (SAG) were associated with significantly lower mortality than PCI in patients with 3VD, while no significant differences were observed between PCI and MAG or SAG in LMCAD patients.
EUROPEAN HEART JOURNAL
(2022)
Review
Cardiac & Cardiovascular Systems
Fatima Ashfaq, Tayyiba Ahmed Noor, Sahar Ashraf, Hasan Sohail, Jahanzeb Malik, Amna Ashraf, Waheed Ashraf
Summary: This study investigated the social determinants of clinical follow-up visits after LM-PCI and CABG and their impact on post-treatment care and outcomes. Data from adult patients who underwent these procedures between 2015 and 2022 were collected and analyzed. The study found that factors such as age, gender, type of procedure, government entitlement, disease severity, and peripheral arterial disease were associated with differences in follow-up visits between LM-PCI and CABG patients. LM-PCI patients had more hospitalizations, outpatient visits, and emergency visits compared to CABG patients.
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Wojciech Jan Skorupski, Marta Kaluzna-Oleksy, Przemyslaw Mitkowski, Wlodzimierz Skorupski, Stefan Grajek, Malgorzata Pyda, Aleksander Araszkiewicz, Maciej Lesiak, Marek Grygier
Summary: Periprocedural myocardial injury is common after left main percutaneous coronary interventions, but its prognostic significance remains unclear. This study suggests that isolated periprocedural troponin elevation is not clinically significant for long-term outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Cardiac & Cardiovascular Systems
Sangwoo Park, Seung-Jung Park, Duk-Woo Park
Summary: Left main coronary artery disease (LMCAD) is a high-risk subset of obstructive coronary artery disease. Coronary artery bypass grafting (CABG) has been the gold standard treatment for LMCAD, but percutaneous coronary intervention (PCI) has also evolved as a safe and reasonable alternative. However, there are still unresolved issues regarding revascularization strategy and management for LMCAD.
KOREAN CIRCULATION JOURNAL
(2023)
Review
Cardiac & Cardiovascular Systems
Nicholas W. S. Chew, Jin Hean Koh, Cheng Han Ng, Darren Jun Hao Tan, Jie Ning Yong, Chaoxing Lin, Oliver Zi-Hern Lim, Yip Han Chin, Denzel Ming Wei Lim, Koo Hui Chan, Poay-Huan Loh, Adrian Low, Chi-Hang Lee, Huay-Cheem Tan, Mark Chan
Summary: This study conducted a two-stage meta-analysis using reconstructed individual patient data to compare long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) for patients with multivessel disease (MVD) without left main (LM) involvement. The results showed that CABG had a lower cumulative all-cause mortality compared to PCI for MVD patients without LM involvement. However, in patients with moderate to high SYNTAX score, PCI had a significantly higher 10-year all-cause mortality compared to CABG.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Physiology
Amin Daoulah, Rasha Taha Baqais, Alwaleed Aljohar, Abdulkarim Alhassoun, Ahmad S. Hersi, Wael Almahmeed, Nooraldaem Yousif, Abdulaziz Alasmari, Mohammed Alshehri, Fakhreldein Eltaieb, Badr Alzahrani, Ahmed Elmahrouk, Amr A. Arafat, Ahmed Jamjoom, Khalid Z. Alshali, Reda Abuelatta, Waleed A. Ahmed, Abdulrahman H. Alqahtani, Turki Al Garni, Shahrukh Hashmani, Ziad Dahdouh, Wael Refaat, Hameedullah M. Kazim, Mohamed Ajaz Ghani, Haitham Amin, Niranjan Hiremath, Youssef Elmahrouk, Ehab Selim, Jairam Aithal, Mohammed A. Qutub, Mohamed N. Alama, Ahmed M. Ibrahim, Abdelmaksoud Elganady, Abdulwali Abohasan, Farhan M. Asrar, Tarek Farghali, Maryam Jameel Naser, Taher Hassan, Mohammed Balghith, Adnan Fathey Hussien, Ibrahim A. M. Abdulhabeeb, Osama Ahmad, Mohamed Ramadan, Ahmed A. Ghonim, Abeer M. Shawky, Husam A. Noor, Ejazul Haq, Abdulrahman M. Alqahtani, Faisal Al Samadi, Seraj Abualnaja, Mushira Khan, Sameer Alhamid, Amir Lotfi
Summary: This study compared the outcomes of PCI and CABG in patients with impaired and normal renal function. The results showed that PCI had a lower risk of in-hospital MACCE in patients with impaired renal function, but there were no significant differences in follow-up MACCE between PCI and CABG.
KIDNEY & BLOOD PRESSURE RESEARCH
(2023)
Review
Cardiac & Cardiovascular Systems
Shitao Feng, Mingli Li, Jiayue Fei, Anqin Dong, Wenli Zhang, Yanhua Fu, Yang Zhao
Summary: This meta-analysis compared the long-term outcomes of PCI and CABG in patients with multivessel coronary artery or left main coronary artery disease. The results showed that CABG was superior to PCI in 5-year survival rate among patients with MVCA, but there was no significant difference in 10-year survival rate. For patients with LMCA, there was no significant difference in 5-year or 10-year survival rate between CABG and PCI. More long-term trials are needed to further investigate the differences between the two techniques.
JOURNAL OF CARDIOTHORACIC SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Valentino Bianco, Suresh Mulukutla, Edgar Aranda-Michel, Danny Chu, David Kaczorowski, Johannes Bonatti, Pyongsoo Yoon, Dustin Kliner, Catalin Toma, Yisi Wang, Steve Koscumb, Floyd Thoma, Forozan Navid, Derek Serna-Gallegos, Ibrahim Sultan
Summary: This study compares the outcomes of multiarterial grafting and percutaneous coronary intervention (PCI) in patients with multivessel coronary disease. It found that multiarterial grafting is associated with fewer adverse events, improved survival, and reduced hospital readmissions for appropriate patients.
ANNALS OF THORACIC SURGERY
(2023)