Development of new preclinical models to advance adrenocortical carcinoma research

Identification of Mutations in Cell-Free Circulating Tumor DNA in Adrenocortical Carcinoma: A Case Series

(2017) Sara G Creemers et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Long-Term Outcomes of Adjuvant Mitotane Therapy in Patients With Radically Resected Adrenocortical Carcinoma

(2017) Alfredo Berruti et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients

(2017) Ahmet Zehir et al.   NATURE MEDICINE

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

(2016) Siyuan Zheng et al.   CANCER CELL

Targeting heterogeneity of adrenocortical carcinoma: Evaluation and extension of preclinical tumor models to improve clinical translation

(2016) Constanze Hantel et al.   Oncotarget

H295R expression of melanocortin 2 receptor accessory protein results in ACTH responsiveness

(2015) Kazutaka Nanba et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study

(2015) Martin Fassnacht et al.   LANCET ONCOLOGY

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

(2015) Matthew T Chang et al.   NATURE BIOTECHNOLOGY

Joint MiRNA/mRNA Expression Profiling Reveals Changes Consistent with Development of Dysfunctional Corpus Luteum after Weight Gain

(2015) Andrew P. Bradford et al.   PLoS One

Adrenocortical Carcinoma

(2014) Tobias Else et al.   ENDOCRINE REVIEWS

Integrated genomic characterization of adrenocortical carcinoma

(2014) Guillaume Assié et al.   NATURE GENETICS

MutationTaster2: mutation prediction for the deep-sequencing age

(2014) Jana Marie Schwarz et al.   NATURE METHODS

Steroid and steroid glucuronide profiles in urine during pregnancy determined by liquid chromatography–electrospray ionization-tandem mass spectrometry

(2013) Sirkku E. Jäntti et al.   ANALYTICA CHIMICA ACTA

Establishment and Characterization of the First Pediatric Adrenocortical Carcinoma Xenograft Model Identifies Topotecan as a Potential Chemotherapeutic Agent

(2013) E. M. Pinto et al.   CLINICAL CANCER RESEARCH

Adrenocortical Carcinoma Is a Lynch Syndrome–Associated Cancer

(2013) Victoria M. Raymond et al.   JOURNAL OF CLINICAL ONCOLOGY

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Phase 2 trial of cixutumumab in children, adolescents, and young adults with refractory solid tumors: A report from the Children's Oncology Group

(2013) Brenda Weigel et al.   PEDIATRIC BLOOD & CANCER

Silencing Mutated β-Catenin Inhibits Cell Proliferation and Stimulates Apoptosis in the Adrenocortical Cancer Cell Line H295R

(2013) Sébastien Gaujoux et al.   PLoS One

Patient-derived tumour xenografts as models for oncology drug development

(2012) John J. Tentler et al.   Nature Reviews Clinical Oncology

Combination Chemotherapy in Advanced Adrenocortical Carcinoma

(2012) Martin Fassnacht et al.   NEW ENGLAND JOURNAL OF MEDICINE

ROCK Inhibitor and Feeder Cells Induce the Conditional Reprogramming of Epithelial Cells

(2011) Xuefeng Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Phase II study of weekly paclitaxel and sorafenib as second/third-line therapy in patients with adrenocortical carcinoma

(2011) Alfredo Berruti et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Association of adrenocortical carcinoma with familial cancer susceptibility syndromes

(2011) Tobias Else   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Human adrenocortical carcinoma cell lines

(2011) Tao Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Predicting the functional impact of protein mutations: application to cancer genomics

(2011) Boris Reva et al.   NUCLEIC ACIDS RESEARCH

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Development of an Integrated Genomic Classifier for a Novel Agent in Colorectal Cancer: Approach to Individualized Therapy in Early Development

(2010) T. M. Pitts et al.   CLINICAL CANCER RESEARCH

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

High Diagnostic and Prognostic Value of Steroidogenic Factor-1 Expression in Adrenal Tumors

(2010) Silviu Sbiera et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Steroid metabolome in fetal and maternal body fluids in human late pregnancy

(2010) Martin Hill et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Epidermal growth factor receptor in adrenocortical tumors: analysis of gene sequence, protein expression and correlation with clinical outcome

(2010) Patrick Adam et al.   MODERN PATHOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Recurrence of Adrenal Cortical Carcinoma Following Resection: Surgery Alone Can Achieve Results Equal to Surgery Plus Mitotane

(2009) Elizabeth G. Grubbs et al.   ANNALS OF SURGICAL ONCOLOGY

Safety, tolerability, and pharmacokinetics of the anti-IGF-1R monoclonal antibody figitumumab in patients with refractory adrenocortical carcinoma

(2009) Paul Haluska et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma

(2009) Sebastian Wortmann et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

SF-1 is a Diagnostically Useful Immunohistochemical Marker and Comparable to Other Sex Cord-Stromal Tumor Markers for the Differential Diagnosis of Ovarian Sertoli Cell Tumor

(2008) Chengquan Zhao et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Treatment of Advanced Adrenocortical Carcinoma with Erlotinib plus Gemcitabine

(2008) Marcus Quinkler et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM