Journal
ELECTROPHORESIS
Volume 40, Issue 8, Pages 1140-1143Publisher
WILEY
DOI: 10.1002/elps.201800123
Keywords
Dielectric film; Impedance glow cytometer; Lab-on-PCB; Microfluidic impedance sensor; Red blood cells
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Microfluidic impedance pulse sensor has emerged as an easily handled and low-cost platform in the electrical analysis of biological cells. In the conventional method, impedance sensor demanded expensive patterning metal electrodes on the substrate, which are directly in touch with electrolytes in order to measure the microfluidic channel impedance change. In this article, a cost-effective microfluidic impedance sensor built upon a dielectric film coated printed circuit board is introduced. Impedance electrodes are protected by a dielectric film layer from electrochemical erosion between electrodes and electrolyte. Human red blood cells from adult and neonatal were utilized to demonstrate the feasibility of the proposed device in the electroanalysis of biological cells.
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