Ursolic acid derivatives as potential antidiabetic agents: In vitro , in vivo , and in silico studies

Antidiabetic effect of Achillea millefollium through multitarget interactions: α-glucosidases inhibition, insulin sensitization and insulin secretagogue activities

(2018) Fabiola Chávez-Silva et al.   JOURNAL OF ETHNOPHARMACOLOGY

In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives

(2016) Litzia Cerón-Romero et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The mechanism of action of ursolic acid as insulin secretagogue and insulinomimetic is mediated by cross-talk between calcium and kinases to regulate glucose balance

(2015) Allisson Jhonatan Gomes Castro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Chalcones and their therapeutic targets for the management of diabetes: Structural and pharmacological perspectives

(2015) Debarshi Kar Mahapatra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition

(2014) Juan José Ramírez-Espinosa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vitro and in vivo evaluation of the antidiabetic activity of ursolic acid derivatives

(2014) Pan-Pan Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Ursolic Acid Induces Apoptosis Through Mitochondrial Intrinsic Pathway and Suppression of ERK1/2 MAPK in HeLa Cells

(2014) Yanhong Li et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Antibacterial and Antioxidant Activities of Ursolic Acid and Derivatives

(2014) Patrícia do Nascimento et al.   MOLECULES

Serotonergic and noradrenergic systems are implicated in the antidepressant-like effect of ursolic acid in mice

(2014) André R.S. Colla et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Synthesis of Isosteric Triterpenoid Derivatives and Antifungal Activity

(2013) Adrine Innocente et al.   Chemical Biology & Drug Design

Vasorelaxant activity of some structurally related triterpenic acids from Phoradendron reichenbachianum (Viscaceae) mainly by NO production: Ex vivo and in silico studies

(2012) Maria Yolanda Rios et al.   FITOTERAPIA

Antidepressant-like effect of ursolic acid isolated from Rosmarinus officinalis L. in mice: Evidence for the involvement of the dopaminergic system

(2012) D.G. Machado et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches

(2011) Juan José Ramírez-Espinosa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Management of type 2 diabetes: new and future developments in treatment

(2011) Abd A Tahrani et al.   LANCET

Synthesis, biology and clinical significance of pentacyclic triterpenes: a multi-target approach to prevention and treatment of metabolic and vascular diseases

(2011) Huaming Sheng et al.   NATURAL PRODUCT REPORTS

Small molecules from natural sources, targeting signaling pathways in diabetes

(2010) Qiong Liu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

11β-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches

(2010) Judith M. Rollinger et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antioxidant and antiatherogenic activities of pentacyclic triterpenic diols and acids

(2010) Yosra Allouche et al.   FOOD AND CHEMICAL TOXICOLOGY

Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice

(2009) Sun-Mi Jang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL