Folate action in nervous system development and disease

Implications of DNA Methylation in Parkinson’s Disease

(2017) Ernesto Miranda-Morales et al.   Frontiers in Molecular Neuroscience

The metabolic basis for developmental disorders due to defective folate transport

(2016) Ankuri Desai et al.   BIOCHIMIE

Identification of a Chemoattractant G-Protein-Coupled Receptor for Folic Acid that Controls Both Chemotaxis and Phagocytosis

(2016) Miao Pan et al.   DEVELOPMENTAL CELL

Cell-cycle-dependent TGFβ–BMP antagonism regulates neural tube closure by modulating tight junctions

(2016) Smita Amarnath et al.   JOURNAL OF CELL SCIENCE

One-carbon metabolism and epigenetics: understanding the specificity

(2015) Samantha J. Mentch et al.   Annals of the New York Academy of Sciences

Planar polarization of Vangl2 in the vertebrate neural plate is controlled by Wnt and Myosin II signaling

(2015) O. Ossipova et al.   Biology Open

GEF-H1 functions in apical constriction and cell intercalations and is essential for vertebrate neural tube closure

(2014) K. Itoh et al.   JOURNAL OF CELL SCIENCE

LRP2 mediates folate uptake in the developing neural tube

(2014) Esther Kur et al.   JOURNAL OF CELL SCIENCE

Juno is the egg Izumo receptor and is essential for mammalian fertilization

(2014) Enrica Bianchi et al.   NATURE

Adherens junction treadmilling during collective migration

(2014) Florent Peglion et al.   NATURE CELL BIOLOGY

B vitamin polymorphisms and behavior: Evidence of associations with neurodevelopment, depression, schizophrenia, bipolar disorder and cognitive decline

(2014) E. Siobhan Mitchell et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Fetal surgery for myelomeningocele is effective: a critical look at the whys

(2014) Martin Meuli et al.   PEDIATRIC SURGERY INTERNATIONAL

Role of Rab11 in planar cell polarity and apical constriction during vertebrate neural tube closure

(2014) Olga Ossipova et al.   Nature Communications

The Continuing Challenge of Understanding, Preventing, and Treating Neural Tube Defects

(2013) J. B. Wallingford et al.   SCIENCE

Bone morphogenetic proteins regulate hinge point formation during neural tube closure by dynamic modulation of apicobasal polarity

(2012) Dae Seok Eom et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Molecular characterization of folate receptor 1 mutations delineates cerebral folate transport deficiency

(2012) M. Grapp et al.   BRAIN

SKI-1 and Furin Generate Multiple RGMa Fragments that Regulate Axonal Growth

(2012) Nardos G. Tassew et al.   DEVELOPMENTAL CELL

Homocysteinylation of neuronal proteins contributes to folate deficiency-associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal cells

(2012) Nassila Akchiche et al.   FASEB JOURNAL

Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice

(2012) J. Momb et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebral Folate Deficiency Syndromes in Childhood

(2011) Belén Pérez-Dueñas et al.   ARCHIVES OF NEUROLOGY

Bone morphogenetic proteins regulate neural tube closure by interacting with the apicobasal polarity pathway

(2011) D. S. Eom et al.   DEVELOPMENT

Endocytic and Recycling Endosomes Modulate Cell Shape Changes and Tissue Behaviour during Morphogenesis in Drosophila

(2011) Ana Margarida Mateus et al.   PLoS One

Association of folate receptor (folr1, folr2, folr3) and reduced folate carrier (slc19a1) genes with meningomyelocele

(2010) Michelle R. O'Byrne et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Endocytosis Is Required for Efficient Apical Constriction during Xenopus Gastrulation

(2010) Jen-Yi Lee et al.   CURRENT BIOLOGY

Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation

(2010) Bermans J. Iskandar et al.   JOURNAL OF CLINICAL INVESTIGATION

Progressive ataxia and myoclonic epilepsy in a patient with a homozygous mutation in the FOLR1 gene

(2010) Belén Pérez-Dueñas et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Folate Receptor Alpha Defect Causes Cerebral Folate Transport Deficiency: A Treatable Neurodegenerative Disorder Associated with Disturbed Myelin Metabolism

(2009) Robert Steinfeld et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Regulation of Folate Receptor Internalization by Protein Kinase C α

(2009) Hala Elnakat et al.   BIOCHEMISTRY

N- and E-cadherins in Xenopus are specifically required in the neural and non-neural ectoderm, respectively, for F-actin assembly and morphogenetic movements

(2009) S. Nandadasa et al.   DEVELOPMENT

Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues

(2009) Rongbao Zhao et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Steric and not structure-specific factors dictate the endocytic mechanism of glycosylphosphatidylinositol-anchored proteins

(2009) Pinkesh Bhagatji et al.   JOURNAL OF CELL BIOLOGY

Enhancement of Notch receptor maturation and signaling sensitivity by Cripto-1

(2009) Kazuhide Watanabe et al.   JOURNAL OF CELL BIOLOGY

One-Carbon Metabolism–Genome Interactions in Folate-Associated Pathologies

(2009) Patrick J. Stover   JOURNAL OF NUTRITION

Folic Acid and Risk of Prostate Cancer: Results From a Randomized Clinical Trial

(2009) J. C. Figueiredo et al.   JNCI-Journal of the National Cancer Institute

Circulating Concentrations of Folate and Vitamin B12 in Relation to Prostate Cancer Risk: Results from the European Prospective Investigation into Cancer and Nutrition Study

(2008) M. Johansson et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Shroom3-mediated recruitment of Rho kinases to the apical cell junctions regulates epithelial and neuroepithelial planar remodeling

(2008) T. Nishimura et al.   DEVELOPMENT

A Role for the Proton-coupled Folate Transporter (PCFT-SLC46A1) in Folate Receptor-mediated Endocytosis

(2008) Rongbao Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase

(2008) G. Kronenberg et al.   JOURNAL OF NEUROSCIENCE

Pulsed contractions of an actin–myosin network drive apical constriction

(2008) Adam C. Martin et al.   NATURE

Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain

(2008) Yasuhiko Kawasaki et al.   NATURE MEDICINE

Cholesterol Level Regulates Endosome Motility via Rab Proteins

(2007) Hongtao Chen et al.   BIOPHYSICAL JOURNAL