Article
Endocrinology & Metabolism
Friso de Vries, Daniel J. Lobatto, Marco J. T. Verstegen, Pieter J. Schutte, Irene C. Notting, Mark C. Kruit, S. Faisal Ahmed, Alberto M. Pereira, Wouter R. van Furth, Nienke R. Biermasz
Summary: This study proposed a novel way to classify and report surgical outcomes, integrating efficacy and safety at the patient level. By presenting results in four outcome groups ranging from good to poor, the study highlights the importance of balancing efficacy and complications in surgical interventions.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Friso de Vries, Daniel J. Lobatto, Marco J. T. Verstegen, Pieter J. Schutte, Irene C. Notting, Mark C. Kruit, S. Faisal Ahmed, Alberto M. Pereira, Wouter R. van Furth, Nienke R. Biermasz
Summary: Transsphenoidal surgery is the standard treatment for hormone-secreting pituitary adenomas. This study proposes a novel way to classify and report surgical outcomes by integrating efficacy and safety at the patient level. The results show that surgical interventions can be presented in four categories, incorporating both efficacy and safety.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Clinical Neurology
Yasuyuki Kinoshita, Akira Taguchi, Atsushi Tominaga, Kazunori Arita, Fumiyuki Yamasaki
Summary: Recovery from AGHD after initial TSS is more likely in younger female patients with higher peak GH levels assessed by preoperative PPT. Patients aged <= 62.2 years and with a peak GH level of >= 0.74 μg/L based on preoperative PPT are likely to recover from AGHD.
JOURNAL OF NEUROSURGERY
(2021)
Article
Clinical Neurology
Yasuyuki Kinoshita, Akira Taguchi, Atsushi Tominaga, Kazunori Arita, Fumiyuki Yamasaki
Summary: There were no significant differences in perioperative complication rates between elderly and younger patients undergoing TSS for NFPA. Pseudocapsular resection did not increase surgical risks in either age group, but younger patients showed significant improvement in sGHD. Older age, rather than pseudocapsular resection, was the only factor predicting new development of sGHD post-TSS.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Article
Clinical Neurology
Zhijie Pei, Yi Fang, Shuwen Mu, Jun Li, Tianshun Feng, Kunzhe Lin, Shousen Wang
Summary: Perioperative assessment of adenohypophyseal hormones can improve therapeutic strategies and evaluate the prognosis of pituitary adenomas. Normalization of hormone levels facilitates overall assessment of the adenohypophysis.
NEUROSURGICAL FOCUS
(2022)
Article
Endocrinology & Metabolism
Jiun-Lin Yan, Mao-Yu Chen, Yao-Liang Chen, Chi-Cheng Chuang, Peng-Wei Hsu, Kuo-Chen Wei, Chen-Nen Chang
Summary: This study evaluated the outcomes of the endoscopic transsphenoidal approach as the primary treatment for somatotroph adenomas and investigated patients with suboptimal surgical results. Factors such as tumor size, preoperative GH level, and residual tumors were found to be associated with surgical failure. Octreotide showed good outcomes for treating DGSA patients, while SRS/EXRT generated good results for patients receiving secondary treatments when remission could not be reached after 6 months of TSA operation.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Clinical Neurology
Yinxing Huang, Meina Wang, Jianwu Wu, Kunzhe Lin, Shousen Wang, Fangfang Zhang
Summary: The aim of this study was to assess the factors influencing the occurrence of delayed hyponatremia after transsphenoidal surgery (TSS) in patients with a non-functional pituitary adenoma (NFPA). The results showed that delayed postoperative hyponatremia was independently associated with larger craniocaudal dimension, preoperative hyperprolactinemia, and larger preoperative pituitary stalk deviation angle.
FRONTIERS IN NEUROLOGY
(2022)
Article
Endocrinology & Metabolism
Mayo Ono, Izumi Fukuda, Akimi Soga, Shigeyuki Tahara, Akio Morita, Hitoshi Sugihara
Summary: Incidental pituitary tumors are generally smaller, found in older patients, have a lower incidence of hormone deficiency, and show better preservation of pituitary function postoperatively. Close observation and appropriate decision-making are important to prevent incidentalomas from progressing into symptomatic tumors.
Review
Medicine, Research & Experimental
Jacobo Kerbel, Amayrani Cano-Zaragoza, Rodrigo Espinosa-Dorado, Keren-Enid Garcia de la Torre, Moises Mercado
Summary: National registries are valuable tools to investigate rare conditions like acromegaly, providing insights into epidemiology, clinical presentation, diagnosis, treatment outcomes, and mortality. While single-center studies are more homogeneous, they are often limited by small sample sizes and lack statistical power.
ARCHIVES OF MEDICAL RESEARCH
(2023)
Article
Medicine, General & Internal
Yoon-Hee Choo, Youngbeom Seo, Oh-Lyong Kim
Summary: This study retrospectively analyzed the outcomes of the transsphenoidal approach for nonfunctioning pituitary adenomas treated at a single institute. The study found that the transsphenoidal approach is an effective and safe treatment, improving visual impairment and restoring endocrine function. Diabetes insipidus was the most common complication, and complete resection during surgery helped to lower the risk of recurrence.
ANNALS OF MEDICINE
(2022)
Article
Clinical Neurology
Lea M. Alhilali, Andrew S. Little, Kevin C. J. Yuen, Jae Lee, Timothy K. Ho, Saeed Fakhran, William L. White
Summary: In this study of 102 patients undergoing microscopic transsphenoidal resection of a pituitary adenoma, early postoperative MRI showed high sensitivity and specificity for detecting residual tumors, with better reliability than late postoperative MRI. Early MRI identified 4 residual tumors that were missed by intraoperative assessment and late MRI, providing important guidance for reoperation in select patients.
JOURNAL OF NEUROSURGERY
(2021)
Article
Oncology
Ralf Becker, Michal Hlavac, Gwendolin Etzrodt-Walter, Fabian Sommer, Christian Rainer Wirtz, Bernd Schmitz, Andrej Pala
Summary: Common complications of transsphenoidal surgery for pituitary macroadenomas include new-onset adrenocortical insufficiency and arginine vasopressin deficiency. Intraoperative thickening of the pituitary stalk can serve as an easy-to-acquire predictor of these endocrinological insufficiencies and aid in early detection. However, these findings still need to be validated in future prospective studies.
Article
Endocrinology & Metabolism
Alies J. Dekkers, Friso de Vries, Amir H. Zamanipoor Najafabadi, Emmy M. van der Hoeven, Marco J. T. Verstegen, Alberto M. Pereira, Wouter R. van Furth, Nienke R. Biermasz
Summary: This study retrospectively assessed the healthcare costs and cost drivers in perioperative care for pituitary tumour patients. The results showed that length of hospital stay and complications were the main drivers of costs, and certain baseline features were also associated with higher costs.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Chao Tao, Gang Cheng, Yunxiang Chen, Peiyuan Gu, Weixing Hu
Summary: This study retrospectively reviewed the tumor characteristics and surgical outcomes of a consecutive series of endoscopic endonasal approach pituitary adenomas resection mainly performed by a single author between March 2018 and June 2019. The results demonstrated that EEA is an effective and safe approach for resecting pituitary adenomas with satisfactory gross total resection rate, near-total resection rate, and endocrinological remission rate, while maintaining minimal nasal injury.
Article
Clinical Neurology
Christina E. Sarris, Scott T. Brigeman, Estelle Doris, Maggie Bobrowitz, Thomas Rowe, Eva M. Duran, Griffin D. Santarelli, Ryan M. Rehl, Garineh Ovanessoff, Monica C. Rodriguez, Kajalben Buddhdev, Kevin C. J. Yuen, Andrew S. Little
Summary: After implementing a comprehensive quality improvement program for pituitary surgery patients, there were significant improvements in patient outcomes, decreased outcome variability, and enhanced hospital financial performance. Future studies may provide further insight into disease remission, patient satisfaction, and how the surgeon learning curve impacts quality efforts.
JOURNAL OF NEUROSURGERY
(2021)
Article
Endocrinology & Metabolism
Noriaki Fukuhara, Kentaro Horiguchi, Hiroshi Nishioka, Hisanori Suzuki, Akira Takeshita, Yasuhiro Takeuchi, Naoko Inoshita, Shozo Yamada
Article
Clinical Neurology
Atsuhiro Nakagawa, Yoshikazu Ogawa, Kosaku Amano, Yudo Ishii, Shigeshi Tahara, Kentaro Horiguchi, Takakazu Kawamata, Shigetoshi Yano, Tatsuhiko Arafune, Toshikatsu Washio, Jun-ichi Kuratsu, Naokatsu Saeki, Yoshikazu Okada, Akira Teramoto, Teiji Tominaga
JOURNAL OF NEUROLOGICAL SURGERY PART A-CENTRAL EUROPEAN NEUROSURGERY
(2015)
Article
Clinical Neurology
Kentaro Horiguchi, Hiroshi Nishioka, Noriaki Fukuhara, Mitsuo Yamaguchi-Okada, Shozo Yamada
NEUROSURGICAL REVIEW
(2016)
Article
Clinical Neurology
Mine Seiichiro, Higuchi Yoshinori, Horiguchi Kentaro, Saeki Naokatu
JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE
(2016)
Article
Medicine, Research & Experimental
Tatsuma Matsuda, Kentaro Horiguchi, Yoshinori Higuchi, Toyoyuki Hanazawa, Yoshitaka Okamoto, Yasuo Iwadate
Article
Endocrinology & Metabolism
Tomoko Takiguchi, Hisashi Koide, Hidekazu Nagano, Akitoshi Nakayama, Masanori Fujimoto, Ai Tamura, Eri Komai, Akina Shiga, Takashi Kono, Seiichiro Higuchi, Ikki Sakuma, Naoko Hashimoto, Sawako Suzuki, Yui Miyabayashi, Norio Ishiwatari, Kentaro Horiguchi, Yukio Nakatani, Koutaro Yokote, Tomoaki Tanaka
BMC ENDOCRINE DISORDERS
(2017)
Article
Medicine, General & Internal
Hisashi Koide, Akina Shiga, Eri Komai, Azusa Yamato, Masanori Fujimoto, Ai Tamura, Takashi Kono, Akitoshi Nakayama, Tomoko Takiguchi, Seiichiro Higuchi, Ikki Sakuma, Hidekazu Nagano, Naoko Hashimoto, Sawako Suzuki, Yasuaki Takeda, Makoto Shibuya, Hiroshi Nishioka, Shozo Yamada, Naoko Inoshita, Norio Ishiwatari, Kentaro Horiguchi, Koutaro Yokote, Tomoaki Tanaka
Article
Oncology
Yasuo Iwadate, Tomoo Matsutani, Ayaka Hara, Seiichiro Hirono, Shiro Ikegami, Masayoshi Kobayashi, Daisuke Ito, Daisuke Kawauchi, Kentaro Horiguchi, Ado Tamiya, Yoshinori Higuchi
JOURNAL OF NEURO-ONCOLOGY
(2019)
Article
Clinical Neurology
Masaki Izumi, Yoshinori Higuchi, Maidinamu Yakufujiang, Takayuki Motoshima, Kentaro Horiguchi, Kyoko Aoyagi, Osamu Nagano, Toru Serizawa, Yasuo Iwadate, Iwao Yamakami
WORLD NEUROSURGERY
(2019)
Article
Clinical Neurology
Seiichiro Hirono, Daisuke Kawauchi, Masayoshi Kobayashi, Ryosuke Orimoto, Shiro Ikegami, Kentaro Horiguchi, Yasuo Iwadate
WORLD NEUROSURGERY
(2019)
Article
Clinical Neurology
Maidinamu Yakufujiang, Yoshinori Higuchi, Shogo Wakita, Kentaro Horiguchi, Shiro Ikegami, Yasuo Iwadate
EGYPTIAN JOURNAL OF NEUROSURGERY
(2020)
Article
Clinical Neurology
Tsubasa Okuyama, Kentaro Horiguchi, Yoshinori Higuchi, Tatsuma Matsuda, Akihiko Adachi, Eiichi Kobayashi, Yasuo Iwadate
INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT
(2019)
Article
Clinical Neurology
Seiichiro Hirono, Daisuke Kawauchi, Yoshinori Higuchi, Taiki Setoguchi, Kazunori Kihara, Kentaro Horiguchi, Ken Kado, Motoki Sato, Kazumasa Fukuda, Takao Nakamura, Naokatsu Saeki, Iwao Yamakami
JOURNAL OF NEUROLOGICAL SURGERY REPORTS
(2015)
Article
Clinical Neurology
Kentaro Horiguchi, Hiromu Kato, Hiroshi Nishioka, Noriaki Fukuhara, Hidehiko Takeda, Shozo Yamada
INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT
(2014)