Review
Biochemistry & Molecular Biology
Shima Nasri, Mohammad Bayat, Khudaidad Kochia
Summary: Compounds containing 1,2,4-triazole scaffolds play a crucial role in drug discovery, this review article summarizes their pharmacological significance and synthesis strategies, encouraging further research to discover new drug candidates.
MOLECULAR DIVERSITY
(2022)
Article
Biochemistry & Molecular Biology
Emmanouil Orfanakis, Aggeliki Koumentaki, Aikaterini Zoumi, Aggelos Philippidis, Peter C. Samartzis, Michalis Velegrakis
Summary: This study aims to detect benzo[a]pyrene residues in extra virgin olive oil using an easily adaptive optical methodology based on fluorescence spectroscopy, which does not require any sample pretreatment. The detection of benzo[a]pyrene even at low concentrations in the oil samples demonstrates the capability of fluorescence spectroscopy to ensure food safety.
Article
Biochemistry & Molecular Biology
Xingchen Dong, Siyi Wu, Zihuan Rao, Yaqian Xiao, Yan Long, Zhixiong Xie
Summary: Polycyclic aromatic hydrocarbons (PAHs) are common carcinogens, and benzo(a)pyrene is one of the most difficult high-molecular-weight (HMW) PAHs to remove. Biodegradation has been considered an ideal method for PAH pollutant elimination, but research on HMW PAHs, especially benzo(a)pyrene, is limited. This study focuses on the highly efficient benzo(a)pyrene-degrading strain BaP3, aiming to elucidate its high degradation efficiency mechanism and contribute to the understanding of the degradation mechanism of highly toxic PAHs and provide new solutions for practical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Environmental
Zuotao Zhang, Jiao Sun, Xiaoqiang Gong, Chongyang Wang, Hui Wang
Summary: A new sulfate-reducing bacterium, Desulforamulus aquiferis strain DSA, was found to degrade high molecular weight polycyclic aromatic hydrocarbons (HMW-PAHs) pyrene and benzo[a]pyrene, while reducing sulfate to sulfide. The metabolic processes for anaerobic pyrene and benzo[a]pyrene degradation were proposed based on detecting intermediates and analyzing the genome. This study provides new guidance for anaerobic HMW-PAHs degradation under sulfate-reducing conditions.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Xiaoxue Zhang, Xiaomin Wang, Yan Li, Guohui Ning, Qian Zhang, Xuena Zhang, Wei Zheng, Zhixin Yang
Summary: This study compared the biosorption, transmembrane transport, and biodegradation of Pyr and BaP by Bacillus sp. strain M1. The results showed that BaP had a higher biosorption efficiency and reached peak adsorption efficiency faster than Pyr. Both Pyr and BaP entered the cells by passive transport. In terms of biodegradation, BaP had a significantly higher efficiency than Pyr around days 5-7 of culture. Key enzymes involved in BaP and Pyr degradation were identified.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Chemistry, Multidisciplinary
Jingnan Jin, Yahui Shi, Baozhong Zhang, Dongjin Wan, Qingye Zhang, Ying Li
Summary: In this study, a BaP-degrading strain Pannonibacter sp. JPA3 was isolated from oil well production water, which could remove 80% of BaP at an initial concentration of 100 mg L-1 after 35 days of culture. The metabolites BaP-4,5-dihydrodiol, BaP-4,5-epoxide, 5-hydroxychrysene, and 2-hydroxy-1-naphthoic acid were identified in the biodegradation process. A dioxygenase model was built and molecular docking was performed to investigate the interaction mechanism between BaP and dioxygenase. A hypothesis for the progressive degradation mechanism of BaP by this strain was proposed based on the identification of downstream metabolites. In conclusion, this study provided an efficient BaP degrader and a comprehensive reference for the study of degradation mechanisms at the molecular level.
Article
Environmental Sciences
Qingxue Leng, Jun Mu, Guangfeng Yang
Summary: This study established highly efficient systems for anaerobic degradation of benzo[a]pyrene and identified the promoting effect of co-solvent and co-metabolic effect. The removal rate of benzo[a]pyrene at high concentrations was influenced by the co-solvent and co-metabolic effects.
ENVIRONMENTAL POLLUTION
(2021)
Article
Spectroscopy
K. Mucha, M. Pagacz-Kostrzewa, J. Krupa, M. Wierzejewska
Summary: This article investigates the interaction between 1,2,4-triazole and 3-amino-1,2,4-triazole with dinitrogen through both computational and experimental methods. The study reveals that these compounds can interact with dinitrogen in various specific ways. The analysis of infrared spectra suggests that 1:1 hydrogen-bonded complexes between the compounds and dinitrogen are predominant in low-temperature solid argon matrices.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Environmental Sciences
Claire Baranger, Isabelle Pezron, Laurence Lins, Magali Deleu, Anne Le Goff, Antoine Fayeulle
Summary: Hydrophobic organic soil contaminants like PAH are poorly mobile in soil and filamentous fungi are efficient in degrading them, but the mechanism of their mobilization needs further investigation. A microfluidic device was designed to study the uptake of BaP by fungi, revealing the uptake and storage mechanisms as well as the release of surface-active compounds.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Oumayma Kahla, Sondes Melliti Ben Garali, Fatma Karray, Manel Ben Abdallah, Najwa Kallel, Najla Mhiri, Hatem Zaghden, Badreddine Barhoumi, Olivier Pringault, Marianne Quemeneur, Marc Tedetti, Sami Sayadi, Asma Sakka Hlaili
Summary: The efficiency of a benthic diatom-associated bacteria in removing BaP and Flt was investigated in this study. Results showed a co-metabolic synergy between microalgae and associated bacteria in biodegrading PAHs, suggesting their potential application in the bioremediation of contaminated sites.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Chemistry, Multidisciplinary
Phuong N. Nguyen, Thi-Bich-Ngoc Dao, Trang T. Tran, Ngoc-Anh T. Tran, Tu A. Nguyen, Thao-Dang L. Phan, Loc P. Nguyen, Vinh Q. Dang, Tuan M. Nguyen, Nam N. Dang
Summary: The current study investigates the electrocatalytic CO2 reduction of [Re(CO)3Cl(N-N)], where N-N represents different ligands. The results demonstrate that these complexes show enhanced catalytic activity and stability for CO2 reduction, which provides a new approach for electrocatalytic CO2 reduction.
Article
Spectroscopy
Xiaotao Liu, Shanshan Xing, Yuanteng Xu, Ruiqing Chen, Chang Lin, Liangqia Guo
Summary: The addition of nitrogen-rich triazole group into the g-C3N4 motif significantly enhances the light absorption of g-C3N5 NSs, leading to higher efficiency of visible-light utilization. In vitro anticancer studies demonstrate the potential of g-C3N5 NSs as a low-toxic and biocompatible high-efficient photosensitizer for PDT.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Engineering, Environmental
Mukhtiar Ali, Xin Song, Qing Wang, Zhuanxia Zhang, Meng Zhang, Xing Chen, Zhiwen Tang, Xin Liu
Summary: In this study, it was found that the biodegradation rates of benzene and BaP co-contamination were significantly enhanced at elevated temperatures, with increased bioavailability and generation of ROS. The study also revealed that gram-positive bacteria exhibited higher enzymatic activities and PAH-RHD alpha gene expression, indicating their preference for long-term elevated temperatures. ROS species (O(2)(center dot-)and center dot OH) were detected and cleared by increased antioxidant enzyme activities. Soil properties were affected by temperature treatments, indicating metal-organic-associated reactions during TEB. Overall, the results highlight the importance of temperature in enhancing biodegradation under thermally enhanced biodegradation conditions.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Chemistry, Analytical
Demet Uzun
Summary: In this study, an electroanalytical method using DPV at 3AT coated GC electrode was developed to determine paracetamol. The electrochemical characterization and electron transfer behavior of the prepared electrode in a specific mixture were confirmed, and the effect of pH on the redox reaction of paracetamol was investigated. The developed electrode showed a detection limit of 0.043 mu M and was successfully applied in pharmaceutical samples.
Article
Engineering, Environmental
Linsheng Zhang, Jian Ruan, Zhiyan Lu, Zishuai Xu, Guanchao Lan, Jianlong Wang
Summary: This study investigates the thermal decomposition behavior and thermal hazard of 3-nitro-1,2,4-triazole-5-one (NTO) synthesis using various experimental methods. The outcomes provide important parameters and guidance for ensuring the safety of NTO during the reaction process, transportation, and preservation.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2022)
Article
Chemistry, Applied
Isabelle Delsarte, Francois Delattre, Catherine Rafin, Etienne Veignie
CARBOHYDRATE POLYMERS
(2018)
Article
Environmental Sciences
Antoine Fayeulle, Etienne Veignie, Reiner Schroll, Jean Charles Munch, Catherine Rafin
JOURNAL OF SOILS AND SEDIMENTS
(2019)
Article
Environmental Sciences
Isabelle Delsarte, Etienne Veignie, Yann Landkocz, Catherine Rafin
Summary: In this study, 28 strains of filamentous fungi were isolated from historically contaminated soil in northern France. Selected for their ability to use hexadecane as a sole carbon source and hydrophobic behavior, six strains showed significant dry biomass on hexadecane. Further experiments demonstrated the potential of P. brasilianum in reducing soil toxicity and F. solani in dissipating PCDD/F concentrations in contaminated soil microcosms. Additionally, the use of cardboard as a growing medium was found to be more efficient than poplar wood in this process. Further research is needed to explore the mechanisms involved in fungal dioxin dissipation.
SOIL & SEDIMENT CONTAMINATION
(2021)
Article
Engineering, Chemical
Etienne Veignie, Catherine Rafin
Summary: This study demonstrates the ability of the filamentous fungus Penicillium canescens to dissipate high-molecular-weight polycyclic aromatic hydrocarbons (PAH). Through bioaugmentation treatment, P.canescens significantly reduces the PAH content in soil, particularly high-molecular-weight PAH, and decreases soil toxicity while increasing the content of fulvic and humic acids.
Article
Environmental Sciences
Muriel Chaghouri, Cedric Gennequin, Lucette Haingomalala Tidahy, Fabrice Cazier, Edmond Abi-Aad, Etienne Veignie, Catherine Rafin
Summary: This study investigated the H2S removal performance of a fungi-based biofilter. The results showed that Trichoderma harzianum in symbiotic with H2S-specific bacteria can effectively eliminate H2S. This has significant implications for biogas valorization.
ENVIRONMENTAL TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Etienne Veignie, Claire Ceballos, Christophe Len, Catherine Rafin
Article
Chemistry, Multidisciplinary
Ana Maria Rosu, Cristina Gabriela Grigoras, Catherine Rafin, Etienne Veignie
SCIENTIFIC STUDY AND RESEARCH-CHEMISTRY AND CHEMICAL ENGINEERING BIOTECHNOLOGY FOOD INDUSTRY
(2017)