Dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, slows the progression of renal complications through the suppression of renal inflammation, endoplasmic reticulum stress and apoptosis in prediabetic rats
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, slows the progression of renal complications through the suppression of renal inflammation, endoplasmic reticulum stress and apoptosis in prediabetic rats
Authors
Keywords
-
Journal
DIABETES OBESITY & METABOLISM
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-06-20
DOI
10.1111/dom.13441
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dapagliflozin Aggravates Renal Injury via Promoting Gluconeogenesis in db/db Mice
- (2018) Yingli Jia et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Diacerein alleviates kidney injury through attenuating inflammation and oxidative stress in obese insulin-resistant rats
- (2018) Nuttawud Chueakula et al. FREE RADICAL BIOLOGY AND MEDICINE
- Prebiotic prevents impaired kidney and renal Oat3 functions in obese rats
- (2018) Keerati Wanchai et al. JOURNAL OF ENDOCRINOLOGY
- SGLT2 Protein Expression Is Increased in Human Diabetic Nephropathy
- (2017) Xiaoxin X. Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inflammatory stress promotes the development of obesity-related chronic kidney disease via CD36 in mice
- (2017) Ping Yang et al. JOURNAL OF LIPID RESEARCH
- The effect of SGLT2 inhibitors on cardiovascular events and renal function
- (2017) Konstantinos P. Imprialos et al. Expert Review of Clinical Pharmacology
- Chronic kidney disease
- (2017) Paola Romagnani et al. Nature Reviews Disease Primers
- Sodium glucose cotransporter 2 inhibition in the diabetic kidney
- (2016) Aleksandra Novikov et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- SGLT2 Inhibition and cardiovascular events: why did EMPA-REG Outcomes surprise and what were the likely mechanisms?
- (2016) Naveed Sattar et al. DIABETOLOGIA
- Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
- (2016) Maria Edeling et al. Nature Reviews Nephrology
- Effect of Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin, on Renal Renin-Angiotensin System in an Animal Model of Type 2 Diabetes
- (2016) Seok Joon Shin et al. PLoS One
- Amelioration of Renal Inflammation, Endoplasmic Reticulum Stress and Apoptosis Underlies the Protective Effect of Low Dosage of Atorvastatin in Gentamicin-Induced Nephrotoxicity
- (2016) Krit Jaikumkao et al. PLoS One
- Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice
- (2016) Linda A. Gallo et al. Scientific Reports
- Central Inhibition of IKKβ/NF-κB Signaling Attenuates High-Fat Diet–Induced Obesity and Glucose Intolerance
- (2015) Jonas Benzler et al. DIABETES
- Empagliflozin, an Inhibitor of Sodium-Glucose Cotransporter 2 Exerts Anti-Inflammatory and Antifibrotic Effects on Experimental Diabetic Nephropathy Partly by Suppressing AGEs-Receptor Axis
- (2015) A. Ojima et al. HORMONE AND METABOLIC RESEARCH
- Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
- (2015) Caroline Bonner et al. NATURE MEDICINE
- Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
- (2015) Bernard Zinman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Insulin stimulates SGLT2-mediated tubular glucose absorption via oxidative stress generation
- (2015) Nobutaka Nakamura et al. Diabetology & Metabolic Syndrome
- Acetaminophen Attenuates Obesity-Related Renal Injury Through ER-Mediated Stress Mechanisms
- (2014) Cuifen Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Safety Profile of Dapagliflozin for Type 2 Diabetes: Pooled Analysis of Clinical Studies for Overall Safety and Rare Events
- (2014) Agata Ptaszynska et al. DRUG SAFETY
- Stress in the kidney is the road to pERdition: is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy?
- (2014) Aowen Zhuang et al. JOURNAL OF ENDOCRINOLOGY
- Long-Term Treatment with the Sodium Glucose Cotransporter 2 Inhibitor, Dapagliflozin, Ameliorates Glucose Homeostasis and Diabetic Nephropathy in db/db Mice
- (2014) Naoto Terami et al. PLoS One
- Dapagliflozin Is Effective as Add-on Therapy to Sitagliptin With or Without Metformin: A 24-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study
- (2013) Serge A. Jabbour et al. DIABETES CARE
- Dapagliflozin a glucose-regulating drug with diuretic properties in subjects with type 2 diabetes
- (2013) H. J. Lambers Heerspink et al. DIABETES OBESITY & METABOLISM
- Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells
- (2013) Dian-liang Fang et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells—Renoprotection in Diabetic Nephropathy?
- (2013) Usha Panchapakesan et al. PLoS One
- Metformin nephrotoxicity insights: Will they change clinical management? (二甲双胍肾毒性的见解:它们会导致临床治疗出现变化吗?)
- (2013) Celeste C. Thomas et al. Journal of Diabetes
- Sodium glucose cotransporter 2 and the diabetic kidney
- (2012) Muralikrishna Gangadharan Komala et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Prediabetic Nephropathy as an Early Consequence of the High-Calorie/High-Fat Diet: Relation to Oxidative Stress
- (2012) Hanna Shevalye et al. ENDOCRINOLOGY
- Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease
- (2012) Alexandra K. Leamy et al. PROGRESS IN LIPID RESEARCH
- Renal Function in Diabetic Disease Models: The Tubular System in the Pathophysiology of the Diabetic Kidney
- (2011) Volker Vallon et al. Annual Review of Physiology
- AMPK Mediates the Initiation of Kidney Disease Induced by a High-Fat Diet
- (2011) A.-E. Decleves et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
- (2011) Suneng Fu et al. NATURE
- Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
- (2011) Ira Tabas et al. NATURE CELL BIOLOGY
- Focal Segmental Glomerulosclerosis
- (2011) Vivette D. D'Agati et al. NEW ENGLAND JOURNAL OF MEDICINE
- Pathogenic perspectives for the role of inflammation in diabetic nephropathy
- (2009) Antonio Rivero et al. CLINICAL SCIENCE
- Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria
- (2009) Alexandra Jauregui et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Expression and Activity of SGLT2 in Diabetes Induced by Streptozotocin: Relationship with the Lipid Environment
- (2009) María F. Albertoni Borghese et al. NEPHRON PHYSIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started