Dietary carbohydrates impair the protective effect of protein restriction against diabetes in NZO mice used as a model of type 2 diabetes

Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints

(2017) Cristal M. Hill et al.   Scientific Reports

Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework

(2016) Samantha M. Solon-Biet et al.   Cell Metabolism

Fibroblast growth factor 21 improves hepatic insulin sensitivity by inhibiting mammalian target of rapamycin complex 1 in mice

(2016) Qi Gong et al.   HEPATOLOGY

A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution

(2016) Adriano Maida et al.   JOURNAL OF CLINICAL INVESTIGATION

Fibroblast growth factor 21 night watch: advances and uncertainties in the field

(2016) A. Kharitonenkov et al.   JOURNAL OF INTERNAL MEDICINE

Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health

(2016) Luigi Fontana et al.   Cell Reports

Metabolic Responses to Dietary Protein Restriction Require an Increase in FGF21 that Is Delayed by the Absence of GCN2

(2016) Thomas Laeger et al.   Cell Reports

Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas

(2016) Garima Singhal et al.   PLoS One

Caloric restriction and intermittent fasting alter hepatic lipid droplet proteome and diacylglycerol species and prevent diabetes in NZO mice

(2015) Christian Baumeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base

(2015) Richard D. Feinman et al.   NUTRITION

Protein-dependent regulation of feeding and metabolism

(2015) Christopher D. Morrison et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice

(2015) Samantha M. Solon-Biet et al.   Cell Reports

Identification of Four Mouse Diabetes Candidate Genes Altering β-Cell Proliferation

(2015) Oliver Kluth et al.   PLoS Genetics

Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?

(2015) Brian N. Finck et al.   Biomed Research International

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

(2014) Samantha M. Solon-Biet et al.   Cell Metabolism

Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

(2014) Morgan E. Levine et al.   Cell Metabolism

Fasting: Molecular Mechanisms and Clinical Applications

(2014) Valter D. Longo et al.   Cell Metabolism

Head Over Hepatocytes for FGF21

(2014) M. J. Potthoff et al.   DIABETES

FGF21 is an endocrine signal of protein restriction

(2014) Thomas Laeger et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of high-protein diets on body weight, glycaemic control, blood lipids and blood pressure in type 2 diabetes: meta-analysis of randomised controlled trials

(2013) Jia-Yi Dong et al.   BRITISH JOURNAL OF NUTRITION

Health effects of protein intake in healthy adults: a systematic literature review

(2013) Agnes N. Pedersen et al.   Food & Nutrition Research

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes

(2012) Joo-Won Park et al.   HEPATOLOGY

Response of C57Bl/6 mice to a carbohydrate-free diet

(2012) Saihan Borghjid et al.   Nutrition & Metabolism

Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats

(2010) D. A. Sarruf et al.   DIABETES

Pathogenesis of Fasting and Postprandial Hyperglycemia in Type 2 Diabetes: Implications for Therapy

(2010) R. A. Rizza   DIABETES

Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure

(2010) O. Kluth et al.   DIABETOLOGIA

Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights fromin VivoManipulation of Sphingolipid Metabolism

(2008) William L. Holland et al.   ENDOCRINE REVIEWS