Article
Oncology
Yeong Jeong Jeon, Jong Ho Cho, Hong Kyu Lee, Hong Kwan Kim, Yong Soo Choi, Jae Ill Zo, Young Mog Shim
Summary: Bilateral RLNP following esophagectomy is rare but requires attention to prevent severe respiratory complications. The majority of patients are able to achieve oral ingestion after intensive rehabilitation, emphasizing the importance of feeding education and respiratory rehabilitation in managing these patients.
Review
Surgery
Do Hyun Kim, Jaeyoon Lee, Youngjun Seo, Sung Won Kim, Se Hwan Hwang
Summary: This study compares the results of transcutaneous laryngeal ultrasonography with laryngoscopy and finds that transcutaneous laryngeal ultrasonography can be used for evaluating vocal cord mobility with high diagnostic accuracy. It can be considered as an alternative method when laryngoscopy is not available or refused by patients.
AMERICAN JOURNAL OF SURGERY
(2022)
Article
Medicine, General & Internal
Iyad Hassan, Lina Hassan, Ibrahim Gamal, Mohamad Ibrahim, Abdel Rahman Omer
Summary: The aim of this study was to evaluate the diagnostic accuracy of the Abu Dhabi Neural Mapping protocol (ADNM) using the new device Nim-Vital (TM) in minimally invasive thyroidectomy. The results showed that following the ADNM protocol can minimize the risk of non-recurrent laryngeal nerve injury and prevent voice dysfunction.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Chang-Lun Huang, Chun-Min Chen, Wei-Heng Hung, Ya-Fu Cheng, Ruei-Ping Hong, Bing-Yen Wang, Ching-Yuan Cheng
Summary: Mediastinal lymph dissection in esophagectomy is crucial for patients with esophageal cancer. Intraoperative recurrent laryngeal nerve (RLN) monitoring can effectively prevent RLN injury and vocal cord palsy, as well as reduce the incidence of postoperative pneumonia.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Engineering, Biomedical
Hirut G. Kollech, Melissa R. Chao, Amanda C. Stark, Rebecca Z. German, Randal C. Paniello, Michael B. Christensen, Julie M. Barkmeier-Kraemer, Jonathan P. Vande Geest
Summary: Damage to the recurrent laryngeal nerve caused by external compression may contribute to vocal fold paralysis. The study found differences in composition and response to compression between the right and left nerves in pigs. This research sheds light on the etiology of idiopathic vocal fold paralysis.
ACTA BIOMATERIALIA
(2022)
Article
Endocrinology & Metabolism
Hsiao-Yu Huang, Ching-Feng Lien, Chih-Chun Wang, Chien-Chung Wang, Tzer-Zen Hwang, Yu-Chen Shih, Che-Wei Wu, Gianlorenzo Dionigi, Tzu-Yen Huang, Feng-Yu Chiang
Summary: The study demonstrates the necessity and value of routinely testing the proximal and distal ends of the exposed recurrent laryngeal nerve (RLN) during thyroid surgery. Testing the RLN helps detect nerve injuries, determine injury severity, and evaluate RLN function after surgery.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Emily K. Plowman, Neil Chheda, Amber Anderson, Justine Dallal York, Lauren DiBiase, Terrie Vasilopoulos, George Arnaoutakis, Thomas Beaver, Tomas Martin, Tamara Bateh, Eric I. Jeng
Summary: This study aimed to determine the incidence and risk factors of vocal fold mobility impairment (VFMI) in postoperative cardiovascular patients, highlighting independent risk factors for complete VFMI and the impact of VFMI on health-related outcomes. Findings showed that patients with complete VFMI had higher odds of complications and worse prognosis compared to those with normal vocal fold motion.
ANNALS OF THORACIC SURGERY
(2021)
Article
Clinical Neurology
Michael A. Belsky, R. Jun Lin, Clark A. Rosen, Michael C. Munin, Libby J. Smith
Summary: Temporary vocal fold injection (VFI) is a common treatment for acute and subacute vocal fold paralysis (VFP). Laryngeal electromyography (LEMG) is useful for diagnosing neurogenic causes of VFP. This study evaluated whether the presence of VFI material prevents interpretation of LEMG in patients with acute and subacute VFP.
Review
Surgery
Eoin F. Cleere, Matthew G. Davey, Orla Young, Aoife J. Lowery, Michael J. Kerin
Summary: This study conducted a systematic review and found that different methods of recurrent laryngeal nerve (RLN) preservation during thyroid surgery did not significantly affect the incidence of permanent RLN injury. However, intermittent intra-operative nerve monitoring and continuous intra-operative nerve monitoring were able to reduce the occurrence of transient RLN injury compared to no nerve monitoring.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Review
Medicine, General & Internal
Agastya Patel, Piotr Spychalski, Aleksander Aszkielowicz, Boguslaw Mikaszewski, Jarek Kobiela
Summary: TLUSG is an effective screening tool for vocal cord palsy, avoiding unnecessary laryngoscopic examination in around 80% of patients. Utilizing transverse and lateral approaches, as well as the Valsalva maneuver, can improve diagnostic accuracy. Male gender and older age are significant risk factors for vocal cord non-visualization.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Constantin Smaxwil, Miriam Aleker, Julia Altmeier, Ali Naddaf, Mirjam Busch, Joachim Wagner, Simone Harsch, Oswald Ploner, Andreas Zielke
Summary: The study found that intraoperative neuromonitoring can reduce the occurrence of postoperative vocal cord dysfunction following thyroid surgeries. It is recommended to use IONM in planned bilateral procedures to decrease the risk of bVCD.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cell & Tissue Engineering
Gary L. Clayman, Rashmi Roy, James Norman
Summary: This study found that intraoperative placement of a human amnion/chorion membrane (HACM) allograft on damaged recurrent laryngeal nerve (RLN) during thyroid surgery can reduce the occurrence and duration of RLN injury. These findings are significant in addressing a major complication of head and neck surgery.
CELL TRANSPLANTATION
(2022)
Article
Endocrinology & Metabolism
Jiaming Chen, Qi Zhong, Lizhen Hou, Hongzhi Ma, Qian Shi, Ling Feng, Shizhi He, Yansong Lin, Meng Lian, Xixi Shen, Ru Wang, Jugao Fang
Summary: This study retrospectively analyzed the clinicopathological characteristics of 171 papillary thyroid cancer patients and found that age of onset ≥55 years was an independent risk factor for postoperative recurrence. Preoperative voice analysis can predict recurrent laryngeal nerve function. PTC patients with RLN invasion can achieve good outcomes.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Critical Care Medicine
Camille E. Hamilton, Erik Su, Daniel Tawfik, Ernesto Fernandez, Ahmed Veten, Thomas Conlon, Sarah Ginsburg, Karley Mariano, Douglas Sidell, Bereketeab Haileselassie
Summary: The study found that laryngeal ultrasound has high sensitivity and specificity for detecting vocal cord motion in children, and is a low-risk imaging option compared to the current gold standard of laryngoscopy.
PEDIATRIC CRITICAL CARE MEDICINE
(2021)
Review
Otorhinolaryngology
Gillian R. Diercks, Jeff C. Rastatter, Ken Kazahaya, Dipti Kamani, Lourdes Quintanilla-Dieck, Maisie L. Shindo, Christopher Hartnick, Jennifer J. Shin, Michael C. Singer, Brendan C. Stack, Amy Y. Chen, Maie A. St John, Joseph Scharpf, Nishant Agrawal, Asitha D. L. Jayawardena, Ayaka J. Iwata, Okenwa Okose, Bo Wang, Dioan Mcilroy, Anthony Cheung, Che Wei Wu, Feng Yu Chiang, Gianlorenzo Dionigi, Marcin Barczynski, Katrin Brauckhoff, Kerstin Lorenz, Dana Hartl, Neil Tolley, Jennifer A. Brooks, Rick Schneider, Henning Dralle, Amr H. Abdelhamid Ahmed, Gregory W. Randolph
Summary: Children undergoing thyroid surgery are at higher risk of recurrent laryngeal nerve injury and intraoperative nerve monitoring (IONM) can help in nerve identification and surgical decision making. This literature review focuses on pediatric IONM and provides a guide for monitoring techniques and expert opinion statements. Various methods can be used for pediatric IONM, and technique selection depends on patient age and surgeon experience. Familiarity with monitoring techniques and interpretation is crucial for surgeons, and adult IONM guidelines may be applicable in pediatric cases as well. Delaying second-sided surgery can reduce bilateral RLN injury risk.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Surgery
Yoshiyuki Saito, Kenichi Matsuzu, Kiminori Sugino, Hiroshi Takami, Wataru Kitagawa, Mitsuji Nagahama, Koichi Ito
Article
Surgery
Yoshiyuki Saito, Yoshifumi Ikeda, Hiroshi Katoh, Atsushi Nakao, Hiroshi Takami
Summary: In this study, the risks and benefits of total endoscopic parathyroidectomy (TEP) for patients with primary hyperparathyroidism (PHPT) were evaluated. The operation time was significantly longer in the TEP group compared to the open minimally invasive parathyroidectomy (MIP) group, but common postoperative complications did not occur. Minimally invasive parathyroidectomy showed a high operative cure rate of 96.4%.
Editorial Material
Oncology
Yoshiyuki Saito, Hirofumi Kawakubo, Yuko Kitagawa
ANNALS OF SURGICAL ONCOLOGY
(2021)
Editorial Material
Surgery
Yoshifumi Ikeda, Yoshiyuki Saito, Tomohisa Kadomura, Roppei Yamada, Shun Shibuya, Hideki Itoh, Dai Ishiwa, Kazuma Tsuji, Zenko Nagashima, Satoru Segawa
Summary: The treatment of thyroid carcinoma invading into the thoracic cavity with severe airway stenosis is challenging due to the high risk of acute respiratory decompensation during anesthesia. ECMO, a life support technique, is used for severe, reversible respiratory or cardiac failure refractory to conventional management. While careful consideration of risks and benefits is necessary, the use of ECMO in anesthesia management can be a rational and effective strategy for maintaining oxygenation.
Article
Endocrinology & Metabolism
Whitney Liddy, Che-Wei Wu, Gianlorenzo Dionigi, Gianluca Donatini, Yasemin Giles Senyurek, Dipti Kamani, Ayaka Iwata, Bo Wang, Okenwa Okose, Anthony Cheung, Yoshiyuki Saito, Claudio Casella, Nurcihan Aygun, Mehmet Uludag, Katrin Brauckhoff, Bruno Carnaille, Fatih Tunca, Marcin Barczynski, Hoon Yub Kim, Emerson Favero, Nadia Innaro, Kyriakos Vamvakidis, Jonathan Serpell, Anatoly F. Romanchishen, Hiroshi Takami, Feng-Yu Chiang, Rick Schneider, Henning Dralle, Jennifer J. Shin, Amr H. Abdelhamid Ahmed, Gregory W. Randolph
Summary: During thyroid surgery, there is significant variability in the anatomic and intraoperative characteristics of the recurrent laryngeal nerve (RLN), which can impact the risk of neural injury. Multicenter international studies can help reshape understanding of surgical anatomy during thyroid surgery and identify potential factors contributing to nerve injury risk.
Article
Oncology
Juntaro Yamasaki, Yuki Hirata, Yuji Otsuki, Kentaro Suina, Yoshiyuki Saito, Kenta Masuda, Shogo Okazaki, Takatsugu Ishimoto, Hideyuki Saya, Osamu Nagano
Summary: Metastatic progression of tumors is driven by genetic alterations and tumor-stroma interaction. Using an organoid-based model of gastric cancer, researchers studied the mechanism underlying the metastasis of KRAS-mutated gastric cancer and found that an inhibitor of MAPK signaling could suppress metastasis.
Review
Otorhinolaryngology
Yoshiyuki Saito, Yoshifumi Ikeda, Hiroshi Takami, Amr H. Abdelhamid Ahmed, Atsushi Nakao, Hiroshi Katoh, Keiso Ho, Masato Tomita, Michio Sato, Neil S. Tolley, Gregory W. Randolph
Summary: After the description of the first remote-access parathyroidectomy (RAP) series in 2000, several other approaches have been developed. This study aimed to classify and evaluate RAP techniques through a literature review. A total of 71 studies met the inclusion/exclusion criteria and were analyzed. The findings suggest that the cure rates and safety of RAP are comparable to open parathyroidectomy, but each approach has its pros and cons. The selection of approach methods depends on the surgeon's experience and familiarity, as well as the patient's preference and disease status.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2022)
Article
Medicine, Research & Experimental
Jennifer A. Brooks, Amr H. Abdelhamid Ahmed, Zaid Al-Qurayshi, Dipti Kamani, Natalia Kyriazidis, Rebecca Jean Hammon, Hongzhi Ma, Niranjan Sritharan, Isaac Wasserman, Lily N. Trinh, Ayaka J. Iwata, Yoshiyuki Saito, Selen Soylu, Gregory W. Randolph
Summary: Invasion of the recurrent laryngeal nerve by thyroid carcinoma is an advanced disease with potential complications. Less than half of the patients had preoperative vocal cord paralysis. Complete tumor resection and RLN resection did not improve 5-year recurrence-free survival and overall survival, but postoperative radioactive iodine treatment was beneficial. Patients without preoperative vocal cord paralysis had higher IONM amplitude. Among the patients followed up, 35.9% had distant metastases and 36.4% had recurrence.
Article
Surgery
Keiso Ho, Yoshiyuki Saito, Yoshifumi Ikeda, Hiroshi Takami, Toshiki Tokuda, Ryohei Miyata, Masato Tomita, Michio Sato, Nobutoshi Ando
Summary: This article reports a case of remote-access thyroidectomy in a patient with a history of cervical radiation therapy. The procedure avoids neck scars and provides better cosmetic results, and can be safely performed even after irradiation.
Article
Surgery
Ludovico Sehnem, Salem Noureldine, Seyma Avci, Gizem Isiktas, Mohammed Elshamy, Yoshiyuki Saito, Amr H. A. Ahmed, Hien T. Tierney, Lily N. Trinh, Amanda Silver Karcioglu, Anthony Y. Cheung, Michael Otremba, Vikram Krishnamurthy, Katherine Heiden, Judy Jin, Joyce Shin, Allan Siperstein, Mark Zafereo, Ralph P. Tufano, Gregory W. Randolph, Electron Kebebew, Mira Milas, Quan-Yang Duh, Eren Berber
Summary: This study investigated the usefulness of incorporating near-infrared autofluorescence into thyroidectomy and parathyroidectomy procedures. The findings provide preliminary conclusions that can serve as a basis for further research on this technology.
Article
Otorhinolaryngology
Krupa R. Patel, Bo Wang, Amr Abdelhamid H. Ahmed, Okenwa C. Okose, Honghzhi Ma, Ian J. Behr, Anthony Y. Cheung, Yoshiyuki Saito, Dipti Kamani, Amanda Silver Karcioglu, Whitney Liddy, Hiroshi Takami, MaryBeth Cunnane, Gregory W. Randolph
Summary: This study aimed to investigate the surgical and biochemical outcomes of nerve-monitored reoperation or revision surgery for recurrent thyroid cancers. It was found that reoperation surgery may help achieve biochemical remission regardless of age or the number of prior surgeries.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Oncology
Yoshiyuki Saito, Natsuko Watanabe, Nami Suzuki, Naoko Saito, Hiroto Narimatsu, Hiroshi Takami, Kaori Kameyama, Kana Yoshioka, Chie Masaki, Junko Akaishi, Kiyomi Yamada Hames, Masako Matsumoto, Miho Fukushita, Ai Yoshihara, Ritsuko Okamura, Chisato Tomoda, Akifumi Suzuki, Kenichi Matsuzu, Wataru Kitagawa, Mitsuji Nagahama, Jaeduk Yoshimura Noh, Kiminori Sugino, Koichi Ito
Summary: This study aimed to establish an appropriate staging system and evaluate the role of surgery and radiation therapy in primary thyroid MALT lymphoma. The modified staging system allows discrimination between stage IE and IIE MALT lymphoma. Surgery provides good prognosis, avoids complications, shortens painful periods, and simplifies follow-up.
Article
Surgery
Yoshiyuki Saito, Yoshifumi Ikeda, Hiroshi Takami, Atsushi Nakao, Keiso Ho, Toshiki Tokuda, Ryohei Miyata, Masato Tomita, Michio Sato, Nobutoshi Ando
Summary: This study describes a novel technique for remote-access thyroidectomy for cervicomediastinal goiters. The results showed that most patients can have their thyroid tumors removed successfully using the axillary approach, with no complications occurring during the surgery.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Letter
Surgery
Y. Saito, H. Takami, A. H. Abdelhamid Ahmed, A. Nakao, K. Ho, T. Tokuda, R. Miyata, G. W. Randolph, N. Ando
Summary: The prevalence of primary hyperparathyroidism was higher in patients with symptomatic gallstones compared to healthy controls, suggesting potential clinical implications.
BRITISH JOURNAL OF SURGERY
(2021)
Article
Orthopedics
Atsushi Nakao, Yoshiyuki Saito, Yoshifumi Ikeda, Hiroshi Takami, Go Hoshino, Ryohei Miyata, Masato Tomita, Michio Sato, Naoyo Ishikura, Toshiyuki Mitsuya, Nobutoshi Ando
Summary: TET is a newly established surgical approach that can avoid scarring in the neck and is suitable for specific cases. This case demonstrates that TET provides superior cosmetic outcomes and can be considered for reoperation.
ASIAN JOURNAL OF ENDOSCOPIC SURGERY
(2021)
