Article
Chemistry, Analytical
Yihuan Song, Qingfang Ma, Heyong Cheng, Jinhua Liu, Yuanchao Wang
Summary: A method utilizing online solid-phase extraction coupled with high performance liquid chromatography and inductively coupled plasma mass spectrometry was developed for simultaneous enrichment and analysis of ultra-trace lead and mercury species in water. This method allows for efficient and accurate determination of lead and mercury species in water samples, with high enrichment factors and low LODs and LOQs. The method was successfully applied to analyze trace lead and mercury species in various types of water samples, showing promising results for unstable sample analysis.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Sergey S. Volynkin, Pavel A. Demakov, Olga V. Shuvaeva, Konstantin A. Kovalenko
Summary: Metal-organic frameworks (MOFs) are increasingly used in analytical chemistry for pre-concentration and determination of trace elements. A new methodology for speciation of inorganic and organic mercury in water was proposed, demonstrating high efficiency, low LODs, wide linear range, and acceptable analysis duration.
ANALYTICA CHIMICA ACTA
(2021)
Article
Biochemical Research Methods
Jing Yang, Lianfang Chen, Qingying Wang, Xiaolin Mei, Xiupei Yang, Feng Huo
Summary: A novel technique based on capillary electrophoresis (CE) was developed to measure nitroimidazole antibiotics (NIABs) in environmental water samples. UiO-66 was used as an adsorbent in dispersive solid-phase extraction (DSPE) for the separation and detection of five different NIABs. The CE diode array detection method was employed for analysis. The optimal extraction conditions were determined, and the results showed high detection limits and spike recoveries.
Article
Chemistry, Analytical
Kamal K. Jinadasa, Paloma Herbello-Hermelo, Elena Pena-Vazquez, Pilar Bermejo-Barrera, Antonio Moreda-Pineiro
Summary: A pre-concentration method for low mercury levels in seaweed was developed, utilizing an imprinted polymer for selective extraction and determination of mercury species. The method showed low detection limits, good repeatability, and was successfully applied to certified reference materials and edible seaweeds for analysis of methylmercury and Hg(II).
Article
Biochemistry & Molecular Biology
Yixuan Fan, Runze Yu, Yongfeng Chen, Yufeng Sun, Geoffrey I. N. Waterhouse, Zhixiang Xu
Summary: In this study, a sensitive capillary electrophoresis method based on molecularly imprinted solid-phase extraction was developed for the determination of histamine in foods. The method showed good linearity and was able to accurately measure histamine content in different samples.
Review
Chemistry, Applied
Petr Tuma, Frantisek Opekar, Pavel Dlouhy
Summary: This paper provides a comprehensive survey of using capillary and microchip electrophoresis with contactless conductivity detection for the analysis of drinking water, beverages, and food items. It highlights the analysis of food on microchips and modern trends such as dual-opposite injection. CE/(CD)-D-4 is characterized by its universality, analysis speed, simple sample preparation, and minimal sample consumption.
Article
Electrochemistry
Wenjuan Zhang, Fuxiu Yang, Jichao Xu, Lu Wang, Kaowen Zhou
Summary: An efficient method for simultaneous determination of nine preservatives in food samples was established using solid phase extraction (SPE) and capillary electrophoresis (CE). The optimized parameters for SPE and CE were determined, achieving good linear relationship, low detection limits and satisfactory sample recoveries.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2021)
Article
Chemistry, Analytical
Katarzyna Pytlakowska, Ewa Malicka, Ewa Talik, Anna Gagor
Summary: A selective method for determining mercury ions in various water samples was developed using nano-bismuth sulfide as a solid sorbent, ultrasound-assisted dispersive micro-solid phase extraction, and EDXRF technology. This method allows for highly sensitive detection of mercury ions at low concentrations, even in the presence of high concentrations of coexisting anions and cations typically found in surface waters.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Chemistry, Analytical
Isabel Lizcano Sanz, Francisco Javier Guzman Bernardo, Gregorio Castaneda Penalvo, Juana Rodriguez Flores
Summary: In this study, DSPE was used in combination with capillary electrophoresis for the determination of dabrafenib and trametinib in serum, showing good enrichment efficiency and low detection limits under optimized conditions. The method offers a simpler and less sophisticated alternative for drug monitoring in patients with metastatic melanoma.
MICROCHEMICAL JOURNAL
(2021)
Review
Chemistry, Analytical
Petr Tuma
Summary: Contactless conductivity detection (C4D) is a universal detection technique that plays a significant role in the analysis of clinical samples. It is particularly sensitive to low molecular weight biogenic substances and can directly quantify them in their native form, making it widely applicable.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Wei Gao, Yaxin Qin, Yaping Zang, Jiaming Zhu, Wei Chen, Shengqiang Tong, Yuqun Zeng, Chu Chu
Summary: In this study, a green and efficient strategy combining miniaturized matrix solid-phase dispersion and solid-phase extraction with capillary electrophoresis was proposed for the accurate determination of target analytes in a complicated matrix. The developed method demonstrated satisfactory linearity and was confirmed to have superior green potential for the determination of complex samples.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Chemistry, Analytical
Alina Kleindienst, Igor Zivkovic, Emmanuel Tessier, Alkuin Koenig, Larseric Heimburger-Boavida, Milena Horvat, David Amouroux
Summary: By assessing the measurement uncertainties, we validated the application of an indirect method for determining DMHg and suggested the potential for generating more precise and accurate DMHg data.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Maria Vergara-Barberan, Ernesto Francisco Simo-Alfonso, Jose Manuel Herrero-Martinez, Fernando Benavente
Summary: An online method combining aptamer affinity solid-phase extraction capillary electrophoresis-mass spectrometry (AA-SPE-CE-MS) was developed for the purification, preconcentration, separation, and characterization of beta-lactoglobulin (beta-LG) in food samples. The method utilized a sorbent prepared by immobilizing an aptamer against beta-LG onto magnetic bead particles. The method showed satisfactory linearity, with a low limit of detection, repeatability, and long microcartridge lifetime, demonstrating its potential for accurate food safety and quality control.
Article
Chemistry, Analytical
Wanxin Li, Jiaxin Sun, Yao Xin, Yu Han, Yanyang Sun, Aijun Li, Zhi Wang
Summary: A novel nanozyme was synthesized for the detection of resveratrol. This nanozyme exhibited excellent peroxidase-like activity and the colorimetric reaction could be completed within 20 minutes.
ANALYTICAL METHODS
(2023)
Article
Chemistry, Physical
Lijian Zhan, Yin Zhang, Wei Si, Jingjie Sha, Yunfei Chen
Summary: This study demonstrates a solid-state nanopore platform for label-free detection and separation of short single-stranded DNA fragments based on length-dependent translocation behaviors. The controllable selectivity of ssDNA can be achieved by tuning nanopore size, with a maximum selectivity limitation of 30nt.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Environmental Sciences
Ping Liu, Longwen Fu, Bowei Li, Mingsan Man, Yunxia Ji, Qi Kang, Xiyan Sun, Dazhong Shen, Lingxin Chen
Summary: A simple and low-cost microfluidic chip platform was developed for cultivating cells, embryos, and larvae of fish. It allows real-time observation of development and investigation of the effects of different dissolved oxygen on fish.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Chemistry, Analytical
Ping Li, Hao Fu, Zhenyu Bai, Xiaoyang Feng, Ji Qi, Xingliang Song, Xueping Hu, Lingxin Chen
Summary: An effective strategy is proposed to construct a highly sensitive ratiometric fluorescence sensing platform for microcystins (MCs) based on a dummy molecularly imprinted polymer using metformin as a template. The imprinted nanohybrids of carbon dots (CDs) combined with fluorescein isothiocyanate (FITC) are synthesized (CDs-FITC-SiO2@MIP), in which the CDs and FITC serve as assisted response signals and reference enhancement signals, respectively. This method has great potential for monitoring MCs in complex systems.
Article
Chemistry, Multidisciplinary
Zhiyang Zhang, Shixuan Yang, Rongfang Zhao, Jiadong Chen, Shasha Wang, Jaebum Choo, Lingxin Chen
Summary: This paper focuses on different strategies to achieve recyclable SERS substrates and their applications. The problems of nonrecyclable SERS substrates are discussed systematically. Two categories of methods, chemical-free cleaning methods and chemical-assisted cleaning methods, are summarized. Current challenges and potential strategies of recyclable SERS substrates are also proposed.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Rongchao Mei, Yunqing Wang, Xizhen Zhao, Shang Shi, Xiaoyan Wang, Na Zhou, Dazhong Shen, Qi Kang, Lingxin Chen
Summary: Skin interstitial fluid (ISF)-based microneedle (MN) sensing using surface-enhanced Raman scattering (SERS) tags allows for the tracking of acute peritonitis progression and evaluation of treatment efficacy.
Article
Chemistry, Analytical
Junping Xue, Jingxiu Zhang, Cuichi Yu, Maryam Arabi, Jinhua Li, Guisheng Li, Gangqiang Yang, Lingxin Chen, Zhihua Song
Summary: The molecular imprinting technique has been widely used to prepare novel stationary phases, and the resulting materials have shown good performance in separating different analytes based on their high selectivity, simple synthesis, and good chemical stability. However, the commonly used mono-template in synthesizing molecularly imprinted polymers-based stationary phases has limitations in column efficiency and analyte range. In this study, a multi-template strategy was used to prepare ginsenosides imprinted polymer-based stationary phase, which showed improved efficiency and broader analyte range. The resulting ginsenosides imprinted polymer-coated silica stationary phase exhibited good reproducibility, repeatability, and stability for seven days.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Environmental Sciences
Zhe Wang, Min Lv, Chu-Long Huang, Dong-Dong Zhang, Ruixia Han, Gang Li, Ling-Xin Chen
Summary: This study found that anthropogenic activities, such as urbanization and oil combustion, have a significant impact on the distribution and properties of dissolved organic matter (DOM) in intertidal sediments. The release of organic matters from urbanization and the combustion of oil contribute to the higher concentration of aromatic compounds in the sediments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Analytical
Jinglong Han, Huajun Liu, Ji Qi, Jiawen Xiang, Longwen Fu, Xiyan Sun, Liyan Wang, Xiaoyan Wang, Bowei Li, Lingxin Chen
Summary: A novel, simple and effective visual fluorescent sensing paper-based chip was developed for the ultrasensitive detection of mercury ions in environmental water. The method has a low detection limit and fast response time, and successfully achieved trace spiking detection of various water sources.
Article
Chemistry, Analytical
Yan Huang, Lili Fu, Junjun Hou, Lingxiao Wang, Mingzhao Sun, Xiao Sun, Xiaoyan Wang, Lingxin Chen
Summary: Researchers designed and synthesized a nanocomposite RCDs@MnO2 to improve the hypoxic environment of tumors and enhance the efficacy of photodynamic therapy. The nanocomposite could generate 1O2 to achieve the purpose of photodynamic therapy and exhibit fluorescence off-on function in tumor cells and tissues. The results showed that RCDs@MnO2 has the potential to be applied in fluorescence imaging and significantly improve the photodynamic therapy of tumors, both in vitro and in vivo.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Peijun Chai, Xuhui Geng, Ruirui Zhu, Wenpu Wu, Xuesong Wang, Jinhua Li, Longwen Fu, Hongdan Wang, Wanhui Liu, Lingxin Chen, Zhihua Song
Summary: In this study, a novel stationary phase based on carbon dots (CDs), molecularly imprinted polymer (MIP) layer, and silica beads was synthesized to improve the chromatographic separation of polar compounds. The MIP-CDs/SiO2 stationary phase exhibited superior separation efficiency compared to other stationary phases tested, and its chromatographic performance was thoroughly assessed using a variety of compounds. The results showed that the MIP-CDs/SiO2 column combined the desirable properties of MIPs, CDs, and silica microbeads, making it a promising tool in separation science and chromatography-based techniques.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Yixuan Wu, Qian Yu, Younju Joung, Chang Su Jeon, Seunghyun Lee, Sung Hyun Pyun, Sang-Woo Joo, Lingxin Chen, Jaebum Choo
Summary: This study reports the development of a reproducible and highly sensitive surface-enhanced Raman scattering (SERS) substrate using a butanol-induced self-assembly of gold nanoparticles (AuNPs) and its application as a rapid diagnostic platform for SARS-CoV-2. The substrate showed strong electromagnetic enhancement of the Raman signals, enabling the detection of SARS-CoV-2 with a very low limit of detection (LoD) of 3.1 x 10(-15) M. This method provides sufficient sensitivity for SARS-CoV-2 screening assay and reduces the diagnostic time significantly. The results suggest the potential of this approach for developing rapid diagnostic platforms for other biomolecules and infectious diseases.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Ji Qi, Bowei Li, Dong Lin, Zhiqiang Du, Longwen Fu, Xiaoyan Wang, Zhiyang Zhang, Liqiang Luo, Lingxin Chen
Summary: To overcome the distortion of fluorescent images by mobile devices, a dual-mode strategy was developed to achieve undistorted visual fluorescent sensing on & mu;PAD by manipulating the coffee-ring effect of the fluid sample. By dividing the resulting fluorescence image into 600 pixels and using a fluorescent probe, accurate quantitative information was obtained to avoid image distortion. This strategy, combined with a small imaging box and a smartphone, allows for rapid testing of histidine in human urine and improved antidistortion for visual fluorescent sensing.
ANALYTICAL CHEMISTRY
(2023)
Article
Biophysics
Liyan Bi, Huangruici Zhang, Wenchao Hu, Jiadong Chen, Yixuan Wu, Hao Chen, Bingqian Li, Zhiyang Zhang, Jaebum Choo, Lingxin Chen
Summary: In this study, a novel M13 phage-based SERS nanocarrier was developed for the detection and inactivation of E. coli. The M13 phage was used as a biological scaffold to conjugate with Au@Ag core-shell nanorods (Au@AgNR) and specifically target E. coli. The proposed SERS probe showed a detection limit of 0.5 cfu/mL and high antibacterial efficiency of approximately 90% against E. coli.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Engineering, Environmental
Liyan Wang, Jialuo Yu, Xiaoyan Wang, Jinhua Li, Lingxin Chen
Summary: Environment pollution is a global issue that requires high-performance adsorbent materials for effective removal and remediation. Nanocomposites have emerged as a powerful tool for pollutant removal due to their superior adsorption performances. Among them, molecular imprinting-based nanocomposites with tailor-made binding sites have drawn great research interests in the field of environmental pollutants removal. This article provides a summary of the general fabrication and typical components of molecular imprinting-based nanocomposite adsorbents and discusses synthesis strategies for enhancing the adsorption performances, serving as a background for future research.
JOURNAL OF HAZARDOUS MATERIALS LETTERS
(2023)
Article
Environmental Sciences
Suyu Ren, Xiaojie Jin, Tadiyose Girma Bekele, Min Lv, Jing Ding, Feng Tan, Lingxin Chen
Summary: This study developed a reliable sampling approach, using DGT with XAD-2 as the binding agent, for monitoring 4-MBC in coastal waters. The diffusion coefficients of 4-MBC in freshwater and artificial seawater were determined and the XAD-2 binding gel showed rapid adsorption to 4-MBC. Field deployment showed consistent results with grab sampling, and the DGT method is suitable for seasonal monitoring, source identification, and risk assessment of 4-MBC in coastal waters.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Jing Ding, Zhaoqin Liang, Min Lv, Xiuyu Li, Shuang Lu, Suyu Ren, Xiaoyong Yang, Xiaoqiang Li, Chen Tu, Dong Zhu, Lingxin Chen
Summary: This study investigates the effects of soil aging on the toxicity of microplastics to soil fauna. The results show that soil aging slightly alters the surface properties and morphology of microplastics, and significantly affects the release of additives. Additionally, a less diverse microbial community is formed on the surface of microplastics compared to the surrounding soils. Aged microplastics have a significant impact on the reproduction of soil worms, particularly those aged in soil with manure, and disrupt their gut microbiota. Changes in biofilm features and leaching properties of microplastics during aging are the main contributing factors to these shifts. This study provides preliminary insights into the role of soil aging in the toxicity of microplastics to soil fauna.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
